STRINGSTRING
HEYL HEYL HEY2 HEY2 BMP2 BMP2 OLFM1 OLFM1 GATA4 GATA4 SMAD4 SMAD4 MDM4 MDM4 CCN1 CCN1 ACVR1 ACVR1 EFNA1 EFNA1 BMPR2 BMPR2 SLIT3 SLIT3 TBX5 TBX5 BMPR1A BMPR1A ZFPM1 ZFPM1 NOTCH1 NOTCH1 HEY1 HEY1 SMAD6 SMAD6 TGFBR2 TGFBR2 TGFB2 TGFB2 SOX4 SOX4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
OLFM1Olfactomedin 1. (485 aa)
GATA4GATA binding protein 4. (445 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
MDM4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (491 aa)
CCN1Cellular communication network factor 1. (381 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (510 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1037 aa)
SLIT3Slit guidance ligand 3. (1523 aa)
TBX5T-box transcription factor 5. (518 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (484 aa)
ZFPM1Zinc finger protein, FOG family member 1. (728 aa)
NOTCH1Notch receptor 1. (2420 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (308 aa)
SMAD6Mothers against decapentaplegic homolog. (500 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
SOX4Transcription factor SOX. (479 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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