Your Input: | |||||
DDB2 | Damage specific DNA binding protein 2. (426 aa) | ||||
TP53BP1 | Tumor protein p53 binding protein 1. (1974 aa) | ||||
MSH6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1229 aa) | ||||
DDB1 | Damage specific DNA binding protein 1. (1142 aa) | ||||
SDE2 | SDE2 telomere maintenance homolog. (286 aa) | ||||
DCLRE1A | DRMBL domain-containing protein. (506 aa) | ||||
PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) | ||||
POLH | DNA polymerase eta. (709 aa) | ||||
LOC105817821 | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (689 aa) | ||||
ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit. (681 aa) | ||||
RBBP8 | RB binding protein 8, endonuclease. (865 aa) | ||||
ENSPCOP00000012342 | RING-type domain-containing protein. (80 aa) | ||||
LOC105811387 | XRCC1_N domain-containing protein. (142 aa) | ||||
MPG | N-methylpurine DNA glycosylase. (284 aa) | ||||
POLD1 | DNA polymerase. (1125 aa) | ||||
NTHL1 | Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (312 aa) | ||||
XPA | XPA, DNA damage recognition and repair factor. (251 aa) | ||||
PNKP | Polynucleotide kinase 3'-phosphatase. (521 aa) | ||||
APEX1 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (318 aa) | ||||
EP300 | E1A binding protein p300. (2424 aa) | ||||
TDG | Thymine DNA glycosylase. (256 aa) | ||||
ENSPCOP00000020030 | KH type-2 domain-containing protein. (93 aa) | ||||
MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (868 aa) | ||||
XRCC5 | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (677 aa) | ||||
RECQL4 | RecQ like helicase 4. (842 aa) | ||||
REV1 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1197 aa) | ||||
ERCC4 | ERCC excision repair 4, endonuclease catalytic subunit. (879 aa) | ||||
POT1 | Protection of telomeres 1. (600 aa) | ||||
NEIL3 | Nei like DNA glycosylase 3. (423 aa) | ||||
ENSPCOP00000002676 | Uncharacterized protein; Belongs to the transient receptor (TC 1.A.4) family. (879 aa) | ||||
POLI | DNA polymerase iota. (735 aa) | ||||
CREBBP | CREB binding protein. (2449 aa) | ||||
FANCG | FA complementation group G. (621 aa) | ||||
DCLRE1B | DNA cross-link repair 1B. (529 aa) | ||||
RPA3 | Replication protein A3. (107 aa) | ||||
NEIL2 | Nei like DNA glycosylase 2. (217 aa) | ||||
RAD23A | RAD23 homolog A, nucleotide excision repair protein. (365 aa) | ||||
ENSPCOP00000023392 | Uncharacterized protein. (157 aa) | ||||
XPC | XPC complex subunit, DNA damage recognition and repair factor. (867 aa) | ||||
ENSPCOP00000024882 | Ribosomal_S3_C domain-containing protein. (231 aa) | ||||
POLQ | DNA polymerase theta. (2280 aa) | ||||
XRCC1 | X-ray repair cross complementing 1. (598 aa) | ||||
POLB | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (333 aa) | ||||
UNG | Uracil DNA glycosylase. (261 aa) | ||||
ENSPCOP00000027398 | KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (281 aa) | ||||
OGG1 | 8-oxoguanine DNA glycosylase. (380 aa) | ||||
XRCC6 | X-ray repair cross complementing 6. (496 aa) | ||||
NEIL1 | Nei like DNA glycosylase 1. (390 aa) | ||||
POLK | DNA polymerase kappa. (832 aa) | ||||
ENSPCOP00000030730 | Uncharacterized protein. (103 aa) | ||||
TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa) | ||||
SMC6 | Structural maintenance of chromosomes 6. (933 aa) | ||||
AUNIP | Aurora kinase A and ninein interacting protein. (321 aa) | ||||
SIRT6 | Sirtuin 6. (305 aa) | ||||
RPS3 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa) | ||||
ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit. (298 aa) | ||||
CRY2 | Cryptochrome circadian regulator 2. (593 aa) | ||||
RAD23B | RAD23 homolog B, nucleotide excision repair protein. (409 aa) | ||||
MUTYH | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (549 aa) | ||||
RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa) | ||||
BLM | BLM RecQ like helicase. (1352 aa) |