STRINGSTRING
DHDH DHDH SLC25A10 SLC25A10 MAPK14 MAPK14 LOC105825252 LOC105825252 KCNQ1 KCNQ1 GCLC GCLC FPGT FPGT PDHA1 PDHA1 ENSPCOP00000016963 ENSPCOP00000016963 PMM1 PMM1 KAT2A KAT2A PFKFB1 PFKFB1 TFAP2B TFAP2B G6PC3 G6PC3 PIK3CA PIK3CA TNF TNF WDTC1 WDTC1 GALK1 GALK1 PGM1 PGM1 AKR1A1 AKR1A1 MAN2B1 MAN2B1 RGN RGN PC PC PDHB PDHB ENSPCOP00000013232 ENSPCOP00000013232 ADIPOQ ADIPOQ MAN2C1 MAN2C1 GALM GALM HK2 HK2 LOC105822391 LOC105822391 PPARA PPARA B4GALT1 B4GALT1 INPPL1 INPPL1 SLC39A14 SLC39A14 ENO3 ENO3 SLC23A2 SLC23A2 LEPR LEPR DCXR DCXR GCG GCG GALK2 GALK2 POFUT2 POFUT2 LOC105819868 LOC105819868 PGAM2 PGAM2 PDK4 PDK4 CHST15 CHST15 GCK GCK FOXK1 FOXK1 FOXK2 FOXK2 GPD1 GPD1 PGD PGD TPI1 TPI1 LOC105822347 LOC105822347 PCK1 PCK1 RBKS RBKS PER2 PER2 KBTBD2 KBTBD2 MAN2A1 MAN2A1 PPARD PPARD BAD BAD C1QTNF12 C1QTNF12 IGF2 IGF2 PFKFB3 PFKFB3 SLC25A1 SLC25A1 GAL3ST3 GAL3ST3 RBP4 RBP4 H6PD H6PD G6PC G6PC AKT1 AKT1 PGM2 PGM2 WDR5 WDR5 GHRL GHRL ALDOB ALDOB PCK2 PCK2 PGM2L1 PGM2L1 POFUT1 POFUT1 FBN1 FBN1 FUCA2 FUCA2 XYLB XYLB ENSPCOP00000026551 ENSPCOP00000026551 FUT10 FUT10 HK3 HK3 ENO1 ENO1 SLC37A4 SLC37A4 OMA1 OMA1 PDK2 PDK2 SERPINA12 SERPINA12 HKDC1 HKDC1 PRKAA1 PRKAA1 ENSPCOP00000023327 ENSPCOP00000023327 SLC35A2 SLC35A2 NUDT5 NUDT5 OTOG OTOG ADPGK ADPGK TKTL1 TKTL1 BRAT1 BRAT1 PPARGC1A PPARGC1A ENSPCOP00000021134 ENSPCOP00000021134 FUT7 FUT7 AKR1B1 AKR1B1 PDK3 PDK3 CRTC2 CRTC2 G6PC2 G6PC2 SDS SDS CPT1A CPT1A PFKFB2 PFKFB2 TKFC TKFC LOC105820200 LOC105820200 B3GLCT B3GLCT TSTD1 TSTD1 FBP2 FBP2 SLC2A1 SLC2A1 PDX1 PDX1 GAPDHS GAPDHS UXS1 UXS1 KCNJ11 KCNJ11 TIGAR TIGAR PDK1 PDK1 SLC23A1 SLC23A1 APOD APOD MAN2B2 MAN2B2 TKTL2 TKTL2 RPIA RPIA GALE GALE CRY1 CRY1 LEP LEP DLAT DLAT GSTO2 GSTO2 ATF3 ATF3 HK1 HK1 CDV3 CDV3 FABP5 FABP5 MAN2A2 MAN2A2 GAPDH GAPDH FUCA1 FUCA1 FBP1 FBP1 PFKFB4 PFKFB4 LOC105824234 LOC105824234 G6PD G6PD FGGY FGGY TP53 TP53 ENO2 ENO2 KHK KHK GPI GPI AKT2 AKT2 HECTD4 HECTD4 LOC105826747 LOC105826747 ATF4 ATF4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DHDHDihydrodiol dehydrogenase. (334 aa)
SLC25A10Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (287 aa)
MAPK14Mitogen-activated protein kinase 14. (340 aa)
LOC105825252FAD-binding PCMH-type domain-containing protein. (446 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (545 aa)
GCLCGlutamate-cysteine ligase catalytic subunit. (637 aa)
FPGTFucose-1-phosphate guanylyltransferase. (599 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (387 aa)
ENSPCOP00000016963Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (200 aa)
PMM1Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (262 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (835 aa)
PFKFB16-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. (471 aa)
TFAP2BTranscription factor AP-2 beta. (460 aa)
G6PC3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa)
PIK3CAPhosphatidylinositol 3-kinase catalytic subunit type 3. (933 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (235 aa)
WDTC1WD and tetratricopeptide repeats 1. (677 aa)
GALK1Galactokinase 1. (392 aa)
PGM1Phosphoglucomutase 1; Belongs to the phosphohexose mutase family. (580 aa)
AKR1A1Aldo_ket_red domain-containing protein. (326 aa)
MAN2B1Alpha-mannosidase. (1010 aa)
RGNRegucalcin. (299 aa)
PCPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1178 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
ENSPCOP00000013232Protein-serine/threonine kinase. (359 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
MAN2C1Mannosidase alpha class 2C member 1. (1059 aa)
GALMGalactose mutarotase. (290 aa)
HK2Hexokinase 2. (841 aa)
LOC105822391FBPase domain-containing protein; Belongs to the FBPase class 1 family. (278 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
B4GALT1Beta-1,4-galactosyltransferase 1. (398 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1264 aa)
SLC39A14Solute carrier family 39 member 14. (490 aa)
ENO3Enolase 3. (434 aa)
SLC23A2Solute carrier family 23 member 2. (632 aa)
LEPRLeptin receptor. (1055 aa)
DCXRDicarbonyl and L-xylulose reductase. (226 aa)
GCGGlucagon. (180 aa)
GALK2Galactokinase 2. (458 aa)
POFUT2Protein O-fucosyltransferase 2. (364 aa)
LOC105819868Protein kinase domain-containing protein. (302 aa)
PGAM2Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
PDK4Protein-serine/threonine kinase. (412 aa)
CHST15Carbohydrate sulfotransferase 15. (560 aa)
GCKPhosphotransferase. (466 aa)
FOXK1Forkhead box K1. (731 aa)
FOXK2Forkhead box K2. (631 aa)
GPD1Glycerol-3-phosphate dehydrogenase [NAD(+)]. (349 aa)
PGDPhosphogluconate dehydrogenase. (438 aa)
TPI1Triosephosphate isomerase. (286 aa)
LOC105822347Triosephosphate isomerase. (240 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
RBKSRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (322 aa)
PER2Period circadian regulator 2. (1265 aa)
KBTBD2Kelch repeat and BTB domain containing 2. (623 aa)
MAN2A1Alpha-mannosidase. (1142 aa)
PPARDPeroxisome proliferator activated receptor delta. (440 aa)
BADBCL2 associated agonist of cell death. (168 aa)
C1QTNF12C1q and TNF related 12. (294 aa)
IGF2Insulin like growth factor 2. (236 aa)
PFKFB36-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3. (544 aa)
SLC25A1Solute carrier family 25 member 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (223 aa)
GAL3ST3Galactose-3-O-sulfotransferase 3. (431 aa)
RBP4Retinol-binding protein; Retinol-binding protein that mediates retinol transport in blood plasma. (201 aa)
H6PDHexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (781 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PGM2Uncharacterized protein. (609 aa)
WDR5WD repeat domain 5. (334 aa)
GHRLGhrelin and obestatin prepropeptide. (116 aa)
ALDOBFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa)
PGM2L1Phosphoglucomutase 2 like 1. (622 aa)
POFUT1Protein O-fucosyltransferase 1. (391 aa)
FBN1Fibrillin 1. (2871 aa)
FUCA2Alpha-L-fucosidase 2. (391 aa)
XYLBXylulokinase. (536 aa)
ENSPCOP00000026551Bromo domain-containing protein. (84 aa)
FUT10Alpha-(1,3)-fucosyltransferase; Probable fucosyltransferase; Belongs to the glycosyltransferase 10 family. (479 aa)
HK3Hexokinase 3. (924 aa)
ENO1Enolase 1. (434 aa)
SLC37A4Solute carrier family 37 member 4. (451 aa)
OMA1OMA1 zinc metallopeptidase. (524 aa)
PDK2Protein-serine/threonine kinase. (407 aa)
SERPINA12Serpin family A member 12; Belongs to the serpin family. (413 aa)
HKDC1Hexokinase domain containing 1. (869 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
ENSPCOP00000023327Uncharacterized protein; Belongs to the phosphohexose mutase family. (526 aa)
SLC35A2Solute carrier family 35 member A2. (427 aa)
NUDT5Nudix hydrolase 5; Belongs to the Nudix hydrolase family. (232 aa)
OTOGOtogelin. (2905 aa)
ADPGKADP dependent glucokinase. (497 aa)
TKTL1Transketolase like 1. (540 aa)
BRAT1BRCA1 associated ATM activator 1. (822 aa)
PPARGC1APPARG coactivator 1 alpha. (809 aa)
ENSPCOP00000021134E1_dh domain-containing protein. (188 aa)
FUT7Fucosyltransferase 7. (342 aa)
AKR1B1Aldo-keto reductase family 1 member B. (316 aa)
PDK3Protein-serine/threonine kinase. (352 aa)
CRTC2CREB regulated transcription coactivator 2. (686 aa)
G6PC2Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa)
SDSSerine dehydratase. (328 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (697 aa)
PFKFB26-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2. (507 aa)
TKFCTriokinase and FMN cyclase. (579 aa)
LOC105820200Aldo_ket_red domain-containing protein. (325 aa)
B3GLCTBeta 3-glucosyltransferase. (479 aa)
TSTD1Thiosulfate sulfurtransferase like domain containing 1. (115 aa)
FBP2Fructose-bisphosphatase 2; Belongs to the FBPase class 1 family. (339 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (495 aa)
PDX1Pancreatic and duodenal homeobox 1. (282 aa)
GAPDHSGlyceraldehyde-3-phosphate dehydrogenase. (404 aa)
UXS1UDP-glucuronate decarboxylase 1. (425 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (390 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (270 aa)
PDK1Protein-serine/threonine kinase. (438 aa)
SLC23A1Solute carrier family 23 member 1. (598 aa)
APODApolipoprotein D. (189 aa)
MAN2B2Alpha-mannosidase. (1012 aa)
TKTL2Transketolase like 2. (607 aa)
RPIARibose 5-phosphate isomerase A. (311 aa)
GALEUDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (348 aa)
CRY1Cryptochrome circadian regulator 1. (550 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
DLATDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (606 aa)
GSTO2Glutathione S-transferase omega 2; Belongs to the GST superfamily. (243 aa)
ATF3Activating transcription factor 3. (181 aa)
HK1Hexokinase 1. (881 aa)
CDV3CDV3 homolog. (258 aa)
FABP5Fatty acid binding protein 5; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
MAN2A2Alpha-mannosidase. (1150 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (335 aa)
FUCA1Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. (418 aa)
FBP1FBPase domain-containing protein; Belongs to the FBPase class 1 family. (338 aa)
PFKFB46-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4. (469 aa)
LOC105824234Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (303 aa)
G6PDGlucose-6-phosphate dehydrogenase. (558 aa)
FGGYFGGY carbohydrate kinase domain containing. (551 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa)
ENO2Enolase 2. (434 aa)
KHKKetohexokinase. (298 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (572 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
HECTD4HECT domain E3 ubiquitin protein ligase 4. (4216 aa)
LOC105826747Gp_dh_N domain-containing protein. (313 aa)
ATF4Activating transcription factor 4. (351 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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