54 items (Propithecus coquereli) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PCK1	Phosphoenolpyruvate carboxykinase 1. (622 aa)
	GPIHBP1	Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1. (177 aa)
	LIPF	Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (401 aa)
	LPIN2	Lipin 2. (830 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
	G6PC	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
	GK5	Glycerol kinase 5; Belongs to the FGGY kinase family. (500 aa)
	SIRT1	Sirtuin 1. (743 aa)
	PCK2	Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa)
	MOGAT3	Monoacylglycerol O-acyltransferase 3. (341 aa)
	SLC37A4	Solute carrier family 37 member 4. (451 aa)
	SEL1L	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase. (794 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
	GPAT2	Glycerol-3-phosphate acyltransferase 2, mitochondrial. (794 aa)
	LIPE	Lipase E, hormone sensitive type. (1052 aa)
	MOGAT1	Monoacylglycerol O-acyltransferase 1. (335 aa)
	APOA5	Apolipoprotein A5. (371 aa)
	LPL	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (474 aa)
	GPAT4	Glycerol-3-phosphate acyltransferase 4. (456 aa)
	CPS1	Carbamoyl-phosphate synthase 1. (1310 aa)
	TNXB	Uncharacterized protein. (3508 aa)
	GPAT3	Glycerol-3-phosphate acyltransferase 3. (354 aa)
	PNPLA5	Patatin like phospholipase domain containing 5. (432 aa)
	LPGAT1	Lysophosphatidylglycerol acyltransferase 1. (327 aa)
	ENSPCOP00000007071	Hydrolase_4 domain-containing protein. (153 aa)
	PNPLA2	Patatin like phospholipase domain containing 2. (480 aa)
	LMF1	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family. (347 aa)
	APOBEC1	Apolipoprotein B mRNA editing enzyme catalytic subunit 1. (226 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	PNPLA3	Patatin like phospholipase domain containing 3. (475 aa)
	PLAAT3	Phospholipase A and acyltransferase 3. (162 aa)
	PNPLA1	Patatin like phospholipase domain containing 1. (453 aa)
	CPT1A	Carnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (697 aa)
	APOB	Apolipoprotein B. (4538 aa)
	SLC27A5	Solute carrier family 27 member 5. (690 aa)
	NKX2-3	NK2 homeobox 3. (361 aa)
	ACSL1	Acyl-CoA synthetase long chain family member 1. (664 aa)
	DGAT2	Diacylglycerol O-acyltransferase 2. (388 aa)
	LPIN1	Lipin 1. (972 aa)
	SLC22A4	Solute carrier family 22 member 4. (551 aa)
	PCSK9	Proprotein convertase subtilisin/kexin type 9. (693 aa)
	DGAT1	O-acyltransferase. (490 aa)
	PNPLA4	Patatin like phospholipase domain containing 4. (253 aa)
	LIPC	Lipase C, hepatic type. (463 aa)
	MTTP	Microsomal triglyceride transfer protein. (776 aa)
	LPIN3	Lipin 3. (851 aa)
	LIPG	Lipase G, endothelial type. (501 aa)
	INSIG1	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (261 aa)
	APOBR	Apolipoprotein B receptor. (996 aa)
	GPAM	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (787 aa)
	APOE	Apolipoprotein E. (314 aa)
	MOGAT2	Monoacylglycerol O-acyltransferase 2. (334 aa)
	PLB1	Phospholipase B1. (1454 aa)
	LIPH	Lipase H. (434 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACSL1	CPT1A	ENSPCOP00000014591	ENSPCOP00000000079	Acyl-CoA synthetase long chain family member 1.	Carnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family.	0.927
ACSL1	DGAT1	ENSPCOP00000014591	ENSPCOP00000016080	Acyl-CoA synthetase long chain family member 1.	O-acyltransferase.	0.457
ACSL1	DGAT2	ENSPCOP00000014591	ENSPCOP00000014732	Acyl-CoA synthetase long chain family member 1.	Diacylglycerol O-acyltransferase 2.	0.424
ACSL1	ENSPCOP00000007071	ENSPCOP00000014591	ENSPCOP00000007071	Acyl-CoA synthetase long chain family member 1.	Hydrolase_4 domain-containing protein.	0.860
ACSL1	GPAT3	ENSPCOP00000014591	ENSPCOP00000008803	Acyl-CoA synthetase long chain family member 1.	Glycerol-3-phosphate acyltransferase 3.	0.508
ACSL1	GPAT4	ENSPCOP00000014591	ENSPCOP00000020613	Acyl-CoA synthetase long chain family member 1.	Glycerol-3-phosphate acyltransferase 4.	0.642
ACSL1	LIPC	ENSPCOP00000014591	ENSPCOP00000016472	Acyl-CoA synthetase long chain family member 1.	Lipase C, hepatic type.	0.859
ACSL1	LIPE	ENSPCOP00000014591	ENSPCOP00000023030	Acyl-CoA synthetase long chain family member 1.	Lipase E, hormone sensitive type.	0.444
ACSL1	LIPF	ENSPCOP00000014591	ENSPCOP00000029512	Acyl-CoA synthetase long chain family member 1.	Lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.854
ACSL1	LIPG	ENSPCOP00000014591	ENSPCOP00000011908	Acyl-CoA synthetase long chain family member 1.	Lipase G, endothelial type.	0.862
ACSL1	LPGAT1	ENSPCOP00000014591	ENSPCOP00000008057	Acyl-CoA synthetase long chain family member 1.	Lysophosphatidylglycerol acyltransferase 1.	0.507
ACSL1	LPIN1	ENSPCOP00000014591	ENSPCOP00000015472	Acyl-CoA synthetase long chain family member 1.	Lipin 1.	0.418
ACSL1	LPL	ENSPCOP00000014591	ENSPCOP00000020759	Acyl-CoA synthetase long chain family member 1.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.882
ACSL1	PNPLA2	ENSPCOP00000014591	ENSPCOP00000006472	Acyl-CoA synthetase long chain family member 1.	Patatin like phospholipase domain containing 2.	0.856
ACSL1	PNPLA3	ENSPCOP00000014591	ENSPCOP00000002707	Acyl-CoA synthetase long chain family member 1.	Patatin like phospholipase domain containing 3.	0.875
ACSL1	PNPLA5	ENSPCOP00000014591	ENSPCOP00000008655	Acyl-CoA synthetase long chain family member 1.	Patatin like phospholipase domain containing 5.	0.708
ACSL1	SLC27A5	ENSPCOP00000014591	ENSPCOP00000012983	Acyl-CoA synthetase long chain family member 1.	Solute carrier family 27 member 5.	0.498
APOA5	APOB	ENSPCOP00000021758	ENSPCOP00000019340	Apolipoprotein A5.	Apolipoprotein B.	0.852
APOA5	APOE	ENSPCOP00000021758	ENSPCOP00000010240	Apolipoprotein A5.	Apolipoprotein E.	0.857
APOA5	GPIHBP1	ENSPCOP00000021758	ENSPCOP00000030547	Apolipoprotein A5.	Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1.	0.523