19 items (Propithecus coquereli) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SPR	Sepiapterin reductase. (261 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	TICAM1	TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (692 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
	NOS2	Nitric oxide synthase; Produces nitric oxide (NO). (1104 aa)
	RORA	RAR related orphan receptor A. (532 aa)
	CYP1B1	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
	MTARC1	MOSC domain-containing protein. (341 aa)
	GCHFR	GTP cyclohydrolase I feedback regulator. (84 aa)
	MARC2	Mitochondrial amidoxime reducing component 2. (335 aa)
	NOS1	Nitric oxide synthase; Produces nitric oxide (NO). (1434 aa)
	CYB5R3	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (320 aa)
	DDAH2	Dimethylarginine dimethylaminohydrolase 2. (285 aa)
	CYB5B	Cytochrome b5 type B; Belongs to the cytochrome b5 family. (148 aa)
	NOS3	Nitric oxide synthase 3. (994 aa)
	ACP5	Tartrate-resistant acid phosphatase type 5. (325 aa)
	ARG2	Arginase. (354 aa)
	GCH1	GTP cyclohydrolase 1. (250 aa)
	LOC105816653	C-type lectin domain-containing protein. (108 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACP5	ARG2	ENSPCOP00000004801	ENSPCOP00000003765	Tartrate-resistant acid phosphatase type 5.	Arginase.	0.432
ACP5	CYB5R3	ENSPCOP00000004801	ENSPCOP00000018167	Tartrate-resistant acid phosphatase type 5.	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.432
ACP5	GCH1	ENSPCOP00000004801	ENSPCOP00000001831	Tartrate-resistant acid phosphatase type 5.	GTP cyclohydrolase 1.	0.720
AKT1	CAV1	ENSPCOP00000028969	ENSPCOP00000025045	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.636
AKT1	NOS1	ENSPCOP00000028969	ENSPCOP00000019524	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Nitric oxide synthase; Produces nitric oxide (NO).	0.918
AKT1	NOS2	ENSPCOP00000028969	ENSPCOP00000024177	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Nitric oxide synthase; Produces nitric oxide (NO).	0.933
AKT1	NOS3	ENSPCOP00000028969	ENSPCOP00000009840	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Nitric oxide synthase 3.	0.980
AKT1	SPR	ENSPCOP00000028969	ENSPCOP00000002512	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Sepiapterin reductase.	0.715
ARG2	ACP5	ENSPCOP00000003765	ENSPCOP00000004801	Arginase.	Tartrate-resistant acid phosphatase type 5.	0.432
ARG2	CYB5R3	ENSPCOP00000003765	ENSPCOP00000018167	Arginase.	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.468
ARG2	DDAH2	ENSPCOP00000003765	ENSPCOP00000017618	Arginase.	Dimethylarginine dimethylaminohydrolase 2.	0.596
ARG2	NOS1	ENSPCOP00000003765	ENSPCOP00000019524	Arginase.	Nitric oxide synthase; Produces nitric oxide (NO).	0.900
ARG2	NOS2	ENSPCOP00000003765	ENSPCOP00000024177	Arginase.	Nitric oxide synthase; Produces nitric oxide (NO).	0.907
ARG2	NOS3	ENSPCOP00000003765	ENSPCOP00000009840	Arginase.	Nitric oxide synthase 3.	0.897
CAV1	AKT1	ENSPCOP00000025045	ENSPCOP00000028969	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.636
CAV1	NOS1	ENSPCOP00000025045	ENSPCOP00000019524	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Nitric oxide synthase; Produces nitric oxide (NO).	0.866
CAV1	NOS2	ENSPCOP00000025045	ENSPCOP00000024177	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Nitric oxide synthase; Produces nitric oxide (NO).	0.824
CAV1	NOS3	ENSPCOP00000025045	ENSPCOP00000009840	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Nitric oxide synthase 3.	0.940
CYB5B	CYB5R3	ENSPCOP00000016494	ENSPCOP00000018167	Cytochrome b5 type B; Belongs to the cytochrome b5 family.	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.941
CYB5B	MARC2	ENSPCOP00000016494	ENSPCOP00000019754	Cytochrome b5 type B; Belongs to the cytochrome b5 family.	Mitochondrial amidoxime reducing component 2.	0.681