STRINGSTRING
P2RX7 P2RX7 TRPV4 TRPV4 SLC12A9 SLC12A9 GNB3 GNB3 SLC12A4 SLC12A4 SLC12A8 SLC12A8 LRRC8E LRRC8E LRRC8A LRRC8A SCTR SCTR SHANK3 SHANK3 SLC12A6 SLC12A6 AQP1 AQP1 LOC105811124 LOC105811124 CLN3 CLN3 CLNS1A CLNS1A SLC12A5 SLC12A5 ANO6 ANO6 KCNN4 KCNN4 SLC12A2 SLC12A2 E2F4 E2F4 SLC12A1 SLC12A1 CCDC51 CCDC51 SLC12A3 SLC12A3 FSHR FSHR AQP11 AQP11 SCT SCT CLCN6 CLCN6 SLC12A7 SLC12A7 ENSPCOP00000022967 ENSPCOP00000022967 NPM1 NPM1 WNK3 WNK3 KCNMA1 KCNMA1 AQP4 AQP4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (870 aa)
SLC12A9Solute carrier family 12 member 9. (915 aa)
GNB3G protein subunit beta 3. (340 aa)
SLC12A4Solute carrier family 12 member 4. (1085 aa)
SLC12A8Solute carrier family 12 member 8. (714 aa)
LRRC8ELeucine rich repeat containing 8 VRAC subunit E. (795 aa)
LRRC8ALeucine rich repeat containing 8 VRAC subunit A. (810 aa)
SCTRSecretin receptor; Belongs to the G-protein coupled receptor 2 family. (445 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1726 aa)
SLC12A6Solute carrier family 12 member 6. (1145 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
LOC105811124Uncharacterized protein. (256 aa)
CLN3Battenin. (438 aa)
CLNS1AChloride nucleotide-sensitive channel 1A. (236 aa)
SLC12A5Solute carrier family 12 member 5. (1134 aa)
ANO6Anoctamin. (932 aa)
KCNN4Potassium calcium-activated channel subfamily N member 4. (427 aa)
SLC12A2Solute carrier family 12 member 2. (1153 aa)
E2F4E2F transcription factor 4. (408 aa)
SLC12A1Solute carrier family 12 member 1. (1099 aa)
CCDC51Coiled-coil domain containing 51. (410 aa)
SLC12A3Solute carrier family 12 member 3. (1027 aa)
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (695 aa)
AQP11Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (271 aa)
SCTSecretin. (132 aa)
CLCN6Chloride voltage-gated channel 6; Belongs to the chloride channel (TC 2.A.49) family. (929 aa)
SLC12A7Solute carrier family 12 member 7. (1041 aa)
ENSPCOP00000022967Uncharacterized protein. (277 aa)
NPM1Uncharacterized protein. (294 aa)
WNK3WNK lysine deficient protein kinase 3. (1791 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1286 aa)
AQP4Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family. (323 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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