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SLC9A1 SLC9A1 ATP1B2 ATP1B2 ADRA1A ADRA1A SHOX2 SHOX2 ADM5 ADM5 ATP1A2 ATP1A2 ANKRD28 ANKRD28 SCN10A SCN10A KCNH6 KCNH6 NPPA NPPA TNNI3K TNNI3K ANKRD44 ANKRD44 THRB THRB HEY2 HEY2 EDNRA EDNRA SCN1B SCN1B SNTA1 SNTA1 AGT AGT CSRP3 CSRP3 THRA THRA PDE5A PDE5A GRK2 GRK2 GJA1 GJA1 LOC105806374 LOC105806374 KCNJ2 KCNJ2 GATA4 GATA4 LOC105822688 LOC105822688 KCNH2 KCNH2 KCNN2 KCNN2 HRC HRC FXYD1 FXYD1 ENSPCOP00000027120 ENSPCOP00000027120 AGTR2 AGTR2 ENSPCOP00000026251 ENSPCOP00000026251 EDN3 EDN3 CHGA CHGA ACE2 ACE2 CAV1 CAV1 PDE4B PDE4B KCNIP2 KCNIP2 TH TH MYL4 MYL4 TNNT2 TNNT2 CACNA1H CACNA1H ADM ADM KCNE4 KCNE4 SREBF1 SREBF1 TACR3 TACR3 YWHAE YWHAE TRPV1 TRPV1 SLC8A2 SLC8A2 RANGRF RANGRF KCNJ3 KCNJ3 DSG2 DSG2 BVES BVES ADRA1D ADRA1D CTNNA3 CTNNA3 SPX SPX ATP2B2 ATP2B2 ASPH ASPH CAMK2D CAMK2D GLP1R GLP1R MEF2A MEF2A SCN4B SCN4B TMEM65 TMEM65 ATP2B3 ATP2B3 AKAP9 AKAP9 MYL10 MYL10 HCN3 HCN3 DMPK DMPK NOS1 NOS1 POPDC2 POPDC2 ATP1A3 ATP1A3 ENSPCOP00000018550 ENSPCOP00000018550 ADA ADA MYL2 MYL2 HCN2 HCN2 ANKRD66 ANKRD66 CACNB2 CACNB2 CACNA1G CACNA1G CACNA1C CACNA1C KCNQ1 KCNQ1 CXADR CXADR HOPX HOPX LOC105806372 LOC105806372 HSPB7 HSPB7 RNF207 RNF207 ANK2 ANK2 FOXN4 FOXN4 TNNI3 TNNI3 PIK3CG PIK3CG STC1 STC1 NKX2-5 NKX2-5 DLG1 DLG1 ATP2A2 ATP2A2 SLC8A3 SLC8A3 ENSPCOP00000014148 ENSPCOP00000014148 ATP2B4 ATP2B4 EDNRB EDNRB SLC4A3 SLC4A3 GSK3A GSK3A CACNA1D CACNA1D PDE4D PDE4D CCN2 CCN2 ATP2A3 ATP2A3 ISL1 ISL1 SLC8A1 SLC8A1 APELA APELA ADM2 ADM2 JUP JUP KCNJ5 KCNJ5 TBX5 TBX5 ATP1A1 ATP1A1 ATP1B1 ATP1B1 EDN2 EDN2 RGS2 RGS2 SCN2B SCN2B BIN1 BIN1 MYL3 MYL3 KCNG2 KCNG2 ADRA1B ADRA1B RYR2 RYR2 DES DES ZMPSTE24 ZMPSTE24 ASB3 ASB3 NOS3 NOS3 NOS1AP NOS1AP ENSPCOP00000009091 ENSPCOP00000009091 ZC3H12A ZC3H12A ENSPCOP00000008247 ENSPCOP00000008247 DSP DSP OXT OXT TMEM161B TMEM161B EDN1 EDN1 BMP10 BMP10 SCN5A SCN5A RNLS RNLS HBEGF HBEGF EPAS1 EPAS1 HCN4 HCN4 SLC1A1 SLC1A1 EHD3 EHD3 CACNA2D1 CACNA2D1 AVPR1A AVPR1A NUP155 NUP155 CAV3 CAV3 CLIC2 CLIC2 TRPC1 TRPC1 TBX2 TBX2 ATP2A1 ATP2A1 TMEM38B TMEM38B SPTBN4 SPTBN4 P2RX4 P2RX4 CHRM2 CHRM2 DRD2 DRD2 S100A1 S100A1 GJC1 GJC1 TMEM38A TMEM38A GCH1 GCH1 ATP2B1 ATP2B1 SRI SRI CASQ2 CASQ2 TGFB2 TGFB2 PKP2 PKP2 SMAD7 SMAD7 CORIN CORIN APLN APLN TRPM4 TRPM4 TMIGD3 TMIGD3
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
ADRA1AAdrenoceptor alpha 1A. (466 aa)
SHOX2Short stature homeobox 2. (355 aa)
ADM5Adrenomedullin 5 (putative). (134 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
ANKRD28Ankyrin repeat domain 28. (1083 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1958 aa)
KCNH6Potassium voltage-gated channel subfamily H member 6. (991 aa)
NPPANatriuretic peptide A. (153 aa)
TNNI3KUncharacterized protein. (724 aa)
ANKRD44Ankyrin repeat domain 44. (910 aa)
THRBThyroid hormone receptor beta. (476 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
SCN1BSodium voltage-gated channel beta subunit 1. (218 aa)
SNTA1Syntrophin alpha 1. (505 aa)
AGTAngiotensinogen; Belongs to the serpin family. (484 aa)
CSRP3Cysteine and glycine rich protein 3. (194 aa)
THRAThyroid hormone receptor alpha. (645 aa)
PDE5APhosphodiesterase. (839 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (689 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
LOC105806374Uncharacterized protein; Belongs to the cytochrome P450 family. (502 aa)
KCNJ2Potassium voltage-gated channel subfamily J member 2. (427 aa)
GATA4GATA binding protein 4. (445 aa)
LOC105822688Uncharacterized protein. (54 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2. (1148 aa)
KCNN2Potassium calcium-activated channel subfamily N member 2. (840 aa)
HRCHistidine rich calcium binding protein. (688 aa)
FXYD1FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (92 aa)
ENSPCOP00000027120Uncharacterized protein. (1243 aa)
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
ENSPCOP00000026251Glutaredoxin domain-containing protein. (175 aa)
EDN3Endothelin 3. (224 aa)
CHGAChromogranin A. (374 aa)
ACE2Angiotensin-converting enzyme. (805 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
PDE4BPhosphodiesterase. (567 aa)
KCNIP2Potassium voltage-gated channel interacting protein 2. (285 aa)
THTyrosine hydroxylase. (497 aa)
MYL4Myosin light chain 4. (195 aa)
TNNT2Troponin T2, cardiac type. (300 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2221 aa)
ADMAdrenomedullin. (182 aa)
KCNE4Potassium voltage-gated channel subfamily E regulatory subunit 4. (209 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1180 aa)
TACR3Tachykinin receptor 3; Belongs to the G-protein coupled receptor 1 family. (444 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (845 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (926 aa)
RANGRFRAN guanine nucleotide release factor. (186 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
DSG2Desmoglein 2. (1029 aa)
BVESBlood vessel epicardial substance. (360 aa)
ADRA1DAdrenoceptor alpha 1D. (577 aa)
CTNNA3Catenin alpha 3. (783 aa)
SPXSpexin hormone. (116 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
ASPHAspartate beta-hydroxylase. (687 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (503 aa)
GLP1RGlucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (451 aa)
MEF2AMyocyte enhancer factor 2A. (495 aa)
SCN4BSodium voltage-gated channel beta subunit 4. (225 aa)
TMEM65Transmembrane protein 65. (234 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
AKAP9A-kinase anchoring protein 9. (3687 aa)
MYL10Myosin light chain 10. (147 aa)
HCN3Hyperpolarization activated cyclic nucleotide gated potassium channel 3. (779 aa)
DMPKDM1 protein kinase. (630 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1434 aa)
POPDC2Popeye domain containing 2. (357 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (1080 aa)
ENSPCOP00000018550Uncharacterized protein. (317 aa)
ADAAdenosine deaminase. (363 aa)
MYL2Myosin light chain 2. (166 aa)
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (816 aa)
ANKRD66Ankyrin repeat domain 66. (238 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (660 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2381 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2016 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (545 aa)
CXADRUncharacterized protein. (352 aa)
HOPXHomeobox domain-containing protein. (76 aa)
LOC105806372Uncharacterized protein; Belongs to the cytochrome P450 family. (502 aa)
HSPB7Heat shock protein family B (small) member 7; Belongs to the small heat shock protein (HSP20) family. (169 aa)
RNF207Ring finger protein 207. (634 aa)
ANK2Ankyrin 2. (3925 aa)
FOXN4Forkhead box N4. (517 aa)
TNNI3Troponin I3, cardiac type. (211 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
STC1Stanniocalcin 1. (247 aa)
NKX2-5NK2 homeobox 5. (324 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (910 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa)
ENSPCOP00000014148Uncharacterized protein. (733 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1204 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (485 aa)
SLC4A3Anion exchange protein. (1233 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (483 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2180 aa)
PDE4DPhosphodiesterase. (667 aa)
CCN2Cellular communication network factor 2. (347 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1033 aa)
ISL1ISL LIM homeobox 1. (349 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (974 aa)
APELAApelin receptor early endogenous ligand. (54 aa)
ADM2Adrenomedullin 2. (148 aa)
JUPJunction plakoglobin. (745 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
TBX5T-box transcription factor 5. (518 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1023 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
EDN2Endothelin 2. (178 aa)
RGS2Regulator of G protein signaling 2. (211 aa)
SCN2BSodium voltage-gated channel beta subunit 2. (215 aa)
BIN1Bridging integrator 1. (594 aa)
MYL3Myosin light chain 3. (197 aa)
KCNG2Potassium voltage-gated channel modifier subfamily G member 2; Belongs to the potassium channel family. (428 aa)
ADRA1BAdrenoceptor alpha 1B. (518 aa)
RYR2Ryanodine receptor 2. (4825 aa)
DESDesmin; Belongs to the intermediate filament family. (470 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
ASB3Ankyrin repeat and SOCS box containing 3. (473 aa)
NOS3Nitric oxide synthase 3. (994 aa)
NOS1APNitric oxide synthase 1 adaptor protein. (507 aa)
ENSPCOP00000009091Uncharacterized protein. (291 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (598 aa)
ENSPCOP00000008247Uncharacterized protein. (164 aa)
DSPDesmoplakin. (2868 aa)
OXTOxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family. (125 aa)
TMEM161BTransmembrane protein 161B. (471 aa)
EDN1Endothelin 1. (193 aa)
BMP10Bone morphogenetic protein 10. (423 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2017 aa)
RNLSRenalase, FAD dependent amine oxidase. (342 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
EPAS1Endothelial PAS domain protein 1. (869 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1199 aa)
SLC1A1Amino acid transporter. (524 aa)
EHD3EH domain containing 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (535 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (740 aa)
AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (410 aa)
NUP155Nucleoporin 155. (1218 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
CLIC2Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (247 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (842 aa)
TBX2T-box transcription factor 2. (713 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1028 aa)
TMEM38BTransmembrane protein 38B. (291 aa)
SPTBN4Spectrin beta chain; Belongs to the spectrin family. (2533 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (402 aa)
CHRM2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
S100A1Protein S100; Belongs to the S-100 family. (139 aa)
GJC1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (396 aa)
TMEM38ATransmembrane protein 38A. (303 aa)
GCH1GTP cyclohydrolase 1. (250 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1258 aa)
SRISorcin. (198 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (398 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
PKP2Plakophilin 2. (838 aa)
SMAD7Mothers against decapentaplegic homolog. (490 aa)
CORINCorin, serine peptidase. (1042 aa)
APLNApelin. (77 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1204 aa)
TMIGD3Transmembrane and immunoglobulin domain containing 3; Belongs to the G-protein coupled receptor 1 family. (347 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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