STRINGSTRING
TEX11 TEX11 TLR3 TLR3 AGO4 AGO4 GATA3 GATA3 KDM5A KDM5A SOX15 SOX15 HOXA10 HOXA10 WNT5A WNT5A SGPL1 SGPL1 RHOBTB3 RHOBTB3 FGF9 FGF9 NUDT1 NUDT1 ARID4A ARID4A MSH2 MSH2 ASPM ASPM BOK BOK NUP210L NUP210L RAB13 RAB13 RXFP2 RXFP2 YBX3 YBX3 NR0B1 NR0B1 ARID5B ARID5B NCOA4 NCOA4 ENSPCOP00000002686 ENSPCOP00000002686 LRP2 LRP2 TFAP2C TFAP2C DMRT1 DMRT1 TGFB2 TGFB2 ADGRG1 ADGRG1 HMGA2 HMGA2 WNT2B WNT2B DHH DHH SRD5A2 SRD5A2 SCX SCX ARID4B ARID4B KLHL10 KLHL10 SIX4 SIX4 SDC1 SDC1 ENSPCOP00000023926 ENSPCOP00000023926 TNFSF10 TNFSF10 RARA RARA KIT KIT GFRA1 GFRA1 ESR1 ESR1 ACE ACE SAFB2 SAFB2 KITLG KITLG CYP1B1 CYP1B1 CITED2 CITED2 SOX8 SOX8 WNT4 WNT4 LHCGR LHCGR BCL2 BCL2 BCL2L1 BCL2L1 LHX9 LHX9 FSHR FSHR KIF18A KIF18A GATA1 GATA1 BAX BAX PRDX4 PRDX4 INHBA INHBA SFRP2 SFRP2 TGFBR1 TGFBR1 INHA INHA ING2 ING2 WT1 WT1 TFPT TFPT FANCA FANCA PATZ1 PATZ1 ATRX ATRX MAMLD1 MAMLD1 BIK BIK HOXA11 HOXA11 INHBB INHBB FER FER FSHB FSHB REC8 REC8 UTF1 UTF1 TMF1 TMF1 CSDE1 CSDE1 AMHR2 AMHR2 CSMD1 CSMD1 NASP NASP CBL CBL NTRK1 NTRK1 ACVR2A ACVR2A FNDC3A FNDC3A TBC1D20 TBC1D20 SPATA2 SPATA2 SOX9 SOX9 PLEKHA1 PLEKHA1 AMH AMH GATA4 GATA4 GATA6 GATA6 RUSC1 RUSC1 NHLH2 NHLH2 NR5A1 NR5A1 CSMD2 CSMD2 NKX3-1 NKX3-1 ATN1 ATN1 ADAM15 ADAM15 SMAD4 SMAD4 PDGFA PDGFA BCL2L11 BCL2L11 AR AR ERCC1 ERCC1 HSD17B4 HSD17B4 TCF21 TCF21 TESC TESC PDGFRB PDGFRB CTNNA1 CTNNA1 SFRP1 SFRP1 SCAPER SCAPER NKX2-1 NKX2-1 CRKL CRKL REN REN RNF38 RNF38 SF1 SF1 LRRC6 LRRC6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TEX11Testis expressed 11. (895 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (905 aa)
AGO4Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (855 aa)
GATA3Uncharacterized protein. (444 aa)
KDM5ALysine demethylase 5A. (1483 aa)
SOX15SRY-box transcription factor 15. (233 aa)
HOXA10Homeobox A10. (410 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (560 aa)
RHOBTB3Rho related BTB domain containing 3. (548 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
NUDT1Nudix hydrolase 1. (156 aa)
ARID4AAT-rich interaction domain 4A. (1267 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (868 aa)
ASPMAbnormal spindle microtubule assembly. (3472 aa)
BOKBCL2 family apoptosis regulator BOK. (213 aa)
NUP210LNucleoporin 210 like. (1816 aa)
RAB13Uncharacterized protein. (202 aa)
RXFP2Relaxin family peptide receptor 2. (753 aa)
YBX3Y-box binding protein 3. (242 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (468 aa)
ARID5BAT-rich interaction domain 5B. (1188 aa)
NCOA4Nuclear receptor coactivator 4. (650 aa)
ENSPCOP00000002686CSD_1 domain-containing protein. (293 aa)
LRP2LDL receptor related protein 2. (4654 aa)
TFAP2CTranscription factor AP-2 gamma. (450 aa)
DMRT1Doublesex and mab-3 related transcription factor 1. (375 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
ADGRG1Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (697 aa)
HMGA2Uncharacterized protein. (117 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
DHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa)
SRD5A2Steroid 5 alpha-reductase 2. (238 aa)
SCXScleraxis bHLH transcription factor. (208 aa)
ARID4BAT-rich interaction domain 4B. (1315 aa)
KLHL10Kelch like family member 10. (608 aa)
SIX4SIX homeobox 4. (782 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (310 aa)
ENSPCOP00000023926Uncharacterized protein. (364 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (288 aa)
RARARetinoic acid receptor alpha. (472 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
GFRA1GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Belongs to the GDNFR family. (468 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (599 aa)
ACEAngiotensin-converting enzyme. (1308 aa)
SAFB2Scaffold attachment factor B2. (923 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa)
SOX8SRY-box transcription factor 8. (462 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (701 aa)
BCL2BCL2 apoptosis regulator. (234 aa)
BCL2L1BCL2 like 1. (233 aa)
LHX9LIM homeobox 9. (398 aa)
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (695 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (843 aa)
GATA1GATA binding protein 1. (413 aa)
BAXBCL2 associated X, apoptosis regulator. (199 aa)
PRDX4Peroxiredoxin 4. (272 aa)
INHBAInhibin subunit beta A. (426 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (421 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (368 aa)
ING2Inhibitor of growth protein. (281 aa)
WT1WT1 transcription factor. (522 aa)
TFPTTCF3 fusion partner. (253 aa)
FANCAFA complementation group A. (1362 aa)
PATZ1POZ/BTB and AT hook containing zinc finger 1. (695 aa)
ATRXATRX chromatin remodeler. (2447 aa)
MAMLD1Mastermind like domain containing 1. (985 aa)
BIKBCL2 interacting killer. (152 aa)
HOXA11Homeobox A11. (316 aa)
INHBBInhibin subunit beta B. (408 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
FSHBFollicle stimulating hormone subunit beta. (129 aa)
REC8REC8 meiotic recombination protein. (560 aa)
UTF1Undifferentiated embryonic cell transcription factor 1. (343 aa)
TMF1TATA element modulatory factor 1. (780 aa)
CSDE1Cold shock domain containing E1. (798 aa)
AMHR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (476 aa)
CSMD1CUB and Sushi multiple domains 1. (3147 aa)
NASPNuclear autoantigenic sperm protein. (695 aa)
CBLCbl proto-oncogene. (891 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (416 aa)
FNDC3AFibronectin type III domain containing 3A. (1044 aa)
TBC1D20TBC1 domain family member 20. (403 aa)
SPATA2Spermatogenesis associated 2. (520 aa)
SOX9SRY-box transcription factor 9. (505 aa)
PLEKHA1Pleckstrin homology domain containing A1. (400 aa)
AMHAnti-Mullerian hormone. (561 aa)
GATA4GATA binding protein 4. (445 aa)
GATA6GATA binding protein 6. (593 aa)
RUSC1RUN and SH3 domain containing 1. (903 aa)
NHLH2Nescient helix-loop-helix 2. (135 aa)
NR5A1Nuclear receptor subfamily 5 group A member 1. (461 aa)
CSMD2CUB and Sushi multiple domains 2. (3597 aa)
NKX3-1NK3 homeobox 1. (226 aa)
ATN1Atrophin 1. (1192 aa)
ADAM15ADAM metallopeptidase domain 15. (859 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa)
BCL2L11BCL2 like 11. (200 aa)
ARAndrogen receptor. (886 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (298 aa)
HSD17B4Hydroxysteroid 17-beta dehydrogenase 4. (705 aa)
TCF21Transcription factor 21. (179 aa)
TESCTescalcin. (236 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1105 aa)
CTNNA1Catenin alpha 1. (906 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
SCAPERS-phase cyclin A associated protein in the ER. (1400 aa)
NKX2-1NK2 homeobox 1. (401 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
RENRenin; Belongs to the peptidase A1 family. (405 aa)
RNF38Ring finger protein 38. (516 aa)
SF1Splicing factor 1. (647 aa)
LRRC6Leucine rich repeat containing 6. (409 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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