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AHCYL1 AHCYL1 PKP2 PKP2 WNK1 WNK1 WNK4 WNK4 FXYD2 FXYD2 SCN5A SCN5A MLLT6 MLLT6 ATP1B1 ATP1B1 ENSPCOP00000014148 ENSPCOP00000014148 FGF12 FGF12 NKX2-5 NKX2-5 ANK3 ANK3 CNTN1 CNTN1 GLRX GLRX ATP1B3 ATP1B3 NOS1 NOS1 CHP1 CHP1 SCN4B SCN4B WNK3 WNK3 PRSS8 PRSS8 WNK2 WNK2 DNM2 DNM2 ENSPCOP00000027120 ENSPCOP00000027120 FXYD1 FXYD1 DRD4 DRD4 AKT1 AKT1 CHP2 CHP2 TESC TESC SLC9A1 SLC9A1 ATP1B2 ATP1B2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
PKP2Plakophilin 2. (838 aa)
WNK1WNK lysine deficient protein kinase 1. (2808 aa)
WNK4WNK lysine deficient protein kinase 4. (1242 aa)
FXYD2FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (66 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2017 aa)
MLLT6MLLT6, PHD finger containing. (1092 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
ENSPCOP00000014148Uncharacterized protein. (733 aa)
FGF12Fibroblast growth factor 12; Belongs to the heparin-binding growth factors family. (208 aa)
NKX2-5NK2 homeobox 5. (324 aa)
ANK3Ankyrin 3. (4372 aa)
CNTN1Contactin 1. (1018 aa)
GLRXGlutaredoxin. (106 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1434 aa)
CHP1Calcineurin like EF-hand protein 1. (201 aa)
SCN4BSodium voltage-gated channel beta subunit 4. (225 aa)
WNK3WNK lysine deficient protein kinase 3. (1791 aa)
PRSS8Serine protease 8; Belongs to the peptidase S1 family. (341 aa)
WNK2WNK lysine deficient protein kinase 2. (2211 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
ENSPCOP00000027120Uncharacterized protein. (1243 aa)
FXYD1FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (92 aa)
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (333 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
CHP2Calcineurin like EF-hand protein 2. (196 aa)
TESCTescalcin. (236 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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