STRINGSTRING
SERPINE2 SERPINE2 WNK3 WNK3 COMMD1 COMMD1 GRP GRP WNK1 WNK1 WNK2 WNK2 WNK4 WNK4 OSR1 OSR1 PRKCE PRKCE NEDD4 NEDD4 HECW2 HECW2 STK39 STK39 HECW1 HECW1 PCSK9 PCSK9 CAMK2D CAMK2D
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SERPINE2Serpin family E member 2; Belongs to the serpin family. (409 aa)
WNK3WNK lysine deficient protein kinase 3. (1791 aa)
COMMD1Copper metabolism domain containing 1. (189 aa)
GRPGastrin releasing peptide. (137 aa)
WNK1WNK lysine deficient protein kinase 1. (2808 aa)
WNK2WNK lysine deficient protein kinase 2. (2211 aa)
WNK4WNK lysine deficient protein kinase 4. (1242 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
NEDD4NEDD4 E3 ubiquitin protein ligase. (1320 aa)
HECW2HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2. (1520 aa)
STK39Serine/threonine kinase 39. (522 aa)
HECW1HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1. (1600 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9. (693 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (503 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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