STRINGSTRING
ALOX15 ALOX15 ABI3BP ABI3BP CCL21 CCL21 MYOC MYOC ARPC2 ARPC2 PRKCZ PRKCZ LIMS2 LIMS2 TSC1 TSC1 LOC105822640 LOC105822640 CCL28 CCL28 ENSPCOP00000002927 ENSPCOP00000002927 C1QBP C1QBP NID1 NID1 HPSE HPSE MAP4K4 MAP4K4 ENSPCOP00000030822 ENSPCOP00000030822 SFRP1 SFRP1 ENSPCOP00000030414 ENSPCOP00000030414 CRKL CRKL LIMS1 LIMS1 ARHGEF7 ARHGEF7 HRG HRG CALR CALR TSTA3 TSTA3 UNC13D UNC13D PTK2B PTK2B ENSPCOP00000027120 ENSPCOP00000027120 CDK6 CDK6 PRKCE PRKCE EPHA1 EPHA1 DNM2 DNM2 EGFL6 EGFL6 ECM2 ECM2 RSU1 RSU1 FN1 FN1 BRAF BRAF FERMT1 FERMT1 VEGFA VEGFA ITGA3 ITGA3 FGA FGA DAG1 DAG1 EMILIN1 EMILIN1 DMP1 DMP1 GSK3B GSK3B ITGB1BP1 ITGB1BP1 ENSPCOP00000022492 ENSPCOP00000022492 ENSPCOP00000022475 ENSPCOP00000022475 CDC42 CDC42 PLEKHA2 PLEKHA2 SDC4 SDC4 EFEMP2 EFEMP2 SMAD3 SMAD3 PREX1 PREX1 RIN2 RIN2 WNT4 WNT4 DAB2 DAB2 CX3CL1 CX3CL1 SKAP1 SKAP1 ENSPCOP00000020279 ENSPCOP00000020279 SPOCK2 SPOCK2 FBLN1 FBLN1 PDGFB PDGFB POLDIP2 POLDIP2 ARL2 ARL2 COL8A1 COL8A1 CARMIL1 CARMIL1 CRK CRK CCN1 CCN1 FBLN2 FBLN2 AGR2 AGR2 LRRC45 LRRC45 NRP1 NRP1 CCDC80 CCDC80 VIT VIT CASS4 CASS4 CCL25 CCL25 EGFLAM EGFLAM ENSPCOP00000014532 ENSPCOP00000014532 CSPG5 CSPG5 EPB41L5 EPB41L5 HAS2 HAS2 HACD1 HACD1 COL16A1 COL16A1 STK4 STK4 ENSPCOP00000014148 ENSPCOP00000014148 P4HB P4HB DMTN DMTN COL26A1 COL26A1 ENSPCOP00000013694 ENSPCOP00000013694 FGG FGG RRAS RRAS RELL2 RELL2 PTPRJ PTPRJ JUP JUP NEDD9 NEDD9 MDK MDK FERMT2 FERMT2 OLFM4 OLFM4 ENSPCOP00000011221 ENSPCOP00000011221 CD3E CD3E CD36 CD36 CCR7 CCR7 EMID1 EMID1 DOCK5 DOCK5 FLNA FLNA HSD17B12 HSD17B12 THY1 THY1 ENSPCOP00000009506 ENSPCOP00000009506 FOXF1 FOXF1 TEK TEK NINJ1 NINJ1 ROCK1 ROCK1 FGB FGB S100A10 S100A10 CIB1 CIB1 TRIOBP TRIOBP TESK1 TESK1 KDR KDR ENSPCOP00000005855 ENSPCOP00000005855 ITGA5 ITGA5 CSF1 CSF1 VWC2 VWC2 EMP2 EMP2 RREB1 RREB1 PPM1F PPM1F
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ALOX15Arachidonate 15-lipoxygenase. (663 aa)
ABI3BPABI family member 3 binding protein. (1756 aa)
CCL21C-C motif chemokine ligand 21. (131 aa)
MYOCMyocilin. (504 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (292 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
LIMS2LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (366 aa)
TSC1TSC complex subunit 1. (1164 aa)
LOC105822640Integrin beta; Belongs to the integrin beta chain family. (454 aa)
CCL28C-C motif chemokine. (127 aa)
ENSPCOP00000002927Uncharacterized protein. (160 aa)
C1QBPUncharacterized protein. (281 aa)
NID1Nidogen 1. (1248 aa)
HPSEHeparanase. (395 aa)
MAP4K4Mitogen-activated protein kinase kinase kinase kinase 4. (1352 aa)
ENSPCOP00000030822Uncharacterized protein. (911 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
ENSPCOP00000030414Uncharacterized protein. (347 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
LIMS1LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (398 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (782 aa)
HRGHistidine rich glycoprotein. (468 aa)
CALRCalreticulin. (417 aa)
TSTA3Tissue specific transplantation antigen P35B. (321 aa)
UNC13DUnc-13 homolog D. (1109 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (967 aa)
ENSPCOP00000027120Uncharacterized protein. (1243 aa)
CDK6Cyclin dependent kinase 6. (263 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
EPHA1EPH receptor A1. (942 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
EGFL6EGF like domain multiple 6. (554 aa)
ECM2Extracellular matrix protein 2. (700 aa)
RSU1Ras suppressor protein 1. (277 aa)
FN1Fibronectin 1. (2290 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (745 aa)
FERMT1Fermitin family member 1. (677 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1066 aa)
FGAFib_alpha domain-containing protein. (649 aa)
DAG1Dystroglycan 1. (895 aa)
EMILIN1Elastin microfibril interfacer 1. (1022 aa)
DMP1Dentin matrix acidic phosphoprotein 1. (509 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (390 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
ENSPCOP00000022492Uncharacterized protein. (356 aa)
ENSPCOP00000022475Uncharacterized protein. (173 aa)
CDC42Uncharacterized protein. (191 aa)
PLEKHA2Pleckstrin homology domain containing A2. (425 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (200 aa)
EFEMP2EGF containing fibulin extracellular matrix protein 2. (443 aa)
SMAD3Mothers against decapentaplegic homolog. (443 aa)
PREX1Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1626 aa)
RIN2Ras and Rab interactor 2. (924 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
DAB2DAB adaptor protein 2. (769 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (405 aa)
SKAP1Src kinase associated phosphoprotein 1. (358 aa)
ENSPCOP00000020279Calponin-homology (CH) domain-containing protein. (425 aa)
SPOCK2SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2. (424 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (723 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
POLDIP2DNA polymerase delta interacting protein 2. (368 aa)
ARL2ADP ribosylation factor like GTPase 2; Belongs to the small GTPase superfamily. Arf family. (184 aa)
COL8A1Collagen type VIII alpha 1 chain. (744 aa)
CARMIL1Capping protein regulator and myosin 1 linker 1. (1332 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
CCN1Cellular communication network factor 1. (381 aa)
FBLN2Fibulin 2. (1224 aa)
AGR2Anterior gradient 2, protein disulphide isomerase family member. (122 aa)
LRRC45Leucine rich repeat containing 45. (655 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
CCDC80Coiled-coil domain containing 80. (948 aa)
VITVitrin. (693 aa)
CASS4Cas scaffold protein family member 4. (774 aa)
CCL25SCY domain-containing protein. (109 aa)
EGFLAMEGF like, fibronectin type III and laminin G domains. (1017 aa)
ENSPCOP00000014532S_100 domain-containing protein; Belongs to the S-100 family. (88 aa)
CSPG5Chondroitin sulfate proteoglycan 5. (566 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (731 aa)
HAS2Hyaluronan synthase 2. (552 aa)
HACD1Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (235 aa)
COL16A1Collagen type XVI alpha 1 chain. (1610 aa)
STK4Serine/threonine kinase 4. (487 aa)
ENSPCOP00000014148Uncharacterized protein. (733 aa)
P4HBProtein disulfide-isomerase. (510 aa)
DMTNDematin actin binding protein. (412 aa)
COL26A1Collagen type XXVI alpha 1 chain. (441 aa)
ENSPCOP00000013694Uncharacterized protein. (199 aa)
FGGFibrinogen gamma chain. (456 aa)
RRASRAS related. (220 aa)
RELL2RELT like 2. (303 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1223 aa)
JUPJunction plakoglobin. (745 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (834 aa)
MDKMidkine. (143 aa)
FERMT2Fermitin family member 2. (693 aa)
OLFM4Olfactomedin 4. (498 aa)
ENSPCOP00000011221FERM domain-containing protein. (471 aa)
CD3ECD3e molecule. (187 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
EMID1EMI domain containing 1. (430 aa)
DOCK5Dedicator of cytokinesis 5; Belongs to the DOCK family. (1723 aa)
FLNAFilamin A. (2647 aa)
HSD17B12Hydroxysteroid 17-beta dehydrogenase 12. (276 aa)
THY1Thy-1 cell surface antigen. (161 aa)
ENSPCOP00000009506Uncharacterized protein. (103 aa)
FOXF1Forkhead box F1. (381 aa)
TEKTEK receptor tyrosine kinase. (1125 aa)
NINJ1Ninjurin 1. (152 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1316 aa)
FGBFibrinogen beta chain. (492 aa)
S100A10S_100 domain-containing protein; Belongs to the S-100 family. (97 aa)
CIB1Calcium and integrin binding 1. (191 aa)
TRIOBPPH domain-containing protein. (647 aa)
TESK1Testis associated actin remodelling kinase 1. (628 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
ENSPCOP00000005855Uncharacterized protein. (259 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1041 aa)
CSF1Colony stimulating factor 1. (438 aa)
VWC2Von Willebrand factor C domain containing 2. (325 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
RREB1Ras responsive element binding protein 1. (1731 aa)
PPM1FProtein phosphatase, Mg2+/Mn2+ dependent 1F. (444 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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