STRINGSTRING
RNF126 RNF126 DENND10 DENND10 ARF6 ARF6 ALS2CL ALS2CL SLC66A2 SLC66A2 AP3B1 AP3B1 DENND1C DENND1C SNX8 SNX8 VPS4A VPS4A SNX17 SNX17 LOC105806099 LOC105806099 ARHGAP44 ARHGAP44 WASHC3 WASHC3 GOLT1A GOLT1A CLTC CLTC AP5Z1 AP5Z1 EHD2 EHD2 EHD1 EHD1 ARL1 ARL1 REPS1 REPS1 RAB11FIP3 RAB11FIP3 TBC1D10A TBC1D10A RAB13 RAB13 REPS2 REPS2 BTBD8 BTBD8 DENND2A DENND2A VAMP4 VAMP4 VPS37B VPS37B EPS15 EPS15 LEPROTL1 LEPROTL1 CCDC93 CCDC93 SNX6 SNX6 CLEC16A CLEC16A RAB7A RAB7A GOLT1B GOLT1B ANKRD27 ANKRD27 EIPR1 EIPR1 ANKRD63 ANKRD63 MYO5B MYO5B EHD3 EHD3 ENSPCOP00000005363 ENSPCOP00000005363 EVI5 EVI5 RGP1 RGP1 VPS39 VPS39 TBC1D23 TBC1D23 VPS35L VPS35L LOC105823447 LOC105823447 AP5S1 AP5S1 VAMP3 VAMP3 RHOBTB3 RHOBTB3 TMEM50A TMEM50A ABCA1 ABCA1 RIC1 RIC1 ENSPCOP00000007709 ENSPCOP00000007709 TOM1 TOM1 NSG1 NSG1 RASSF9 RASSF9 STAM STAM VTI1A VTI1A ATP6AP1 ATP6AP1 ENSPCOP00000008533 ENSPCOP00000008533 TRARG1 TRARG1 STX6 STX6 STAM2 STAM2 SORT1 SORT1 GRIP2 GRIP2 ENSPCOP00000009180 ENSPCOP00000009180 SNX12 SNX12 TBC1D17 TBC1D17 HGS HGS RAB17 RAB17 VTI1B VTI1B YKT6 YKT6 TMEM87B TMEM87B DCLK1 DCLK1 LOC105821613 LOC105821613 VPS35 VPS35 CMTM6 CMTM6 CHMP2A CHMP2A PHETA1 PHETA1 MVB12A MVB12A VTA1 VTA1 RAB14 RAB14 ENSPCOP00000012420 ENSPCOP00000012420 ENSPCOP00000012421 ENSPCOP00000012421 MVB12B MVB12B TRIM27 TRIM27 ENTR1 ENTR1 VPS26A VPS26A AP5B1 AP5B1 VPS29 VPS29 LOC105821645 LOC105821645 LAPTM4A LAPTM4A ENSPCOP00000014900 ENSPCOP00000014900 LAMTOR1 LAMTOR1 CHMP4B CHMP4B RAB7B RAB7B CALY CALY VPS25 VPS25 NSG2 NSG2 LYST LYST ENSPCOP00000016411 ENSPCOP00000016411 DENND5A DENND5A CLTCL1 CLTCL1 VCP VCP GRIPAP1 GRIPAP1 ARHGAP1 ARHGAP1 CRACR2A CRACR2A SNX30 SNX30 DPY30 DPY30 TBC1D5 TBC1D5 SNX32 SNX32 ERC1 ERC1 GRIP1 GRIP1 AP5M1 AP5M1 ITSN1 ITSN1 ANKRD50 ANKRD50 BAIAP3 BAIAP3 VPS54 VPS54 DCTN1 DCTN1 TMEM87A TMEM87A CHMP4C CHMP4C MICALL2 MICALL2 TBC1D10C TBC1D10C PIKFYVE PIKFYVE TBC1D10B TBC1D10B TSG101 TSG101 MICALL1 MICALL1 VPS36 VPS36 SNX2 SNX2 TINAGL1 TINAGL1 ENSPCOP00000020579 ENSPCOP00000020579 LOC105821266 LOC105821266 SNX18 SNX18 SCRIB SCRIB TBC1D14 TBC1D14 LOC105823974 LOC105823974 HEATR5A HEATR5A AGAP2 AGAP2 KIAA1109 KIAA1109 SNX1 SNX1 ITSN2 ITSN2 SRL SRL UBE2O UBE2O ZFYVE16 ZFYVE16 SNX4 SNX4 ENSPCOP00000022489 ENSPCOP00000022489 CCDC22 CCDC22 VPS50 VPS50 ACAP2 ACAP2 SNX33 SNX33 SPAG9 SPAG9 EHD4 EHD4 ENSPCOP00000023416 ENSPCOP00000023416 CORO1C CORO1C SNX27 SNX27 AP3D1 AP3D1 ARFRP1 ARFRP1 LAPTM4B LAPTM4B TMEM50B TMEM50B PREPL PREPL STX16 STX16 STX5 STX5 VPS28 VPS28 LMTK2 LMTK2 GCC2 GCC2 ENSPCOP00000025823 ENSPCOP00000025823 DENND1A DENND1A DENND1B DENND1B PLEKHJ1 PLEKHJ1 ANKFY1 ANKFY1 ALS2 ALS2 RAB35 RAB35 SGSM2 SGSM2 EPG5 EPG5 RAB10 RAB10 GGA1 GGA1 SNF8 SNF8 LEPROT LEPROT RAB29 RAB29 GBF1 GBF1 VPS26C VPS26C RAB11FIP4 RAB11FIP4 STX10 STX10 UBXN6 UBXN6 LRRC1 LRRC1 VPS51 VPS51 SNX9 SNX9 LOC105825493 LOC105825493 VPS52 VPS52 VPS16 VPS16 RILP RILP ZFYVE9 ZFYVE9 ARL4C ARL4C VPS53 VPS53 HEATR5B HEATR5B VPS26B VPS26B PTPN23 PTPN23 GGA3 GGA3 WAS WAS EPS15L1 EPS15L1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RNF126Ring finger protein 126. (268 aa)
DENND10DENN domain containing 10. (357 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
ALS2CLALS2 C-terminal like. (958 aa)
SLC66A2Uncharacterized protein. (271 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (958 aa)
DENND1CDENN domain containing 1C. (797 aa)
SNX8Sorting nexin 8. (433 aa)
VPS4AUncharacterized protein; Belongs to the AAA ATPase family. (504 aa)
SNX17Sorting nexin 17. (470 aa)
LOC105806099WH2 domain-containing protein. (466 aa)
ARHGAP44Rho GTPase activating protein 44. (766 aa)
WASHC3WASH complex subunit 3. (194 aa)
GOLT1AGolgi transport 1A. (132 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1681 aa)
AP5Z1Adaptor related protein complex 5 subunit zeta 1. (807 aa)
EHD2EH domain containing 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (543 aa)
EHD1EH domain containing 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (551 aa)
ARL1Uncharacterized protein. (157 aa)
REPS1RALBP1 associated Eps domain containing 1. (796 aa)
RAB11FIP3RAB11 family interacting protein 3. (720 aa)
TBC1D10ATBC1 domain family member 10A. (499 aa)
RAB13Uncharacterized protein. (202 aa)
REPS2RALBP1 associated Eps domain containing 2. (649 aa)
BTBD8BTB domain containing 8. (1406 aa)
DENND2ADENN domain containing 2A. (926 aa)
VAMP4Vesicle associated membrane protein 4. (141 aa)
VPS37BVPS37B subunit of ESCRT-I. (285 aa)
EPS15Uncharacterized protein. (842 aa)
LEPROTL1Leptin receptor overlapping transcript like 1. (145 aa)
CCDC93Coiled-coil domain containing 93. (579 aa)
SNX6Sorting nexin; Involved in several stages of intracellular trafficking. (418 aa)
CLEC16AC-type lectin domain containing 16A. (1053 aa)
RAB7ARAB7A, member RAS oncogene family. (161 aa)
GOLT1BGolgi transport 1B. (144 aa)
ANKRD27Ankyrin repeat domain 27. (1050 aa)
EIPR1EARP complex and GARP complex interacting protein 1. (387 aa)
ANKRD63Ankyrin repeat domain 63. (381 aa)
MYO5BUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1731 aa)
EHD3EH domain containing 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (535 aa)
ENSPCOP00000005363Uncharacterized protein. (203 aa)
EVI5Ecotropic viral integration site 5. (820 aa)
RGP1RGP1 homolog, RAB6A GEF complex partner 1. (391 aa)
VPS39VPS39 subunit of HOPS complex. (852 aa)
TBC1D23TBC1 domain family member 23. (601 aa)
VPS35LVPS35 endosomal protein sorting factor like. (896 aa)
LOC105823447Uncharacterized protein. (594 aa)
AP5S1Adaptor related protein complex 5 subunit sigma 1. (200 aa)
VAMP3V-SNARE coiled-coil homology domain-containing protein. (104 aa)
RHOBTB3Rho related BTB domain containing 3. (548 aa)
TMEM50ATransmembrane protein 50A. (157 aa)
ABCA1ATP binding cassette subfamily A member 1. (2240 aa)
RIC1RIC1 homolog, RAB6A GEF complex partner 1. (1226 aa)
ENSPCOP00000007709Uncharacterized protein. (186 aa)
TOM1Target of myb1 membrane trafficking protein; Belongs to the TOM1 family. (492 aa)
NSG1Neuronal vesicle trafficking associated 1. (185 aa)
RASSF9Ras association domain family member 9. (435 aa)
STAMVHS domain-containing protein. (280 aa)
VTI1AVesicle transport through interaction with t-SNAREs 1A. (217 aa)
ATP6AP1ATPase H+ transporting accessory protein 1. (458 aa)
ENSPCOP00000008533Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (178 aa)
TRARG1Trafficking regulator of GLUT4 (SLC2A4) 1. (177 aa)
STX6Syntaxin 6; Belongs to the syntaxin family. (255 aa)
STAM2Signal transducing adaptor molecule 2. (525 aa)
SORT1Sortilin. (831 aa)
GRIP2Glutamate receptor interacting protein 2. (961 aa)
ENSPCOP00000009180Uncharacterized protein. (265 aa)
SNX12Sorting nexin 12. (171 aa)
TBC1D17TBC1 domain family member 17. (648 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa)
RAB17RAB17, member RAS oncogene family. (210 aa)
VTI1BVesicle transport through interaction with t-SNAREs 1B. (232 aa)
YKT6YKT6 v-SNARE homolog; Belongs to the synaptobrevin family. (198 aa)
TMEM87BTransmembrane protein 87B. (520 aa)
DCLK1Doublecortin like kinase 1; Belongs to the protein kinase superfamily. (399 aa)
LOC105821613Rab-GAP TBC domain-containing protein. (531 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (796 aa)
CMTM6CKLF like MARVEL transmembrane domain containing 6. (183 aa)
CHMP2ACharged multivesicular body protein 2A. (231 aa)
PHETA1PH domain containing endocytic trafficking adaptor 1. (160 aa)
MVB12AMultivesicular body subunit 12A. (289 aa)
VTA1Vesicle trafficking 1. (281 aa)
RAB14RAB14, member RAS oncogene family. (215 aa)
ENSPCOP00000012420CNH domain-containing protein. (70 aa)
ENSPCOP00000012421WASH-7_N domain-containing protein. (173 aa)
MVB12BMultivesicular body subunit 12B. (317 aa)
TRIM27Tripartite motif containing 27. (513 aa)
ENTR1Endosome associated trafficking regulator 1. (435 aa)
VPS26AUncharacterized protein. (327 aa)
AP5B1Adaptor related protein complex 5 subunit beta 1. (877 aa)
VPS29Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (213 aa)
LOC105821645CAP-ZIP_m domain-containing protein. (1274 aa)
LAPTM4ALysosomal protein transmembrane 4 alpha. (233 aa)
ENSPCOP00000014900PX domain-containing protein. (371 aa)
LAMTOR1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa)
CHMP4BCharged multivesicular body protein 4B. (224 aa)
RAB7BRAB7B, member RAS oncogene family. (199 aa)
CALYCalcyon neuron specific vesicular protein. (213 aa)
VPS25Vacuolar protein sorting 25 homolog. (176 aa)
NSG2Neuronal vesicle trafficking associated 2. (171 aa)
LYSTLysosomal trafficking regulator. (3630 aa)
ENSPCOP00000016411Uncharacterized protein. (44 aa)
DENND5ADENN domain containing 5A. (1288 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1426 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
GRIPAP1GRIP1 associated protein 1. (841 aa)
ARHGAP1Rho GTPase activating protein 1. (444 aa)
CRACR2ACalcium release activated channel regulator 2A. (729 aa)
SNX30Sorting nexin family member 30. (408 aa)
DPY30Dpy-30 histone methyltransferase complex regulatory subunit. (99 aa)
TBC1D5TBC1 domain family member 5. (767 aa)
SNX32Sorting nexin; Involved in several stages of intracellular trafficking. (403 aa)
ERC1ELKS/RAB6-interacting/CAST family member 1. (737 aa)
GRIP1Glutamate receptor interacting protein 1. (1104 aa)
AP5M1Adaptor related protein complex 5 subunit mu 1; Belongs to the adaptor complexes medium subunit family. (486 aa)
ITSN1Intersectin 1. (1697 aa)
ANKRD50Ankyrin repeat domain 50. (1429 aa)
BAIAP3BAI1 associated protein 3. (1016 aa)
VPS54VPS54 subunit of GARP complex. (976 aa)
DCTN1CAP-Gly domain-containing protein. (1290 aa)
TMEM87ATransmembrane protein 87A. (508 aa)
CHMP4CCharged multivesicular body protein 4C. (135 aa)
MICALL2MICAL like 2. (890 aa)
TBC1D10CTBC1 domain family member 10C. (446 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2053 aa)
TBC1D10BTBC1 domain family member 10B. (825 aa)
TSG101Tumor susceptibility 101. (391 aa)
MICALL1MICAL like 1. (860 aa)
VPS36Vacuolar protein sorting 36 homolog. (386 aa)
SNX2Sorting nexin 2. (492 aa)
TINAGL1Tubulointerstitial nephritis antigen like 1; Belongs to the peptidase C1 family. (467 aa)
ENSPCOP00000020579Uncharacterized protein. (737 aa)
LOC105821266Sorting nexin; Involved in several stages of intracellular trafficking. (399 aa)
SNX18Sorting nexin. (622 aa)
SCRIBScribble planar cell polarity protein. (1598 aa)
TBC1D14Rab-GAP TBC domain-containing protein. (305 aa)
LOC105823974WH2 domain-containing protein. (464 aa)
HEATR5AHEAT repeat containing 5A. (1955 aa)
AGAP2ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1193 aa)
KIAA1109KIAA1109. (4703 aa)
SNX1Sorting nexin 1. (521 aa)
ITSN2Intersectin 2. (1679 aa)
SRLSarcalumenin; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (473 aa)
UBE2OUbiquitin conjugating enzyme E2 O. (1293 aa)
ZFYVE16Zinc finger FYVE-type containing 16. (1544 aa)
SNX4Sorting nexin 4. (420 aa)
ENSPCOP00000022489Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (185 aa)
CCDC22Coiled-coil domain containing 22. (627 aa)
VPS50VPS50 subunit of EARP/GARPII complex. (899 aa)
ACAP2ArfGAP with coiled-coil, ankyrin repeat and PH domains 2. (777 aa)
SNX33Sorting nexin. (574 aa)
SPAG9Sperm associated antigen 9. (1323 aa)
EHD4EH domain containing 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (541 aa)
ENSPCOP00000023416Uncharacterized protein. (1196 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (525 aa)
SNX27Sorting nexin 27. (529 aa)
AP3D1Adaptor related protein complex 3 subunit delta 1. (1208 aa)
ARFRP1ADP ribosylation factor related protein 1. (201 aa)
LAPTM4BLysosomal protein transmembrane 4 beta. (314 aa)
TMEM50BTransmembrane protein 50B. (158 aa)
PREPLProlyl endopeptidase like. (727 aa)
STX16Syntaxin 16; Belongs to the syntaxin family. (326 aa)
STX5Syntaxin 5; Belongs to the syntaxin family. (355 aa)
VPS28Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (221 aa)
LMTK2Lemur tyrosine kinase 2. (1466 aa)
GCC2GRIP and coiled-coil domain containing 2. (1688 aa)
ENSPCOP00000025823Uncharacterized protein. (583 aa)
DENND1ADENN domain containing 1A. (1009 aa)
DENND1BDENN domain containing 1B. (767 aa)
PLEKHJ1PH domain-containing protein. (149 aa)
ANKFY1Ankyrin repeat and FYVE domain containing 1. (1210 aa)
ALS2Alsin Rho guanine nucleotide exchange factor ALS2. (1475 aa)
RAB35RAB35, member RAS oncogene family. (201 aa)
SGSM2Small G protein signaling modulator 2. (1052 aa)
EPG5Ectopic P-granules autophagy protein 5 homolog. (2493 aa)
RAB10RAB10, member RAS oncogene family. (200 aa)
GGA1Golgi associated, gamma adaptin ear containing, ARF binding protein 1. (646 aa)
SNF8Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
LEPROTLeptin receptor overlapping transcript. (131 aa)
RAB29RAB29, member RAS oncogene family. (204 aa)
GBF1Golgi brefeldin A resistant guanine nucleotide exchange factor 1. (1861 aa)
VPS26CVPS26 endosomal protein sorting factor C. (297 aa)
RAB11FIP4RAB11 family interacting protein 4. (637 aa)
STX10Syntaxin 10. (248 aa)
UBXN6UBX domain protein 6. (442 aa)
LRRC1Leucine rich repeat containing 1. (484 aa)
VPS51VPS51 subunit of GARP complex. (791 aa)
SNX9Sorting nexin. (591 aa)
LOC105825493Annexin. (337 aa)
VPS52VPS52 subunit of GARP complex. (723 aa)
VPS16Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (841 aa)
RILPRab interacting lysosomal protein. (403 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1424 aa)
ARL4CADP ribosylation factor like GTPase 4C; Belongs to the small GTPase superfamily. Arf family. (204 aa)
VPS53VPS53 subunit of GARP complex. (832 aa)
HEATR5BHEAT repeat containing 5B. (1706 aa)
VPS26BVPS26, retromer complex component B. (336 aa)
PTPN23Protein tyrosine phosphatase non-receptor type 23. (1629 aa)
GGA3Golgi associated, gamma adaptin ear containing, ARF binding protein 3. (722 aa)
WASWASP actin nucleation promoting factor. (503 aa)
EPS15L1Epidermal growth factor receptor pathway substrate 15 like 1. (910 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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