STRINGSTRING
TMEM114 TMEM114 CXADR CXADR FZD6 FZD6 NEDD4 NEDD4 CRB2 CRB2 MPDZ MPDZ CTNNB1 CTNNB1 TJP1 TJP1 CDH2 CDH2 OCLN OCLN MTCL1 MTCL1 PALM PALM CLDN7 CLDN7 KRT19 KRT19 JUP JUP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TMEM114Transmembrane protein 114. (223 aa)
CXADRUncharacterized protein. (352 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa)
NEDD4NEDD4 E3 ubiquitin protein ligase. (1320 aa)
CRB2Crumbs cell polarity complex component 2. (1230 aa)
MPDZMultiple PDZ domain crumbs cell polarity complex component. (2083 aa)
CTNNB1Catenin beta 1. (781 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1768 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (516 aa)
MTCL1Microtubule crosslinking factor 1. (1897 aa)
PALMParalemmin. (376 aa)
CLDN7Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
KRT19Keratin 19; Belongs to the intermediate filament family. (406 aa)
JUPJunction plakoglobin. (745 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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