STRINGSTRING
TOE1 TOE1 SNRPB2 SNRPB2 ENSPCOP00000001194 ENSPCOP00000001194 LOC105820095 LOC105820095 SNRPC SNRPC CELF3 CELF3 HEXIM2 HEXIM2 SNRNP35 SNRNP35 SNRPD3 SNRPD3 PRPF4 PRPF4 SART3 SART3 LSM4-2 LSM4-2 GEMIN5 GEMIN5 RBM41 RBM41 LSM3-2 LSM3-2 PRPF8 PRPF8 LOC105817177 LOC105817177 ISG20 ISG20 RO60 RO60 LSM3 LSM3 LSM7 LSM7 TUT1 TUT1 LSM11 LSM11 DDX39B DDX39B HNRNPU HNRNPU DDX21 DDX21 LSM4 LSM4 RBM22 RBM22 LSM2 LSM2 PRPF31 PRPF31 MEPCE MEPCE ENSPCOP00000018667 ENSPCOP00000018667 SNRPC-2 SNRPC-2 LRMDA LRMDA ENSPCOP00000021398 ENSPCOP00000021398 SNRNP70 SNRNP70 SNRPA1 SNRPA1 LARP7 LARP7 CDK9 CDK9 CCNT2 CCNT2 CCNT1 CCNT1 SNU13 SNU13 SNRPA SNRPA METTL16 METTL16
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TOE1Target of EGR1, exonuclease. (507 aa)
SNRPB2Small nuclear ribonucleoprotein polypeptide B2. (225 aa)
ENSPCOP00000001194Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa)
LOC105820095Uncharacterized protein. (784 aa)
SNRPCU1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (178 aa)
CELF3CUGBP Elav-like family member 3. (464 aa)
HEXIM2HEXIM P-TEFb complex subunit 2. (286 aa)
SNRNP35Small nuclear ribonucleoprotein U11/U12 subunit 35. (247 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
PRPF4Pre-mRNA processing factor 4. (543 aa)
SART3Spliceosome associated factor 3, U4/U6 recycling protein. (902 aa)
LSM4-2U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (115 aa)
GEMIN5Gem nuclear organelle associated protein 5. (1461 aa)
RBM41RNA binding motif protein 41. (413 aa)
LSM3-2U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (85 aa)
PRPF8Pre-mRNA processing factor 8. (2335 aa)
LOC105817177TROVE domain-containing protein. (256 aa)
ISG20Interferon stimulated exonuclease gene 20. (174 aa)
RO60Ro60, Y RNA binding protein. (538 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
LSM7LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (103 aa)
TUT1RRM domain-containing protein. (912 aa)
LSM11LSM11, U7 small nuclear RNA associated. (352 aa)
DDX39BDExD-box helicase 39B. (428 aa)
HNRNPUUncharacterized protein. (824 aa)
DDX21DExD-box helicase 21. (758 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (139 aa)
RBM22RNA binding motif protein 22. (365 aa)
LSM2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
PRPF31Pre-mRNA processing factor 31. (517 aa)
MEPCEMethylphosphate capping enzyme. (686 aa)
ENSPCOP00000018667RRM_3 domain-containing protein. (103 aa)
SNRPC-2U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (186 aa)
LRMDALeucine rich melanocyte differentiation associated. (215 aa)
ENSPCOP00000021398RRM domain-containing protein. (83 aa)
SNRNP70Small nuclear ribonucleoprotein U1 subunit 70. (435 aa)
SNRPA1Small nuclear ribonucleoprotein polypeptide A. (255 aa)
LARP7Uncharacterized protein. (515 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (733 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (724 aa)
SNU13Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (132 aa)
SNRPASmall nuclear ribonucleoprotein polypeptide A. (287 aa)
METTL16U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] (563 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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