STRINGSTRING
NKX2-2 NKX2-2 SCYL3 SCYL3 SLIT1 SLIT1 PTPRS PTPRS LHX5 LHX5 TBX20 TBX20 ZPR1 ZPR1 MPST MPST SOX11 SOX11 ENSPCOP00000030256 ENSPCOP00000030256 ABT1 ABT1 PAX6 PAX6 BAG3 BAG3 SMO SMO ENSPCOP00000028080 ENSPCOP00000028080 VLDLR VLDLR OLIG2 OLIG2 NF1 NF1 VSTM5 VSTM5 ENSPCOP00000025710 ENSPCOP00000025710 CLN8 CLN8 WNT3A WNT3A HOXB8 HOXB8 LRP8 LRP8 RELN RELN UNCX UNCX PBX3 PBX3 GDF11 GDF11 GSX2 GSX2 HOXD10 HOXD10 GBX1 GBX1 PTCH1 PTCH1 MED12 MED12 GDNF GDNF IFT172 IFT172 EED EED DCTN1 DCTN1 LMO4 LMO4 GDF7 GDF7 LHX1 LHX1 ENSPCOP00000018033 ENSPCOP00000018033 SOX13 SOX13 ADARB1 ADARB1 PTBP2 PTBP2 LHX3 LHX3 ACTL6B ACTL6B PLXDC2 PLXDC2 FOXN4 FOXN4 DBX1 DBX1 VIT VIT LBX1 LBX1 PKD2 PKD2 PROX1 PROX1 TULP3 TULP3 MNX1 MNX1 ISL1 ISL1 GSX1 GSX1 SCYL1 SCYL1 DAAM2 DAAM2 ZIC1 ZIC1 DRAXIN DRAXIN HOXC10 HOXC10 TCTN1 TCTN1 ERCC2 ERCC2 INTU INTU ZC4H2 ZC4H2 SUFU SUFU PLXDC1 PLXDC1 GLI2 GLI2 WNT1 WNT1 PHGDH PHGDH ISL2 ISL2 DRGX DRGX RFX4 RFX4 LOC105817239 LOC105817239 CHRD CHRD PHOX2A PHOX2A SOX12 SOX12 NOTCH1 NOTCH1 DLL1 DLL1 DLL4 DLL4 PKD1 PKD1 LOXL3 LOXL3 SOX6 SOX6 DMRT3 DMRT3 LHX4 LHX4 FOXB1 FOXB1 GATA2 GATA2 LOC105812780 LOC105812780 OLIG3 OLIG3 MDGA1 MDGA1 NOG NOG SOX4 SOX4 GLI3 GLI3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NKX2-2NK2 homeobox 2. (273 aa)
SCYL3SCY1 like pseudokinase 3. (731 aa)
SLIT1Slit guidance ligand 1. (1510 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1879 aa)
LHX5LIM homeobox 5. (402 aa)
TBX20T-box transcription factor 20. (447 aa)
ZPR1Uncharacterized protein. (459 aa)
MPSTMercaptopyruvate sulfurtransferase. (333 aa)
SOX11Transcription factor SOX. (442 aa)
ENSPCOP00000030256DHC_N1 domain-containing protein. (571 aa)
ABT1Activator of basal transcription 1. (275 aa)
PAX6Paired box 6. (453 aa)
BAG3BCL2 associated athanogene 3. (577 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (789 aa)
ENSPCOP00000028080Uncharacterized protein. (597 aa)
VLDLRVery low density lipoprotein receptor. (879 aa)
OLIG2Oligodendrocyte transcription factor 2. (320 aa)
NF1Neurofibromin 1. (2841 aa)
VSTM5V-set and transmembrane domain containing 5. (200 aa)
ENSPCOP00000025710AAA_9 domain-containing protein. (83 aa)
CLN8CLN8 transmembrane ER and ERGIC protein. (288 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
HOXB8Homeobox B8. (243 aa)
LRP8LDL receptor related protein 8. (956 aa)
RELNReelin. (3445 aa)
UNCXUNC homeobox. (533 aa)
PBX3PBX homeobox 3. (434 aa)
GDF11Growth differentiation factor 11. (404 aa)
GSX2GS homeobox 2. (305 aa)
HOXD10Homeobox D10. (340 aa)
GBX1Gastrulation brain homeobox 1. (359 aa)
PTCH1Patched 1. (1449 aa)
MED12Mediator complex subunit 12. (2187 aa)
GDNFGlial cell derived neurotrophic factor. (228 aa)
IFT172Intraflagellar transport 172. (1723 aa)
EEDEmbryonic ectoderm development. (466 aa)
DCTN1CAP-Gly domain-containing protein. (1290 aa)
LMO4LIM domain only 4. (165 aa)
GDF7Growth differentiation factor 7. (447 aa)
LHX1LIM homeobox 1. (406 aa)
ENSPCOP00000018033HH_signal domain-containing protein. (110 aa)
SOX13SRY-box transcription factor 13. (615 aa)
ADARB1Adenosine deaminase RNA specific B1. (725 aa)
PTBP2Polypyrimidine tract binding protein 2. (537 aa)
LHX3Uncharacterized protein. (458 aa)
ACTL6BActin like 6B; Belongs to the actin family. (426 aa)
PLXDC2Plexin domain containing 2. (362 aa)
FOXN4Forkhead box N4. (517 aa)
DBX1Developing brain homeobox 1. (344 aa)
VITVitrin. (693 aa)
LBX1Ladybird homeobox 1. (281 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (963 aa)
PROX1Prospero homeobox 1. (737 aa)
TULP3Tubby-like protein; Belongs to the TUB family. (461 aa)
MNX1Motor neuron and pancreas homeobox 1. (347 aa)
ISL1ISL LIM homeobox 1. (349 aa)
GSX1GS homeobox 1. (259 aa)
SCYL1SCY1 like pseudokinase 1. (805 aa)
DAAM2Dishevelled associated activator of morphogenesis 2. (1077 aa)
ZIC1Zic family member 1. (447 aa)
DRAXINDraxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (349 aa)
HOXC10Homeobox C10. (342 aa)
TCTN1Tectonic family member 1. (587 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (681 aa)
INTUInturned planar cell polarity protein. (942 aa)
ZC4H2Zinc finger C4H2-type containing. (224 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (485 aa)
PLXDC1Plexin domain containing 1. (501 aa)
GLI2GLI family zinc finger 2. (1590 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
PHGDHD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)
ISL2ISL LIM homeobox 2. (359 aa)
DRGXDorsal root ganglia homeobox. (263 aa)
RFX4Regulatory factor X4. (745 aa)
LOC105817239LIM zinc-binding domain-containing protein. (89 aa)
CHRDChordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. (951 aa)
PHOX2APaired like homeobox 2A. (284 aa)
SOX12Transcription factor SOX. (314 aa)
NOTCH1Notch receptor 1. (2420 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4265 aa)
LOXL3Lysyl oxidase like 3. (753 aa)
SOX6SRY-box transcription factor 6. (828 aa)
DMRT3Doublesex and mab-3 related transcription factor 3. (474 aa)
LHX4LIM homeobox 4. (390 aa)
FOXB1Forkhead box B1. (325 aa)
GATA2GATA binding protein 2. (445 aa)
LOC105812780Uncharacterized protein. (433 aa)
OLIG3Oligodendrocyte transcription factor 3. (272 aa)
MDGA1MAM domain containing glycosylphosphatidylinositol anchor 1. (958 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
SOX4Transcription factor SOX. (479 aa)
GLI3GLI family zinc finger 3. (1580 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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