STRINGSTRING
UBQLN2 UBQLN2 GATA2 GATA2 LOC105822640 LOC105822640 PRKD1 PRKD1 NLGN1 NLGN1 GPC3 GPC3 ENSPCOP00000002927 ENSPCOP00000002927 GSG1 GSG1 CLU CLU DGKQ DGKQ PPT1 PPT1 ANKRD13A ANKRD13A SNAP91 SNAP91 VAMP4 VAMP4 CAV3 CAV3 DLL1 DLL1 HPCA HPCA PACSIN1 PACSIN1 FLOT1 FLOT1 PPP3CA PPP3CA DGKD DGKD ANKRD13B ANKRD13B NEU3 NEU3 RSPO1 RSPO1 CLIP3 CLIP3 HPCAL1 HPCAL1 LOC105806750 LOC105806750 ALOX15 ALOX15 SH3GL3 SH3GL3 SELE SELE WNT5A WNT5A ROCK1 ROCK1 HIP1R HIP1R STAP1 STAP1 LGALS3 LGALS3 NRG1 NRG1 PTPN1 PTPN1 LRRTM2 LRRTM2 APPL1 APPL1 SNX12 SNX12 SYK SYK RAB17 RAB17 APOE APOE AAK1 AAK1 APPL2 APPL2 CLN3 CLN3 CD36 CD36 SPHK1 SPHK1 ITGAV ITGAV SERPINE1 SERPINE1 SYT11 SYT11 BMP2K BMP2K SMAP1 SMAP1 BIN1 BIN1 CBL CBL PLCG2 PLCG2 CD2AP CD2AP TREM2 TREM2 BICD1 BICD1 APELA APELA C3 C3 ANO6 ANO6 ENSPCOP00000013017 ENSPCOP00000013017 PPP3CC PPP3CC ADIPOQ ADIPOQ LRSAM1 LRSAM1 STON1 STON1 ENSPCOP00000014002 ENSPCOP00000014002 NECAB2 NECAB2 EGF EGF HFE HFE NUMB NUMB CALY CALY USH1G USH1G ANXA2 ANXA2 PCSK9 PCSK9 TSC2 TSC2 PIK3CB PIK3CB DLG4 DLG4 TOR1A TOR1A PROM2 PROM2 PACSIN3 PACSIN3 TBC1D5 TBC1D5 RUFY2 RUFY2 CD300A CD300A SFRP4 SFRP4 SCYL2 SCYL2 ENSPCOP00000017794 ENSPCOP00000017794 CD63 CD63 RAB21 RAB21 ARRB1 ARRB1 ABL2 ABL2 MIB1 MIB1 SRC SRC DNAJC6 DNAJC6 ABCA2 ABCA2 BTBD9 BTBD9 NCKAP1L NCKAP1L SYT4 SYT4 LDLRAP1 LDLRAP1 STON2 STON2 ATXN2 ATXN2 TSG101 TSG101 LOC105810918 LOC105810918 DKK1 DKK1 PPP3R1 PPP3R1 SCAMP5 SCAMP5 OPHN1 OPHN1 SCRIB SCRIB DAB2 DAB2 RAB31 RAB31 RIT2 RIT2 ANKRD13D ANKRD13D LOC105826870 LOC105826870 UNC119 UNC119 CD14 CD14 ANGPT1 ANGPT1 LRPAP1 LRPAP1 APOA5 APOA5 NTF3 NTF3 ZFYVE16 ZFYVE16 CDC42 CDC42 B2M B2M SNX33 SNX33 EEF2K EEF2K EPHA3 EPHA3 EHD4 EHD4 NR1H3 NR1H3 TNK2 TNK2 AXL AXL ENSPCOP00000023753 ENSPCOP00000023753 CCL19 CCL19 DTNBP1 DTNBP1 TFR2 TFR2 SMPD1 SMPD1 EFNB2 EFNB2 ARF6 ARF6 RIN3 RIN3 APLN APLN RUFY1 RUFY1 ENSPCOP00000001335 ENSPCOP00000001335 CD177 CD177 ENSPCOP00000030580 ENSPCOP00000030580 WDR54 WDR54 RAB4B RAB4B ATAD1 ATAD1 FMR1 FMR1 VEGFA VEGFA RUBCN RUBCN CD22 CD22 RABGEF1 RABGEF1 WASL WASL LRRK2 LRRK2 CAV1 CAV1 ARRB2 ARRB2 PACSIN2 PACSIN2 SYNJ1 SYNJ1 PPP3CB PPP3CB WNT3A WNT3A VPS28 VPS28 INSR INSR DNM2 DNM2 TF TF LRRTM1 LRRTM1 ANKFY1 ANKFY1 ITGA2 ITGA2 DRD4 DRD4 SDCBP SDCBP APOC2 APOC2 LOC105822688 LOC105822688 CLUL1 CLUL1 ABCA7 ABCA7 PICALM PICALM ARF1 ARF1 SYNJ2BP SYNJ2BP NR1H2 NR1H2 SLC17A7 SLC17A7 LOC105815192 LOC105815192 SGIP1 SGIP1 ARFGAP1 ARFGAP1 HIP1 HIP1 STX1B STX1B PICK1 PICK1 RAB4A RAB4A MAGI2 MAGI2 MCTP1 MCTP1 LRRC1 LRRC1 ENSPCOP00000030477 ENSPCOP00000030477
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UBQLN2Ubiquilin 2. (624 aa)
GATA2GATA binding protein 2. (445 aa)
LOC105822640Integrin beta; Belongs to the integrin beta chain family. (454 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (860 aa)
NLGN1Neuroligin 1. (823 aa)
GPC3Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa)
ENSPCOP00000002927Uncharacterized protein. (160 aa)
GSG1Germ cell associated 1. (341 aa)
CLUClusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (450 aa)
DGKQDiacylglycerol kinase. (939 aa)
PPT1Palmitoyl-protein thioesterase 1. (302 aa)
ANKRD13AAnkyrin repeat domain 13A. (590 aa)
SNAP91Synaptosome associated protein 91. (858 aa)
VAMP4Vesicle associated membrane protein 4. (141 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
HPCAHippocalcin. (193 aa)
PACSIN1Protein kinase C and casein kinase substrate in neurons 1. (444 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
DGKDDiacylglycerol kinase. (1171 aa)
ANKRD13BAnkyrin repeat domain 13B. (626 aa)
NEU3Neuraminidase 3. (462 aa)
RSPO1R-spondin 1. (266 aa)
CLIP3CAP-Gly domain containing linker protein 3. (548 aa)
HPCAL1Hippocalcin like 1. (199 aa)
LOC105806750Uncharacterized protein. (261 aa)
ALOX15Arachidonate 15-lipoxygenase. (663 aa)
SH3GL3SH3 domain containing GRB2 like 3, endophilin A3. (358 aa)
SELESelectin E. (610 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1316 aa)
HIP1RHuntingtin interacting protein 1 related. (1035 aa)
STAP1Signal transducing adaptor family member 1. (227 aa)
LGALS3Galectin. (250 aa)
NRG1Neuregulin 1. (710 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (435 aa)
LRRTM2Leucine rich repeat transmembrane neuronal 2. (516 aa)
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (661 aa)
SNX12Sorting nexin 12. (171 aa)
SYKSpleen associated tyrosine kinase. (637 aa)
RAB17RAB17, member RAS oncogene family. (210 aa)
APOEApolipoprotein E. (314 aa)
AAK1AP2 associated kinase 1. (963 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (591 aa)
CLN3Battenin. (438 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
SPHK1Sphingosine kinase 1. (469 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1047 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (402 aa)
SYT11Synaptotagmin 11. (431 aa)
BMP2KProtein kinase domain-containing protein. (616 aa)
SMAP1Small ArfGAP 1. (300 aa)
BIN1Bridging integrator 1. (594 aa)
CBLCbl proto-oncogene. (891 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1233 aa)
CD2APCD2 associated protein. (534 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (224 aa)
BICD1BICD cargo adaptor 1. (979 aa)
APELAApelin receptor early endogenous ligand. (54 aa)
C3Complement C3. (1551 aa)
ANO6Anoctamin. (932 aa)
ENSPCOP00000013017Uncharacterized protein. (47 aa)
PPP3CCSerine/threonine-protein phosphatase. (520 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
LRSAM1Leucine rich repeat and sterile alpha motif containing 1. (674 aa)
STON1Stonin-1; May be involved in the endocytic machinery. (730 aa)
ENSPCOP00000014002Uncharacterized protein. (286 aa)
NECAB2N-terminal EF-hand calcium binding protein 2. (319 aa)
EGFEpidermal growth factor. (1132 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (348 aa)
NUMBNUMB endocytic adaptor protein. (628 aa)
CALYCalcyon neuron specific vesicular protein. (213 aa)
USH1GUSH1 protein network component sans. (461 aa)
ANXA2Annexin. (339 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9. (693 aa)
TSC2TSC complex subunit 2. (1814 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
DLG4Uncharacterized protein; Belongs to the MAGUK family. (602 aa)
TOR1ATorsin. (332 aa)
PROM2Prominin 2. (834 aa)
PACSIN3Protein kinase C and casein kinase substrate in neurons 3. (424 aa)
TBC1D5TBC1 domain family member 5. (767 aa)
RUFY2RUN and FYVE domain containing 2. (527 aa)
CD300ACD300a molecule. (299 aa)
SFRP4Secreted frizzled related protein 4. (342 aa)
SCYL2SCY1 like pseudokinase 2. (933 aa)
ENSPCOP00000017794Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (84 aa)
CD63Tetraspanin. (237 aa)
RAB21RAB21, member RAS oncogene family. (204 aa)
ARRB1Arrestin beta 1. (429 aa)
ABL2Tyrosine-protein kinase. (1154 aa)
MIB1Mindbomb E3 ubiquitin protein ligase 1. (829 aa)
SRCTyrosine-protein kinase. (543 aa)
DNAJC6DnaJ heat shock protein family (Hsp40) member C6. (971 aa)
ABCA2ATP binding cassette subfamily A member 2. (2452 aa)
BTBD9BTB domain containing 9. (611 aa)
NCKAP1LNCK associated protein 1 like. (1138 aa)
SYT4Synaptotagmin 4. (423 aa)
LDLRAP1Low density lipoprotein receptor adaptor protein 1. (308 aa)
STON2Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating; Belongs to the Stoned B family. (771 aa)
ATXN2Ataxin 2. (1275 aa)
TSG101Tumor susceptibility 101. (391 aa)
LOC105810918Uncharacterized protein. (129 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (268 aa)
PPP3R1Uncharacterized protein. (189 aa)
SCAMP5Secretory carrier-associated membrane protein. (235 aa)
OPHN1Oligophrenin 1. (683 aa)
SCRIBScribble planar cell polarity protein. (1598 aa)
DAB2DAB adaptor protein 2. (769 aa)
RAB31RAB31, member RAS oncogene family. (195 aa)
RIT2Ras like without CAAX 2. (164 aa)
ANKRD13DAnkyrin repeat domain 13D. (605 aa)
LOC105826870Uncharacterized protein. (244 aa)
UNC119Unc-119 lipid binding chaperone. (240 aa)
CD14Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (375 aa)
ANGPT1Angiopoietin 1. (408 aa)
LRPAP1LDL receptor related protein associated protein 1. (359 aa)
APOA5Apolipoprotein A5. (371 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (270 aa)
ZFYVE16Zinc finger FYVE-type containing 16. (1544 aa)
CDC42Uncharacterized protein. (191 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (120 aa)
SNX33Sorting nexin. (574 aa)
EEF2KEukaryotic elongation factor 2 kinase. (725 aa)
EPHA3EPH receptor A3. (831 aa)
EHD4EH domain containing 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (541 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (454 aa)
TNK2Tyrosine kinase non receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1088 aa)
AXLAXL receptor tyrosine kinase. (894 aa)
ENSPCOP00000023753Stonin2_N domain-containing protein. (164 aa)
CCL19C-C motif chemokine. (108 aa)
DTNBP1Dystrobrevin binding protein 1. (352 aa)
TFR2Transferrin receptor 2. (806 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (627 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (335 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
RIN3Ras and Rab interactor 3. (981 aa)
APLNApelin. (77 aa)
RUFY1RUN and FYVE domain containing 1. (702 aa)
ENSPCOP00000001335Muskelin_N domain-containing protein. (87 aa)
CD177CD177 molecule. (439 aa)
ENSPCOP00000030580Uncharacterized protein. (126 aa)
WDR54WD repeat domain 54. (334 aa)
RAB4BUncharacterized protein. (215 aa)
ATAD1ATPase family AAA domain containing 1; Belongs to the AAA ATPase family. (383 aa)
FMR1Fragile X mental retardation 1. (611 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa)
RUBCNRubicon autophagy regulator. (963 aa)
CD22CD22 molecule. (838 aa)
RABGEF1Uncharacterized protein. (501 aa)
WASLWASP like actin nucleation promoting factor. (505 aa)
LRRK2Leucine rich repeat kinase 2. (2427 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
ARRB2Arrestin beta 2. (441 aa)
PACSIN2Protein kinase C and casein kinase substrate in neurons 2. (486 aa)
SYNJ1Synaptojanin 1. (1460 aa)
PPP3CBSerine/threonine-protein phosphatase. (531 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
VPS28Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (221 aa)
INSRInsulin receptor. (1192 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
TFTransferrin; Belongs to the transferrin family. (697 aa)
LRRTM1Leucine rich repeat transmembrane neuronal 1. (522 aa)
ANKFY1Ankyrin repeat and FYVE domain containing 1. (1210 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1129 aa)
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (333 aa)
SDCBPUncharacterized protein. (298 aa)
APOC2Apolipoprotein C2. (101 aa)
LOC105822688Uncharacterized protein. (54 aa)
CLUL1Clusterin; Belongs to the clusterin family. (473 aa)
ABCA7ATP binding cassette subfamily A member 7. (2015 aa)
PICALMPhosphatidylinositol binding clathrin assembly protein. (652 aa)
ARF1ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
SYNJ2BPSynaptojanin 2 binding protein. (134 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (459 aa)
SLC17A7Solute carrier family 17 member 7. (573 aa)
LOC105815192Annexin. (287 aa)
SGIP1SH3 domain GRB2 like endophilin interacting protein 1. (842 aa)
ARFGAP1ADP ribosylation factor GTPase activating protein 1. (423 aa)
HIP1Huntingtin interacting protein 1. (1037 aa)
STX1BSyntaxin 1B; Belongs to the syntaxin family. (291 aa)
PICK1Protein interacting with PRKCA 1. (417 aa)
RAB4ARAB4A, member RAS oncogene family. (221 aa)
MAGI2Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1453 aa)
MCTP1Multiple C2 and transmembrane domain containing 1. (998 aa)
LRRC1Leucine rich repeat containing 1. (484 aa)
ENSPCOP00000030477PDZ domain-containing protein. (263 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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