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| | ARMC5 | Armadillo repeat containing 5. (931 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (543 aa) |
| | GLI3 | GLI family zinc finger 3. (1580 aa) |
| | SOX4 | Transcription factor SOX. (479 aa) |
| | NRARP | NOTCH regulated ankyrin repeat protein. (114 aa) |
| | IL7R | Interleukin 7 receptor. (456 aa) |
| | LOC105827009 | 40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (246 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2536 aa) |
| | TSC1 | TSC complex subunit 1. (1164 aa) |
| | NCAPH2 | Non-SMC condensin II complex subunit H2. (608 aa) |
| | SASH3 | SAM and SH3 domain containing 3. (380 aa) |
| | RORC | RAR related orphan receptor C. (520 aa) |
| | RSAD2 | Radical S-adenosyl methionine domain containing 2. (361 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (442 aa) |
| | FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa) |
| | DLL4 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa) |
| | JAG2 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1101 aa) |
| | HLX | H2.0 like homeobox. (487 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (432 aa) |
| | RELB | RELB proto-oncogene, NF-kB subunit. (552 aa) |
| | XRCC4 | X-ray repair cross complementing 4. (297 aa) |
| | CD3D | Uncharacterized protein. (97 aa) |
| | EOMES | Eomesodermin. (705 aa) |
| | ANXA1 | Annexin. (346 aa) |
| | CHD7 | Chromodomain helicase DNA binding protein 7. (2997 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) |
| | PRKDC | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4130 aa) |
| | TBX21 | T-box transcription factor 21. (535 aa) |
| | STAT6 | Signal transducer and activator of transcription. (846 aa) |
| | PRR7 | Proline rich 7, synaptic. (276 aa) |
| | CD8A | CD8a molecule. (239 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | PIK3R3 | Uncharacterized protein. (454 aa) |
| | IL6 | Uncharacterized protein. (211 aa) |
| | ZFP36L2 | ZFP36 ring finger protein like 2. (493 aa) |
| | ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa) |
| | TESPA1 | Thymocyte expressed, positive selection associated 1. (518 aa) |
| | PTPN22 | Protein tyrosine phosphatase non-receptor type 22. (653 aa) |
| | CD4 | CD4 molecule. (452 aa) |
| | GATA3 | Uncharacterized protein. (444 aa) |
| | IL7 | Interleukin 7. (133 aa) |
| | FZD8 | Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (406 aa) |
| | IRF1 | Interferon regulatory factor. (324 aa) |
| | SYK | Spleen associated tyrosine kinase. (637 aa) |
| | BCL6 | BCL6 transcription repressor. (706 aa) |
| | CD74 | CD74 molecule. (298 aa) |
| | LCK | Tyrosine-protein kinase. (417 aa) |
| | ZFPM1 | Zinc finger protein, FOG family member 1. (728 aa) |
| | TRAF3IP2 | TRAF3 interacting protein 2. (562 aa) |
| | CCR7 | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa) |
| | TOX | Thymocyte selection associated high mobility group box. (526 aa) |
| | FOXP1 | Forkhead box P1. (693 aa) |
| | LEPR | Leptin receptor. (1055 aa) |
| | CD3E | CD3e molecule. (187 aa) |
| | FOXN1 | Forkhead box N1. (648 aa) |
| | SP3 | Sp3 transcription factor. (781 aa) |
| | THEMIS | Thymocyte selection associated. (586 aa) |
| | CLEC4E | C-type lectin domain family 4 member E. (218 aa) |
| | PKNOX1 | PBX/knotted 1 homeobox 1. (436 aa) |
| | PTPN2 | Tyrosine-protein phosphatase non-receptor type. (415 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (326 aa) |
| | CD28 | CD28 molecule. (220 aa) |
| | CD83 | CD83 molecule. (206 aa) |
| | PLA2G2D | Phospholipase A(2). (132 aa) |
| | ENSPCOP00000013858 | Uncharacterized protein. (78 aa) |
| | NKX2-3 | NK2 homeobox 3. (361 aa) |
| | ENTPD7 | Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (604 aa) |
| | VAV1 | Vav guanine nucleotide exchange factor 1. (806 aa) |
| | BCL11B | BAF chromatin remodeling complex subunit BCL11B. (896 aa) |
| | LFNG | Beta-1,3-N-acetylglucosaminyltransferase. (377 aa) |
| | CLEC4G | C-type lectin domain family 4 member G. (293 aa) |
| | ENSPCOP00000015361 | Uncharacterized protein. (129 aa) |
| | CARD11 | Caspase recruitment domain family member 11. (1125 aa) |
| | SLAMF6 | SLAM family member 6. (330 aa) |
| | PATZ1 | POZ/BTB and AT hook containing zinc finger 1. (695 aa) |
| | IRF4 | Interferon regulatory factor 4. (451 aa) |
| | JMJD6 | Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (414 aa) |
| | MR1 | Major histocompatibility complex, class I-related; Belongs to the MHC class I family. (337 aa) |
| | CRACR2A | Calcium release activated channel regulator 2A. (729 aa) |
| | CTSL | Cathepsin L; Belongs to the peptidase C1 family. (333 aa) |
| | ENSPCOP00000017736 | Uncharacterized protein. (177 aa) |
| | SOX13 | SRY-box transcription factor 13. (615 aa) |
| | FOXP3 | Forkhead box P3. (433 aa) |
| | ENSPCOP00000018033 | HH_signal domain-containing protein. (110 aa) |
| | TMEM98 | Transmembrane protein 98. (226 aa) |
| | IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (135 aa) |
| | PIK3R2 | Uncharacterized protein. (726 aa) |
| | BCL3 | BCL3 transcription coactivator. (454 aa) |
| | ADA | Adenosine deaminase. (363 aa) |
| | SEMA4A | Semaphorin 4A; Belongs to the semaphorin family. (761 aa) |
| | RC3H1 | Ring finger and CCCH-type domains 1. (975 aa) |
| | ENSPCOP00000019705 | Uncharacterized protein. (583 aa) |
| | LMBR1L | Limb development membrane protein 1 like; Belongs to the LIMR family. (489 aa) |
| | SRF | Serum response factor. (508 aa) |
| | LY9 | Lymphocyte antigen 9. (642 aa) |
| | RABL3 | RAB, member of RAS oncogene family like 3. (236 aa) |
| | IL2RG | Fibronectin type-III domain-containing protein. (386 aa) |
| | BCL2 | BCL2 apoptosis regulator. (234 aa) |
| | FUT7 | Fucosyltransferase 7. (342 aa) |
| | ZFP36L1 | ZFP36 ring finger protein like 1. (338 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) |
| | PREX1 | Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1626 aa) |
| | PTGER4 | Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (490 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (205 aa) |
| | ATP7A | ATPase copper transporting alpha. (1502 aa) |
| | CLEC4D | C-type lectin domain family 4 member D. (215 aa) |
| | B2M | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (120 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | RORA | RAR related orphan receptor A. (532 aa) |
| | ENSPCOP00000023046 | Uncharacterized protein. (150 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa) |
| | DNAJA3 | DnaJ heat shock protein family (Hsp40) member A3. (429 aa) |
| | IKZF3 | IKAROS family zinc finger 3. (509 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (745 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (539 aa) |
| | TNFSF8 | TNF superfamily member 8; Belongs to the tumor necrosis factor family. (234 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (531 aa) |
| | IL21 | Interleukin 21. (110 aa) |
| | BATF | Basic leucine zipper ATF-like transcription factor. (125 aa) |
| | CCR9 | C-C motif chemokine receptor 9; Belongs to the G-protein coupled receptor 1 family. (369 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | CDK6 | Cyclin dependent kinase 6. (263 aa) |
| | AIRE | Autoimmune regulator. (544 aa) |
| | ZBTB1 | Zinc finger and BTB domain containing 1. (653 aa) |
| | ZAP70 | Tyrosine-protein kinase. (617 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1252 aa) |
| | LOC105809616 | ABA_GPCR domain-containing protein. (367 aa) |
| | NHEJ1 | Non-homologous end joining factor 1. (299 aa) |
| | IL6R | Interleukin 6 receptor. (469 aa) |
| | PAX1 | Paired box 1. (515 aa) |
| | TCIRG1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa) |
| | ADAM17 | ADAM metallopeptidase domain 17. (757 aa) |
| | STAT3 | Signal transducer and activator of transcription. (796 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | IL18R1 | Interleukin 18 receptor 1. (540 aa) |
| | RIPK3 | Receptor interacting serine/threonine kinase 3. (516 aa) |
| | TCF7 | Transcription factor 7. (303 aa) |
| | ZBTB7B | Zinc finger and BTB domain containing 7B. (572 aa) |
| | ITPKB | Kinase; Belongs to the inositol phosphokinase (IPK) family. (945 aa) |
| | IL4R | Interleukin 4 receptor. (808 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa) |
| | ITK | Tyrosine-protein kinase. (598 aa) |
| | ABL1 | Tyrosine-protein kinase. (1146 aa) |
| | RC3H2 | Ring finger and CCCH-type domains 2. (1183 aa) |
