STRINGSTRING
KREMEN1 KREMEN1 LRP4 LRP4 SRGN SRGN SFRP1 SFRP1 SOX9 SOX9 ECM1 ECM1 PTK2B PTK2B RFLNA RFLNA CALCR CALCR TGFB1 TGFB1 RFLNB RFLNB TPH1 TPH1 ENPP1 ENPP1 SOST SOST BCL2 BCL2 DKK1 DKK1 GATA1 GATA1 LTBP3 LTBP3 KREMEN2 KREMEN2 AHSG AHSG VDR VDR MDK MDK GFRA4 GFRA4 MEF2C MEF2C CHSY1 CHSY1 BCOR BCOR FGF23 FGF23 HIF1A HIF1A NOTCH1 NOTCH1 SMAD6 SMAD6 SMAD7 SMAD7 TRPM4 TRPM4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KREMEN1Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (458 aa)
LRP4LDL receptor related protein 4. (1922 aa)
SRGNSerglycin. (153 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
SOX9SRY-box transcription factor 9. (505 aa)
ECM1Extracellular matrix protein 1. (570 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (967 aa)
RFLNARefilin A. (208 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (479 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
RFLNBRefilin B. (146 aa)
TPH1Tryptophan hydroxylase 1. (444 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (925 aa)
SOSTSclerostin. (213 aa)
BCL2BCL2 apoptosis regulator. (234 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (268 aa)
GATA1GATA binding protein 1. (413 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1306 aa)
KREMEN2Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (460 aa)
AHSGAlpha 2-HS glycoprotein. (364 aa)
VDRVitamin D receptor. (474 aa)
MDKMidkine. (143 aa)
GFRA4GDNF family receptor alpha 4. (259 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
CHSY1Hexosyltransferase. (804 aa)
BCORBCL6 corepressor. (1760 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (826 aa)
NOTCH1Notch receptor 1. (2420 aa)
SMAD6Mothers against decapentaplegic homolog. (500 aa)
SMAD7Mothers against decapentaplegic homolog. (490 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1204 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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