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SLC4A10 SLC4A10 CA2 CA2 SLC9A3 SLC9A3 TMEM9 TMEM9 CLIC4 CLIC4 SLC26A6 SLC26A6 SLC12A5 SLC12A5 SLC4A8 SLC4A8 F5 F5 ATP6V0B ATP6V0B TM9SF4 TM9SF4 MAPK3 MAPK3 ATP6AP1 ATP6AP1 TMEM106B TMEM106B ATP6V1F ATP6V1F SLC4A3 SLC4A3 RAB39A RAB39A DMXL2 DMXL2 SLC4A1 SLC4A1 SLC11A1 SLC11A1 UBE3A UBE3A RAB38 RAB38 ATP6AP1L ATP6AP1L AVPR1B AVPR1B SLC9A4 SLC9A4 TMEM199 TMEM199 AVP AVP CHP1 CHP1 AQP11 AQP11 BCL2 BCL2 ATP6V0A4 ATP6V0A4 MAFG MAFG ATP6AP2 ATP6AP2 SLC9A9 SLC9A9 SLC9A7 SLC9A7 RAB20 RAB20 LRRK2 LRRK2 CA7 CA7 VPS33A VPS33A ATP6V0A2 ATP6V0A2 HVCN1 HVCN1 SLC9A2 SLC9A2 SLC4A7 SLC4A7 SNAPIN SNAPIN LOC105809616 LOC105809616 CLN6 CLN6 TMEM165 TMEM165 MAPK1 MAPK1 TCIRG1 TCIRG1 NOX1 NOX1 SLC4A9 SLC4A9 SLC9A5 SLC9A5 TMEM175 TMEM175 SLC9A1 SLC9A1 CCDC115 CCDC115 SLC9C2 SLC9C2 ATP5F1B ATP5F1B SLC4A4 SLC4A4 CLN3 CLN3 RNASEK RNASEK ATP6V0C ATP6V0C SLC4A5 SLC4A5 DMXL1 DMXL1 GRN GRN SLC26A3 SLC26A3 SLAMF8 SLAMF8 LACC1 LACC1 SLC9A6 SLC9A6 PPT1 PPT1 AVPR1A AVPR1A RAB7A RAB7A ATP6V1H ATP6V1H CFTR CFTR ATP6V1B2 ATP6V1B2 ATP1A4 ATP1A4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLC4A10Anion exchange protein. (1133 aa)
CA2Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (260 aa)
SLC9A3Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (834 aa)
TMEM9Transmembrane protein 9. (183 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa)
SLC26A6Solute carrier family 26 member 6. (757 aa)
SLC12A5Solute carrier family 12 member 5. (1134 aa)
SLC4A8Anion exchange protein. (1092 aa)
F5Coagulation factor V; Belongs to the multicopper oxidase family. (2155 aa)
ATP6V0BATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family. (291 aa)
TM9SF4Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (664 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
ATP6AP1ATPase H+ transporting accessory protein 1. (458 aa)
TMEM106BTransmembrane protein 106B. (235 aa)
ATP6V1FV-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
SLC4A3Anion exchange protein. (1233 aa)
RAB39ARAB39A, member RAS oncogene family. (217 aa)
DMXL2Dmx like 2. (2622 aa)
SLC4A1Anion exchange protein. (917 aa)
SLC11A1Solute carrier family 11 member 1. (546 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (870 aa)
RAB38RAB38, member RAS oncogene family. (211 aa)
ATP6AP1LATPase H+ transporting accessory protein 1 like. (213 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (420 aa)
SLC9A4Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (797 aa)
TMEM199Transmembrane protein 199. (211 aa)
AVPArginine vasopressin. (116 aa)
CHP1Calcineurin like EF-hand protein 1. (201 aa)
AQP11Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (271 aa)
BCL2BCL2 apoptosis regulator. (234 aa)
ATP6V0A4V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (840 aa)
MAFGMAF bZIP transcription factor G. (162 aa)
ATP6AP2ATPase H+ transporting accessory protein 2. (273 aa)
SLC9A9Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (559 aa)
SLC9A7Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (725 aa)
RAB20RAB20, member RAS oncogene family. (234 aa)
LRRK2Leucine rich repeat kinase 2. (2427 aa)
CA7Carbonic anhydrase 7; Belongs to the alpha-carbonic anhydrase family. (264 aa)
VPS33AUncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (506 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (829 aa)
HVCN1Hydrogen voltage gated channel 1. (271 aa)
SLC9A2Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (812 aa)
SLC4A7Anion exchange protein. (1206 aa)
SNAPINSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
LOC105809616ABA_GPCR domain-containing protein. (367 aa)
CLN6CLN6 transmembrane ER protein. (296 aa)
TMEM165GDT1 family protein. (322 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
NOX1NADPH oxidase 1. (564 aa)
SLC4A9Anion exchange protein. (974 aa)
SLC9A5Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (896 aa)
TMEM175Transmembrane protein 175. (503 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
CCDC115Coiled-coil domain containing 115. (177 aa)
SLC9C2Solute carrier family 9 member C2 (putative). (1045 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (529 aa)
SLC4A4Anion exchange protein. (884 aa)
CLN3Battenin. (438 aa)
RNASEKRibonuclease K. (131 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (154 aa)
SLC4A5Anion exchange protein. (1132 aa)
DMXL1Dmx like 1. (3048 aa)
GRNGranulin precursor. (591 aa)
SLC26A3Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (759 aa)
SLAMF8SLAM family member 8. (268 aa)
LACC1Uncharacterized protein. (380 aa)
SLC9A6Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (701 aa)
PPT1Palmitoyl-protein thioesterase 1. (302 aa)
AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (410 aa)
RAB7ARAB7A, member RAS oncogene family. (161 aa)
ATP6V1HV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (453 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1426 aa)
ATP6V1B2ATPase H+ transporting V1 subunit B2. (448 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1031 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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