STRINGSTRING
EIF6 EIF6 UTP23 UTP23 FBL FBL PES1 PES1 LOC105817821 LOC105817821 MPHOSPH10 MPHOSPH10 NSA2 NSA2 UTP14A UTP14A RRP1 RRP1 ENSPCOP00000012298 ENSPCOP00000012298 RRP1B RRP1B NOP9 NOP9 ENSPCOP00000012921 ENSPCOP00000012921 RRP36 RRP36 RPS7 RPS7 UTP18 UTP18 NOL6 NOL6 UTP11 UTP11 ENSPCOP00000015258 ENSPCOP00000015258 NOC2L NOC2L TBL3 TBL3 FAM207A FAM207A ZNF622 ZNF622 WDR12 WDR12 WDR36 WDR36 NOC4L NOC4L BYSL BYSL FBLL1 FBLL1 WDR46 WDR46 RIOK3 RIOK3 LAS1L LAS1L EBNA1BP2 EBNA1BP2 BOP1 BOP1 ENSPCOP00000022366 ENSPCOP00000022366 PDCD11 PDCD11 BMS1 BMS1 FTSJ3 FTSJ3 RIOK2 RIOK2 MDN1 MDN1 NOP56 NOP56 NOL10 NOL10 WDR74 WDR74 UTP20 UTP20 RRP9 RRP9 UTP4 UTP4 NGDN NGDN NOP14 NOP14 EMG1 EMG1 ENSPCOP00000001176 ENSPCOP00000001176 KRI1 KRI1 ENSPCOP00000001724 ENSPCOP00000001724 ENSPCOP00000001984 ENSPCOP00000001984 RRP15 RRP15 HUNK HUNK ENSPCOP00000003048 ENSPCOP00000003048 UTP6 UTP6 ENSPCOP00000003875 ENSPCOP00000003875 ENSPCOP00000003934 ENSPCOP00000003934 IMP3 IMP3 UTP25 UTP25 KRR1 KRR1 FCF1 FCF1 XRCC5 XRCC5 PRKDC PRKDC MRTO4 MRTO4 ENSPCOP00000006309 ENSPCOP00000006309
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (291 aa)
UTP23Uncharacterized protein. (141 aa)
FBLFibrillarin. (323 aa)
PES1Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. (588 aa)
LOC105817821X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (689 aa)
MPHOSPH10U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; Belongs to the MPP10 family. (662 aa)
NSA2Uncharacterized protein. (260 aa)
UTP14AUncharacterized protein. (770 aa)
RRP1Ribosomal RNA processing 1. (449 aa)
ENSPCOP00000012298Uncharacterized protein. (118 aa)
RRP1BRibosomal RNA processing 1B. (732 aa)
NOP9NOP9 nucleolar protein. (631 aa)
ENSPCOP00000012921Ribosomal_L28e domain-containing protein. (150 aa)
RRP36Ribosomal RNA processing 36. (250 aa)
RPS740S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa)
UTP18UTP18 small subunit processome component. (556 aa)
NOL6Nucleolar protein 6. (1146 aa)
UTP11U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA. (253 aa)
ENSPCOP00000015258Peptidyl-prolyl cis-trans isomerase. (108 aa)
NOC2LNOC2 like nucleolar associated transcriptional repressor. (744 aa)
TBL3Transducin beta like 3. (808 aa)
FAM207AFamily with sequence similarity 207 member A. (218 aa)
ZNF622Zinc finger protein 622. (473 aa)
WDR12Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (398 aa)
WDR36WD repeat domain 36. (820 aa)
NOC4LNucleolar complex associated 4 homolog. (516 aa)
BYSLUncharacterized protein. (437 aa)
FBLL1Fibrillarin like 1. (303 aa)
WDR46WD repeat domain 46. (612 aa)
RIOK3Serine/threonine-protein kinase RIO3; Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. (519 aa)
LAS1LLAS1 like, ribosome biogenesis factor. (721 aa)
EBNA1BP2EBNA1 binding protein 2. (334 aa)
BOP1Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (737 aa)
ENSPCOP00000022366DUF663 domain-containing protein. (140 aa)
PDCD11Programmed cell death 11. (1558 aa)
BMS1Bms1-type G domain-containing protein. (1196 aa)
FTSJ3pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (838 aa)
RIOK2RIO kinase 2. (552 aa)
MDN1Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (5519 aa)
NOP56NOP56 ribonucleoprotein. (599 aa)
NOL10Nucleolar protein 10. (631 aa)
WDR74WD repeat domain 74. (384 aa)
UTP20UTP20 small subunit processome component. (2664 aa)
RRP9Ribosomal RNA processing 9, U3 small nucleolar RNA binding protein. (476 aa)
UTP4UTP4 small subunit processome component. (686 aa)
NGDNNeuroguidin. (316 aa)
NOP14NOP14 nucleolar protein. (853 aa)
EMG1EMG1 N1-specific pseudouridine methyltransferase. (244 aa)
ENSPCOP00000001176Uncharacterized protein. (402 aa)
KRI1KRI1 homolog. (679 aa)
ENSPCOP0000000172440S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (207 aa)
ENSPCOP00000001984Nop domain-containing protein. (284 aa)
RRP15Ribosomal RNA processing 15 homolog. (199 aa)
HUNKHormonally up-regulated Neu-associated kinase. (714 aa)
ENSPCOP00000003048Peptidyl-prolyl cis-trans isomerase. (131 aa)
UTP6UTP6 small subunit processome component. (598 aa)
ENSPCOP00000003875Uncharacterized protein. (40 aa)
ENSPCOP00000003934U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; Belongs to the MPP10 family. (530 aa)
IMP3IMP U3 small nucleolar ribonucleoprotein 3. (184 aa)
UTP25UTP25 small subunit processor component. (721 aa)
KRR1KRR1 small subunit processome component homolog. (261 aa)
FCF1FCF1 rRNA-processing protein. (198 aa)
XRCC5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (677 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4130 aa)
MRTO4Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (239 aa)
ENSPCOP00000006309Uncharacterized protein. (104 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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