STRINGSTRING
FOXJ2 FOXJ2 SPRED3 SPRED3 FGF10 FGF10 GRHL2 GRHL2 DLL1 DLL1 NOTCH1 NOTCH1 JAG1 JAG1 OVOL2 OVOL2 ENSPCOP00000005396 ENSPCOP00000005396 LOC105826862 LOC105826862 FST FST STAT1 STAT1 XDH XDH FRZB FRZB HES5 HES5 LOC105826865 LOC105826865 NODAL NODAL ID1 ID1 YAP1 YAP1 NKX6-3 NKX6-3 MMP9 MMP9 SPRED2 SPRED2 ZEB1 ZEB1 EZH2 EZH2 CTNNB1 CTNNB1 ACVRL1 ACVRL1 VEGFA VEGFA ENSPCOP00000025005 ENSPCOP00000025005 CAV1 CAV1 SIX2 SIX2 OSR1 OSR1 GDF3 GDF3 SPRY1 SPRY1 SPRY2 SPRY2 SRSF6 SRSF6 SPRED1 SPRED1 SMO SMO NOTCH4 NOTCH4 SOX9 SOX9 CCND1 CCND1 TP63 TP63
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FOXJ2Forkhead box J2. (527 aa)
SPRED3Sprouty related EVH1 domain containing 3. (429 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
GRHL2Grainyhead like transcription factor 2. (625 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
NOTCH1Notch receptor 1. (2420 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
OVOL2Ovo like zinc finger 2. (276 aa)
ENSPCOP00000005396Uncharacterized protein. (130 aa)
LOC105826862C-type lectin domain-containing protein. (175 aa)
FSTFollistatin. (344 aa)
STAT1Signal transducer and activator of transcription. (794 aa)
XDHXanthine dehydrogenase. (1313 aa)
FRZBFrizzled related protein. (325 aa)
HES5Orange domain-containing protein. (94 aa)
LOC105826865C-type lectin domain-containing protein. (175 aa)
NODALNodal growth differentiation factor. (348 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (154 aa)
YAP1Uncharacterized protein. (504 aa)
NKX6-3Homeobox domain-containing protein. (263 aa)
MMP9Matrix metallopeptidase 9. (709 aa)
SPRED2Sprouty related EVH1 domain containing 2. (431 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1002 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa)
CTNNB1Catenin beta 1. (781 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa)
ENSPCOP00000025005Uncharacterized protein. (351 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
SIX2SIX homeobox 2. (296 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
GDF3Growth differentiation factor 3. (365 aa)
SPRY1Sprouty RTK signaling antagonist 1. (319 aa)
SPRY2Sprouty RTK signaling antagonist 2. (314 aa)
SRSF6Serine and arginine rich splicing factor 6. (345 aa)
SPRED1Sprouty related EVH1 domain containing 1. (444 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (789 aa)
NOTCH4Notch receptor 4. (2000 aa)
SOX9SRY-box transcription factor 9. (505 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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