STRINGSTRING
LHX5 LHX5 PTCH2 PTCH2 ENSPCOP00000013604 ENSPCOP00000013604 PROM1 PROM1 TP73 TP73 ENSPCOP00000013017 ENSPCOP00000013017 VDR VDR KDF1 KDF1 FOXN1 FOXN1 SERPINE1 SERPINE1 NKX2-2 NKX2-2 FOXJ1 FOXJ1 ENSPCOP00000006834 ENSPCOP00000006834 OVOL2 OVOL2 MACROH2A1 MACROH2A1 NOTCH1 NOTCH1 BMP7 BMP7 PAX2 PAX2 BTG1 BTG1 ETV4 ETV4 SFN SFN WNT10B WNT10B VEZF1 VEZF1 LIF LIF MESP1 MESP1 PAX4 PAX4 SFRP4 SFRP4 LHX1 LHX1 NCOA3 NCOA3 MED1 MED1 CYP27B1 CYP27B1 ETV2 ETV2 RFX3 RFX3 ATOH8 ATOH8 GDNF GDNF SULT2B1 SULT2B1 PTCH1 PTCH1 IL20 IL20 CTNNB1 CTNNB1 ACVRL1 ACVRL1 MACROH2A2 MACROH2A2 PLAAT4 PLAAT4 BMP4 BMP4 BMP6 BMP6 FOXC1 FOXC1 GDF2 GDF2 CDKN2B CDKN2B PAX6 PAX6 SOX9 SOX9 BAD BAD BMP2 BMP2 FGF2 FGF2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LHX5LIM homeobox 5. (402 aa)
PTCH2Patched 2. (1207 aa)
ENSPCOP00000013604Uncharacterized protein. (560 aa)
PROM1Prominin 1. (866 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (588 aa)
ENSPCOP00000013017Uncharacterized protein. (47 aa)
VDRVitamin D receptor. (474 aa)
KDF1Keratinocyte differentiation factor 1. (395 aa)
FOXN1Forkhead box N1. (648 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (402 aa)
NKX2-2NK2 homeobox 2. (273 aa)
FOXJ1Forkhead box J1. (421 aa)
ENSPCOP00000006834Uncharacterized protein. (78 aa)
OVOL2Ovo like zinc finger 2. (276 aa)
MACROH2A1Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
NOTCH1Notch receptor 1. (2420 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
PAX2Paired box 2. (417 aa)
BTG1BTG anti-proliferation factor 1. (171 aa)
ETV4ETS variant 4. (485 aa)
SFNStratifin; Belongs to the 14-3-3 family. (248 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
VEZF1Vascular endothelial zinc finger 1. (519 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
MESP1Mesoderm posterior bHLH transcription factor 1. (261 aa)
PAX4Paired box 4. (349 aa)
SFRP4Secreted frizzled related protein 4. (342 aa)
LHX1LIM homeobox 1. (406 aa)
NCOA3Nuclear receptor coactivator. (1410 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa)
ETV2ETS domain-containing protein. (153 aa)
RFX3Regulatory factor X3. (760 aa)
ATOH8Atonal bHLH transcription factor 8. (313 aa)
GDNFGlial cell derived neurotrophic factor. (228 aa)
SULT2B1Sulfotransferase; Belongs to the sulfotransferase 1 family. (337 aa)
PTCH1Patched 1. (1449 aa)
IL20Interleukin 20. (126 aa)
CTNNB1Catenin beta 1. (781 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
MACROH2A2Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
PLAAT4Phospholipase A and acyltransferase 4. (167 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
BMP6Bone morphogenetic protein 6. (509 aa)
FOXC1Forkhead box C1. (535 aa)
GDF2Growth differentiation factor 2. (427 aa)
CDKN2BCyclin dependent kinase inhibitor 2B. (138 aa)
PAX6Paired box 6. (453 aa)
SOX9SRY-box transcription factor 9. (505 aa)
BADBCL2 associated agonist of cell death. (168 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (394 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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