23 items (Propithecus coquereli) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	TG	Thyroglobulin. (2704 aa)
	EDN1	Endothelin 1. (193 aa)
	HESX1	HESX homeobox 1. (184 aa)
	NKX2-1	NK2 homeobox 1. (401 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
	SIX1	SIX homeobox 1. (284 aa)
	HOXD3	Homeobox D3. (432 aa)
	FGF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
	DUOX2	Dual oxidase 2. (1540 aa)
	NKX2-5	NK2 homeobox 5. (324 aa)
	PAX8	Paired box 8. (458 aa)
	HOXB3	Homeobox B3. (426 aa)
	HOXA5	Homeobox A5. (270 aa)
	TBX1	T-box transcription factor 1. (489 aa)
	ENSPCOP00000018033	HH_signal domain-containing protein. (110 aa)
	SRF	Serum response factor. (508 aa)
	SMAD3	Mothers against decapentaplegic homolog. (443 aa)
	BRAF	B-Raf proto-oncogene, serine/threonine kinase. (745 aa)
	HOXA3	Homeobox A3. (444 aa)
	THRA	Thyroid hormone receptor alpha. (645 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRAF	MAPK1	ENSPCOP00000024534	ENSPCOP00000029858	B-Raf proto-oncogene, serine/threonine kinase.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.848
BRAF	MAPK3	ENSPCOP00000024534	ENSPCOP00000008272	B-Raf proto-oncogene, serine/threonine kinase.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.862
DUOX2	MAPK1	ENSPCOP00000014556	ENSPCOP00000029858	Dual oxidase 2.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.436
DUOX2	MAPK3	ENSPCOP00000014556	ENSPCOP00000008272	Dual oxidase 2.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.436
EDN1	EDNRA	ENSPCOP00000006922	ENSPCOP00000029676	Endothelin 1.	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	0.998
EDN1	FGF8	ENSPCOP00000006922	ENSPCOP00000012774	Endothelin 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.509
EDN1	NKX2-5	ENSPCOP00000006922	ENSPCOP00000015558	Endothelin 1.	NK2 homeobox 5.	0.404
EDNRA	EDN1	ENSPCOP00000029676	ENSPCOP00000006922	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Endothelin 1.	0.998
EDNRA	MAPK1	ENSPCOP00000029676	ENSPCOP00000029858	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.449
ENSPCOP00000018033	FGF10	ENSPCOP00000018033	ENSPCOP00000001047	HH_signal domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.558
ENSPCOP00000018033	FGF8	ENSPCOP00000018033	ENSPCOP00000012774	HH_signal domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.612
FGF10	ENSPCOP00000018033	ENSPCOP00000001047	ENSPCOP00000018033	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	HH_signal domain-containing protein.	0.558
FGF10	FGF8	ENSPCOP00000001047	ENSPCOP00000012774	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.681
FGF10	MAPK1	ENSPCOP00000001047	ENSPCOP00000029858	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.494
FGF10	MAPK3	ENSPCOP00000001047	ENSPCOP00000008272	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.540
FGF8	EDN1	ENSPCOP00000012774	ENSPCOP00000006922	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Endothelin 1.	0.509
FGF8	ENSPCOP00000018033	ENSPCOP00000012774	ENSPCOP00000018033	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	HH_signal domain-containing protein.	0.612
FGF8	FGF10	ENSPCOP00000012774	ENSPCOP00000001047	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.681
FGF8	MAPK1	ENSPCOP00000012774	ENSPCOP00000029858	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.526
FGF8	MAPK3	ENSPCOP00000012774	ENSPCOP00000008272	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.569