STRINGSTRING
FGF10 FGF10 WNT2B WNT2B FRS2 FRS2 WNT4 WNT4 SOX8 SOX8 GDNF GDNF CTNNB1 CTNNB1 WNT3 WNT3 C12orf43 C12orf43 SPRY1 SPRY1 HIPK1 HIPK1 BMP4 BMP4 SOX9 SOX9 NKX2-1 NKX2-1 WNT2 WNT2 BMP2 BMP2 SALL1 SALL1 HOXA11 HOXA11 FGF8 FGF8 FGF1 FGF1 SIX1 SIX1 WNT1 WNT1 HOXC11 HOXC11 HIPK2 HIPK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
SOX8SRY-box transcription factor 8. (462 aa)
GDNFGlial cell derived neurotrophic factor. (228 aa)
CTNNB1Catenin beta 1. (781 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
C12orf43Chromosome 12 open reading frame 43. (294 aa)
SPRY1Sprouty RTK signaling antagonist 1. (319 aa)
HIPK1Homeodomain interacting protein kinase 1. (1131 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
SOX9SRY-box transcription factor 9. (505 aa)
NKX2-1NK2 homeobox 1. (401 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
SALL1Spalt like transcription factor 1. (1315 aa)
HOXA11Homeobox A11. (316 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
SIX1SIX homeobox 1. (284 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
HOXC11Homeobox C11. (369 aa)
HIPK2Homeodomain interacting protein kinase 2. (1187 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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