38 items (Propithecus coquereli) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SRC	Tyrosine-protein kinase. (543 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
	CSK	Tyrosine-protein kinase. (450 aa)
	DPP4	Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (766 aa)
	ENSPCOP00000031440	annotation not available (119 aa)
	EFNB1	Ephrin B1; Belongs to the ephrin family. (346 aa)
	EFNB2	Ephrin B2; Belongs to the ephrin family. (335 aa)
	ENSPCOP00000000722	Protein kinase domain-containing protein. (67 aa)
	CD80	CD80 molecule. (265 aa)
	ENSPCOP00000004985	Uncharacterized protein. (330 aa)
	TNFSF13B	TNF superfamily member 13b; Belongs to the tumor necrosis factor family. (244 aa)
	ENSPCOP00000006834	Uncharacterized protein. (78 aa)
	CD274	CD274 molecule. (244 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	CD3E	CD3e molecule. (187 aa)
	CD81	Tetraspanin. (271 aa)
	TNFSF14	TNF superfamily member 14. (241 aa)
	CD28	CD28 molecule. (220 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (607 aa)
	VAV1	Vav guanine nucleotide exchange factor 1. (806 aa)
	TNFRSF14	TNF receptor superfamily member 14. (267 aa)
	PIK3CA	Phosphatidylinositol 3-kinase catalytic subunit type 3. (933 aa)
	CARD11	Caspase recruitment domain family member 11. (1125 aa)
	EFNB3	Ephrin B3; Belongs to the ephrin family. (343 aa)
	ENSPCOP00000017161	Mitogen-activated protein kinase kinase kinase 8. (119 aa)
	CD160	CD160 molecule. (220 aa)
	CD86	CD86 molecule. (336 aa)
	ICOSLG	Uncharacterized protein. (299 aa)
	TMIGD2	Transmembrane and immunoglobulin domain containing 2. (225 aa)
	LGALS1	Galectin. (135 aa)
	CCL19	C-C motif chemokine. (108 aa)
	PDCD1LG2	Programmed cell death 1 ligand 2. (274 aa)
	LYN	Tyrosine-protein kinase. (512 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
	ICOS	Inducible T cell costimulator. (200 aa)
	TNFRSF13C	TNF receptor superfamily member 13C. (179 aa)
	CD5	CD5 molecule. (474 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	CARD11	ENSPCOP00000028969	ENSPCOP00000015614	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Caspase recruitment domain family member 11.	0.433
AKT1	CAV1	ENSPCOP00000028969	ENSPCOP00000025045	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.636
AKT1	CD28	ENSPCOP00000028969	ENSPCOP00000012951	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	CD28 molecule.	0.442
AKT1	CD80	ENSPCOP00000028969	ENSPCOP00000003595	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	CD80 molecule.	0.664
AKT1	CD86	ENSPCOP00000028969	ENSPCOP00000019857	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	CD86 molecule.	0.579
AKT1	CSK	ENSPCOP00000028969	ENSPCOP00000030390	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.673
AKT1	EFNB1	ENSPCOP00000028969	ENSPCOP00000031979	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Ephrin B1; Belongs to the ephrin family.	0.420
AKT1	EFNB2	ENSPCOP00000028969	ENSPCOP00000000273	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Ephrin B2; Belongs to the ephrin family.	0.451
AKT1	EFNB3	ENSPCOP00000028969	ENSPCOP00000016381	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Ephrin B3; Belongs to the ephrin family.	0.416
AKT1	ENSPCOP00000000722	ENSPCOP00000028969	ENSPCOP00000000722	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.764
AKT1	ENSPCOP00000017161	ENSPCOP00000028969	ENSPCOP00000017161	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase kinase 8.	0.823
AKT1	ENSPCOP00000031440	ENSPCOP00000028969	ENSPCOP00000031440	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	annotation not available	0.823
AKT1	FYN	ENSPCOP00000028969	ENSPCOP00000008529	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.755
AKT1	LYN	ENSPCOP00000028969	ENSPCOP00000024889	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.710
AKT1	PIK3CA	ENSPCOP00000028969	ENSPCOP00000015588	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.975
AKT1	PTPN11	ENSPCOP00000028969	ENSPCOP00000029437	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.582
AKT1	SRC	ENSPCOP00000028969	ENSPCOP00000018583	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.890
AKT1	VAV1	ENSPCOP00000028969	ENSPCOP00000014644	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Vav guanine nucleotide exchange factor 1.	0.729
CARD11	AKT1	ENSPCOP00000015614	ENSPCOP00000028969	Caspase recruitment domain family member 11.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.433
CARD11	FYN	ENSPCOP00000015614	ENSPCOP00000008529	Caspase recruitment domain family member 11.	Tyrosine-protein kinase.	0.413