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TAMM41 TAMM41 PLA2G6 PLA2G6 SLC27A1 SLC27A1 PNPLA8 PNPLA8 PGS1 PGS1 PLSCR3 PLSCR3 CRLS1 CRLS1 LCLAT1 LCLAT1 HADHA HADHA TAZ TAZ MECP2 MECP2 PTPMT1 PTPMT1 THEM5 THEM5 PLA2G5 PLA2G5
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
TAMM41Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane. (334 aa)
PLA2G6Phospholipase A2 group VI. (807 aa)
SLC27A1Solute carrier family 27 member 1. (646 aa)
PNPLA8Patatin like phospholipase domain containing 8. (614 aa)
PGS1CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family. (555 aa)
PLSCR3Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (295 aa)
CRLS1Cardiolipin synthase 1. (301 aa)
LCLAT1Lysocardiolipin acyltransferase 1. (340 aa)
HADHAHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa)
TAZTafazzin family protein; Some isoforms may be involved in cardiolipin metabolism. (280 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (500 aa)
PTPMT1Protein tyrosine phosphatase mitochondrial 1. (193 aa)
THEM5Thioesterase superfamily member 5. (244 aa)
PLA2G5Phospholipase A(2). (138 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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