33 items (Propithecus coquereli) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	POLR3A	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1390 aa)
	POLR1D	RNA polymerase I and III subunit D. (133 aa)
	PRIM1	DNA primase; Belongs to the eukaryotic-type primase small subunit family. (420 aa)
	ENSPCOP00000028798	Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (121 aa)
	POLR1A	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1721 aa)
	ENSPCOP00000028633	Uncharacterized protein. (58 aa)
	POLR2F	RNA polymerase II subunit F. (127 aa)
	POLR2A	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1978 aa)
	ENSPCOP00000025432	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (747 aa)
	POLR3C	RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (463 aa)
	POLR1C	RNA polymerase I and III subunit C. (346 aa)
	POLR2J	RNA_pol_L_2 domain-containing protein. (141 aa)
	POLR3G	Uncharacterized protein. (82 aa)
	TRNT1	tRNA nucleotidyl transferase 1; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (434 aa)
	ENSPCOP00000015216	Uncharacterized protein. (68 aa)
	POLR3K	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (108 aa)
	POLR2I	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
	TWISTNB	TWIST neighbor. (337 aa)
	POLR2C	RNA polymerase II subunit C. (275 aa)
	POLR1B	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1183 aa)
	ENSPCOP00000008287	Uncharacterized protein. (126 aa)
	POLRMT	DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. (1217 aa)
	POLR2E	RNA polymerase II subunit E. (210 aa)
	POLR3B	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1085 aa)
	POLR3H	RNA polymerase III subunit H. (204 aa)
	ENSPCOP00000003049	Uncharacterized protein. (437 aa)
	ENSPCOP00000002776	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (330 aa)
	ENSPCOP00000002346	Uncharacterized protein. (58 aa)
	LOC105822452	Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (144 aa)
	POLR3F	DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (316 aa)
	TENT2	Terminal nucleotidyltransferase 2. (411 aa)
	ENSPCOP00000031731	Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (127 aa)
	LOC105823602	Uncharacterized protein. (95 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPCOP00000002346	ENSPCOP00000003049	ENSPCOP00000002346	ENSPCOP00000003049	Uncharacterized protein.	Uncharacterized protein.	0.985
ENSPCOP00000002346	ENSPCOP00000008287	ENSPCOP00000002346	ENSPCOP00000008287	Uncharacterized protein.	Uncharacterized protein.	0.945
ENSPCOP00000002346	ENSPCOP00000028798	ENSPCOP00000002346	ENSPCOP00000028798	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.785
ENSPCOP00000002346	ENSPCOP00000031731	ENSPCOP00000002346	ENSPCOP00000031731	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.785
ENSPCOP00000002346	LOC105822452	ENSPCOP00000002346	ENSPCOP00000002034	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.785
ENSPCOP00000002346	LOC105823602	ENSPCOP00000002346	ENSPCOP00000032148	Uncharacterized protein.	Uncharacterized protein.	0.976
ENSPCOP00000002346	POLR1A	ENSPCOP00000002346	ENSPCOP00000028640	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.980
ENSPCOP00000002346	POLR1B	ENSPCOP00000002346	ENSPCOP00000009037	Uncharacterized protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.981
ENSPCOP00000002346	POLR1C	ENSPCOP00000002346	ENSPCOP00000024838	Uncharacterized protein.	RNA polymerase I and III subunit C.	0.984
ENSPCOP00000002346	POLR1D	ENSPCOP00000002346	ENSPCOP00000030856	Uncharacterized protein.	RNA polymerase I and III subunit D.	0.985
ENSPCOP00000002346	POLR2A	ENSPCOP00000002346	ENSPCOP00000025964	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.984
ENSPCOP00000002346	POLR2C	ENSPCOP00000002346	ENSPCOP00000011525	Uncharacterized protein.	RNA polymerase II subunit C.	0.984
ENSPCOP00000002346	POLR2E	ENSPCOP00000002346	ENSPCOP00000006636	Uncharacterized protein.	RNA polymerase II subunit E.	0.988
ENSPCOP00000002346	POLR2F	ENSPCOP00000002346	ENSPCOP00000026634	Uncharacterized protein.	RNA polymerase II subunit F.	0.976
ENSPCOP00000002346	POLR2I	ENSPCOP00000002346	ENSPCOP00000013967	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.985
ENSPCOP00000002346	POLR2J	ENSPCOP00000002346	ENSPCOP00000024723	Uncharacterized protein.	RNA_pol_L_2 domain-containing protein.	0.989
ENSPCOP00000002346	POLR3A	ENSPCOP00000002346	ENSPCOP00000031126	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.981
ENSPCOP00000002346	POLR3B	ENSPCOP00000002346	ENSPCOP00000006626	Uncharacterized protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.979
ENSPCOP00000002346	POLR3C	ENSPCOP00000002346	ENSPCOP00000025425	Uncharacterized protein.	RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.981
ENSPCOP00000002346	POLR3F	ENSPCOP00000002346	ENSPCOP00000001439	Uncharacterized protein.	DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.	0.945