STRINGSTRING
ANGPT1 ANGPT1 SH3GL2 SH3GL2 GJA1 GJA1 JAM3 JAM3 CDH5 CDH5 TJP3 TJP3 SLC12A2 SLC12A2 ENSPCOP00000014148 ENSPCOP00000014148 ABCC8 ABCC8 TJP1 TJP1 PTGS2 PTGS2 LAMC1 LAMC1 VCL VCL GJB6 GJB6 SLC1A1 SLC1A1 MFSD2A MFSD2A JAM2 JAM2 CLDN1 CLDN1 ENSPCOP00000027120 ENSPCOP00000027120 LOC105826394 LOC105826394 WNK3 WNK3 VEGFA VEGFA MBP MBP LAMA2 LAMA2 LSR LSR OCLN OCLN PECAM1 PECAM1 F11R F11R LOC105826393 LOC105826393
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANGPT1Angiopoietin 1. (408 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (352 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
JAM3Junctional adhesion molecule 3. (310 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (786 aa)
TJP3Tight junction protein 3; Belongs to the MAGUK family. (922 aa)
SLC12A2Solute carrier family 12 member 2. (1153 aa)
ENSPCOP00000014148Uncharacterized protein. (733 aa)
ABCC8ATP binding cassette subfamily C member 8. (1582 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1768 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
LAMC1Laminin subunit gamma 1. (1494 aa)
VCLVinculin. (1134 aa)
GJB6Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (261 aa)
SLC1A1Amino acid transporter. (524 aa)
MFSD2AMajor facilitator superfamily domain containing 2A. (529 aa)
JAM2Junctional adhesion molecule 2. (261 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
ENSPCOP00000027120Uncharacterized protein. (1243 aa)
LOC105826394Claudin-12. (244 aa)
WNK3WNK lysine deficient protein kinase 3. (1791 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa)
MBPMyelin basic protein. (302 aa)
LAMA2Laminin subunit alpha 2. (2944 aa)
LSRLipolysis stimulated lipoprotein receptor. (619 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (516 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (698 aa)
F11RF11 receptor. (296 aa)
LOC105826393Uncharacterized protein. (244 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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