STRINGSTRING
CORT CORT BARD1 BARD1 ANKLE1 ANKLE1 MEIOB MEIOB MLH3 MLH3 PSMC3IP PSMC3IP RAD21 RAD21 LOC105825816 LOC105825816 TOP2B TOP2B C19orf57 C19orf57 MLH1 MLH1 ERCC4 ERCC4 FANCD2 FANCD2 FANCM FANCM TRIP13 TRIP13 C1orf146 C1orf146 RAD51 RAD51 HSF2BP HSF2BP RAD54L RAD54L ENSPCOP00000008609 ENSPCOP00000008609 ENSPCOP00000009092 ENSPCOP00000009092 CCNB1IP1 CCNB1IP1 SYCP1 SYCP1 TEX11 TEX11 SLX4 SLX4 C14orf39 C14orf39 RNF212B RNF212B ANKRD31 ANKRD31 RBBP8 RBBP8 HDAC10 HDAC10 REC8 REC8 MUS81 MUS81 SYCE3 SYCE3 ATM ATM EME2 EME2 SPO11 SPO11 RNF212 RNF212 UBR2 UBR2 CNTD1 CNTD1 CENPX CENPX TOPBP1 TOPBP1 MSH5 MSH5 RAD51C RAD51C RAD51B RAD51B KLHDC3 KLHDC3 DMC1 DMC1 TOP2A TOP2A ENSPCOP00000027504 ENSPCOP00000027504 MND1 MND1 FSBP FSBP C11orf80 C11orf80 MSH4 MSH4 SHOC1 SHOC1 CENPS CENPS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CORTCortistatin. (105 aa)
BARD1BRCA1 associated RING domain 1. (769 aa)
ANKLE1Ankyrin repeat and LEM domain containing 1. (624 aa)
MEIOBMeiosis specific with OB-fold. (289 aa)
MLH3MutL homolog 3. (1456 aa)
PSMC3IPPSMC3 interacting protein. (217 aa)
RAD21RAD21 cohesin complex component. (631 aa)
LOC105825816ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family. (229 aa)
TOP2BDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1623 aa)
C19orf57Chromosome 19 open reading frame 57. (666 aa)
MLH1MutL homolog 1. (757 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (879 aa)
FANCD2FA complementation group D2. (1424 aa)
FANCMFA complementation group M. (1953 aa)
TRIP13AAA domain-containing protein; Belongs to the AAA ATPase family. (434 aa)
C1orf146Chromosome 1 open reading frame 146. (181 aa)
RAD51RAD51 recombinase; Belongs to the RecA family. (340 aa)
HSF2BPHeat shock transcription factor 2 binding protein. (334 aa)
RAD54LRAD54 like. (747 aa)
ENSPCOP00000008609Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (172 aa)
ENSPCOP00000009092E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (366 aa)
CCNB1IP1Cyclin B1 interacting protein 1. (277 aa)
SYCP1Synaptonemal complex protein 1. (767 aa)
TEX11Testis expressed 11. (895 aa)
SLX4SLX4 structure-specific endonuclease subunit. (1806 aa)
C14orf39Chromosome 14 open reading frame 39. (566 aa)
RNF212BRing finger protein 212B. (300 aa)
ANKRD31Ankyrin repeat domain 31. (1863 aa)
RBBP8RB binding protein 8, endonuclease. (865 aa)
HDAC10Histone deacetylase 10. (669 aa)
REC8REC8 meiotic recombination protein. (560 aa)
MUS81MUS81 structure-specific endonuclease subunit. (551 aa)
SYCE3Synaptonemal complex central element protein 3. (88 aa)
ATMATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2635 aa)
EME2Essential meiotic structure-specific endonuclease subunit 2. (374 aa)
SPO11SPO11 initiator of meiotic double stranded breaks. (285 aa)
RNF212Uncharacterized protein. (237 aa)
UBR2E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1482 aa)
CNTD1Cyclin N-terminal domain containing 1. (331 aa)
CENPXUncharacterized protein. (79 aa)
TOPBP1DNA topoisomerase II binding protein 1. (1394 aa)
MSH5DNA_MISMATCH_REPAIR_2 domain-containing protein. (836 aa)
RAD51CRAD51 paralog C. (368 aa)
RAD51BRECA_2 domain-containing protein. (199 aa)
KLHDC3Kelch domain containing 3. (382 aa)
DMC1Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (325 aa)
TOP2ADNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1526 aa)
ENSPCOP00000027504DEAD domain-containing protein. (414 aa)
MND1Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (185 aa)
FSBPUncharacterized protein. (911 aa)
C11orf80Chromosome 11 open reading frame 80. (468 aa)
MSH4MutS homolog 4. (834 aa)
SHOC1Shortage in chiasmata 1. (1102 aa)
CENPSCentromere protein S. (138 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.