STRINGSTRING
LIMK1 LIMK1 PLPP4 PLPP4 PRKCD PRKCD PRKCE PRKCE PTK2 PTK2 LYN LYN VAV3 VAV3 SRC SRC FGR FGR VAV1 VAV1 SYK SYK FYN FYN VAV2 VAV2 PLA2G6 PLA2G6 PAK1 PAK1 PLD2 PLD2 MYO1G MYO1G ENSPCOP00000000722 ENSPCOP00000000722
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LIMK1LIM domain kinase 1. (678 aa)
PLPP4Phospholipid phosphatase 4. (271 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
PTK2Protein tyrosine kinase 2. (1089 aa)
LYNTyrosine-protein kinase. (512 aa)
VAV3Vav guanine nucleotide exchange factor 3. (765 aa)
SRCTyrosine-protein kinase. (543 aa)
FGRTyrosine-protein kinase. (495 aa)
VAV1Vav guanine nucleotide exchange factor 1. (806 aa)
SYKSpleen associated tyrosine kinase. (637 aa)
FYNTyrosine-protein kinase. (537 aa)
VAV2Vav guanine nucleotide exchange factor 2. (771 aa)
PLA2G6Phospholipase A2 group VI. (807 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
PLD2Phospholipase. (932 aa)
MYO1GMyosin IG; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1018 aa)
ENSPCOP00000000722Protein kinase domain-containing protein. (67 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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