18 items (Propithecus coquereli) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	LIMK1	LIM domain kinase 1. (678 aa)
	PLPP4	Phospholipid phosphatase 4. (271 aa)
	PRKCD	Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
	PRKCE	Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
	PTK2	Protein tyrosine kinase 2. (1089 aa)
	LYN	Tyrosine-protein kinase. (512 aa)
	VAV3	Vav guanine nucleotide exchange factor 3. (765 aa)
	SRC	Tyrosine-protein kinase. (543 aa)
	FGR	Tyrosine-protein kinase. (495 aa)
	VAV1	Vav guanine nucleotide exchange factor 1. (806 aa)
	SYK	Spleen associated tyrosine kinase. (637 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	VAV2	Vav guanine nucleotide exchange factor 2. (771 aa)
	PLA2G6	Phospholipase A2 group VI. (807 aa)
	PAK1	Non-specific serine/threonine protein kinase. (544 aa)
	PLD2	Phospholipase. (932 aa)
	MYO1G	Myosin IG; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1018 aa)
	ENSPCOP00000000722	Protein kinase domain-containing protein. (67 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPCOP00000000722	FGR	ENSPCOP00000000722	ENSPCOP00000018420	Protein kinase domain-containing protein.	Tyrosine-protein kinase.	0.894
ENSPCOP00000000722	FYN	ENSPCOP00000000722	ENSPCOP00000008529	Protein kinase domain-containing protein.	Tyrosine-protein kinase.	0.990
ENSPCOP00000000722	LIMK1	ENSPCOP00000000722	ENSPCOP00000017003	Protein kinase domain-containing protein.	LIM domain kinase 1.	0.555
ENSPCOP00000000722	LYN	ENSPCOP00000000722	ENSPCOP00000024889	Protein kinase domain-containing protein.	Tyrosine-protein kinase.	0.887
ENSPCOP00000000722	PAK1	ENSPCOP00000000722	ENSPCOP00000007537	Protein kinase domain-containing protein.	Non-specific serine/threonine protein kinase.	0.619
ENSPCOP00000000722	PLD2	ENSPCOP00000000722	ENSPCOP00000001346	Protein kinase domain-containing protein.	Phospholipase.	0.463
ENSPCOP00000000722	PRKCD	ENSPCOP00000000722	ENSPCOP00000026438	Protein kinase domain-containing protein.	Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.857
ENSPCOP00000000722	PRKCE	ENSPCOP00000000722	ENSPCOP00000026275	Protein kinase domain-containing protein.	Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...]	0.517
ENSPCOP00000000722	PTK2	ENSPCOP00000000722	ENSPCOP00000025691	Protein kinase domain-containing protein.	Protein tyrosine kinase 2.	0.981
ENSPCOP00000000722	SRC	ENSPCOP00000000722	ENSPCOP00000018583	Protein kinase domain-containing protein.	Tyrosine-protein kinase.	0.959
ENSPCOP00000000722	SYK	ENSPCOP00000000722	ENSPCOP00000009462	Protein kinase domain-containing protein.	Spleen associated tyrosine kinase.	0.912
ENSPCOP00000000722	VAV1	ENSPCOP00000000722	ENSPCOP00000014644	Protein kinase domain-containing protein.	Vav guanine nucleotide exchange factor 1.	0.712
ENSPCOP00000000722	VAV2	ENSPCOP00000000722	ENSPCOP00000007849	Protein kinase domain-containing protein.	Vav guanine nucleotide exchange factor 2.	0.712
ENSPCOP00000000722	VAV3	ENSPCOP00000000722	ENSPCOP00000019353	Protein kinase domain-containing protein.	Vav guanine nucleotide exchange factor 3.	0.707
FGR	ENSPCOP00000000722	ENSPCOP00000018420	ENSPCOP00000000722	Tyrosine-protein kinase.	Protein kinase domain-containing protein.	0.894
FGR	LIMK1	ENSPCOP00000018420	ENSPCOP00000017003	Tyrosine-protein kinase.	LIM domain kinase 1.	0.596
FGR	LYN	ENSPCOP00000018420	ENSPCOP00000024889	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.942
FGR	PAK1	ENSPCOP00000018420	ENSPCOP00000007537	Tyrosine-protein kinase.	Non-specific serine/threonine protein kinase.	0.618
FGR	PRKCD	ENSPCOP00000018420	ENSPCOP00000026438	Tyrosine-protein kinase.	Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.622
FGR	PRKCE	ENSPCOP00000018420	ENSPCOP00000026275	Tyrosine-protein kinase.	Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...]	0.496