42 items (Propithecus coquereli) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	ATP5F1B	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (529 aa)
	UQCC2	Ubiquinol-cytochrome c reductase complex assembly factor 2. (136 aa)
	DNAJA3	DnaJ heat shock protein family (Hsp40) member A3. (429 aa)
	SHMT2	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa)
	POLG	DNA polymerase gamma, catalytic subunit. (1224 aa)
	TEFM	Transcription elongation factor, mitochondrial. (359 aa)
	CPS1	Carbamoyl-phosphate synthase 1. (1310 aa)
	VDAC1	Uncharacterized protein. (283 aa)
	LOC105807634	Uncharacterized protein; Belongs to the heat shock protein 70 family. (673 aa)
	SUPV3L1	Suv3 like RNA helicase. (667 aa)
	TFAM	Transcription factor A, mitochondrial. (246 aa)
	POLDIP2	DNA polymerase delta interacting protein 2. (368 aa)
	ENSPCOP00000006829	Uncharacterized protein. (252 aa)
	TWNK	Twinkle mtDNA helicase. (669 aa)
	TFB2M	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (379 aa)
	HSD17B10	Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa)
	LONP1	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...] (960 aa)
	SSBP1	Single stranded DNA binding protein 1. (148 aa)
	ACADVL	Acyl-CoA dehydrogenase very long chain. (677 aa)
	HSPA9	Uncharacterized protein; Belongs to the heat shock protein 70 family. (506 aa)
	LRRC59	Leucine rich repeat containing 59. (307 aa)
	MPG	N-methylpurine DNA glycosylase. (284 aa)
	ELAC2	ElaC ribonuclease Z 2. (823 aa)
	POLRMT	DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. (1217 aa)
	MTERF1	Mitochondrial transcription termination factor 1. (396 aa)
	TUFM	Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (455 aa)
	VDAC2	Voltage dependent anion channel 2. (309 aa)
	ENSPCOP00000002776	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (330 aa)
	LRPPRC	Leucine rich pentatricopeptide repeat containing. (1386 aa)
	FASTKD2	FAST kinase domains 2. (608 aa)
	TFB1M	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (345 aa)
	DNA2	Uncharacterized protein. (833 aa)
	GRSF1	G-rich RNA sequence binding factor 1. (329 aa)
	TOP1MT	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (503 aa)
	DHX30	DExH-box helicase 30. (1222 aa)
	ENSPCOP00000025432	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (747 aa)
	POLG2	DNA polymerase gamma 2, accessory subunit. (465 aa)
	DDX28	DEAD-box helicase 28. (541 aa)
	ENSPCOP00000024841	Uncharacterized protein. (84 aa)
	CLPX	Caseinolytic mitochondrial matrix peptidase chaperone subunit. (531 aa)
	DBT	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (458 aa)
	HADHA	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACADVL	DBT	ENSPCOP00000017826	ENSPCOP00000024422	Acyl-CoA dehydrogenase very long chain.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.753
ACADVL	HADHA	ENSPCOP00000017826	ENSPCOP00000018962	Acyl-CoA dehydrogenase very long chain.	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family.	0.974
ACADVL	HSD17B10	ENSPCOP00000017826	ENSPCOP00000012250	Acyl-CoA dehydrogenase very long chain.	Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.418
ATP5F1B	DNAJA3	ENSPCOP00000010115	ENSPCOP00000024144	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	DnaJ heat shock protein family (Hsp40) member A3.	0.519
ATP5F1B	ENSPCOP00000006829	ENSPCOP00000010115	ENSPCOP00000006829	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Uncharacterized protein.	0.703
ATP5F1B	HSPA9	ENSPCOP00000010115	ENSPCOP00000017752	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.612
ATP5F1B	LOC105807634	ENSPCOP00000010115	ENSPCOP00000019164	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.612
ATP5F1B	TUFM	ENSPCOP00000010115	ENSPCOP00000004145	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.905
ATP5F1B	VDAC1	ENSPCOP00000010115	ENSPCOP00000019628	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Uncharacterized protein.	0.703
ATP5F1B	VDAC2	ENSPCOP00000010115	ENSPCOP00000004108	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Voltage dependent anion channel 2.	0.689
CLPX	CPS1	ENSPCOP00000024556	ENSPCOP00000020028	Caseinolytic mitochondrial matrix peptidase chaperone subunit.	Carbamoyl-phosphate synthase 1.	0.503
CLPX	DNAJA3	ENSPCOP00000024556	ENSPCOP00000024144	Caseinolytic mitochondrial matrix peptidase chaperone subunit.	DnaJ heat shock protein family (Hsp40) member A3.	0.546
CLPX	HSPA9	ENSPCOP00000024556	ENSPCOP00000017752	Caseinolytic mitochondrial matrix peptidase chaperone subunit.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.445
CLPX	LOC105807634	ENSPCOP00000024556	ENSPCOP00000019164	Caseinolytic mitochondrial matrix peptidase chaperone subunit.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.445
CLPX	LONP1	ENSPCOP00000024556	ENSPCOP00000013476	Caseinolytic mitochondrial matrix peptidase chaperone subunit.	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...]	0.834
CLPX	SSBP1	ENSPCOP00000024556	ENSPCOP00000018234	Caseinolytic mitochondrial matrix peptidase chaperone subunit.	Single stranded DNA binding protein 1.	0.584
CLPX	TFB1M	ENSPCOP00000024556	ENSPCOP00000031366	Caseinolytic mitochondrial matrix peptidase chaperone subunit.	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.	0.441
CLPX	TFB2M	ENSPCOP00000024556	ENSPCOP00000012108	Caseinolytic mitochondrial matrix peptidase chaperone subunit.	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.	0.453
CLPX	TUFM	ENSPCOP00000024556	ENSPCOP00000004145	Caseinolytic mitochondrial matrix peptidase chaperone subunit.	Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.685
CPS1	CLPX	ENSPCOP00000020028	ENSPCOP00000024556	Carbamoyl-phosphate synthase 1.	Caseinolytic mitochondrial matrix peptidase chaperone subunit.	0.503