43 items (Propithecus coquereli) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TEK	TEK receptor tyrosine kinase. (1125 aa)
	CHRM4	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (478 aa)
	OCLN	Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (516 aa)
	TACR2	Tachykinin receptor 2; Belongs to the G-protein coupled receptor 1 family. (398 aa)
	ADORA2A	Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (411 aa)
	ENSPCOP00000000722	Protein kinase domain-containing protein. (67 aa)
	GPR4	G protein-coupled receptor 4; Belongs to the G-protein coupled receptor 1 family. (362 aa)
	TRPV4	Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (870 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	PLEC	Plectin. (4689 aa)
	ANGPT1	Angiopoietin 1. (408 aa)
	RAMP2	Receptor activity modifying protein 2. (179 aa)
	CDH5	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (786 aa)
	SRC	Tyrosine-protein kinase. (543 aa)
	TJP3	Tight junction protein 3; Belongs to the MAGUK family. (922 aa)
	BCR	BCR activator of RhoGEF and GTPase. (1168 aa)
	CTNNBIP1	Catenin beta interacting protein 1. (81 aa)
	AZU1	Azurocidin 1. (250 aa)
	PDE3A	Phosphodiesterase. (1073 aa)
	PTP4A3	Protein tyrosine phosphatase 4A3. (173 aa)
	CEACAM1	Uncharacterized protein. (523 aa)
	ABCC8	ATP binding cassette subfamily C member 8. (1582 aa)
	SLIT2	Slit guidance ligand 2. (1423 aa)
	PTPRJ	Protein tyrosine phosphatase receptor type J. (1223 aa)
	TACR1	Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
	TJP1	Tight junction protein 1; Belongs to the MAGUK family. (1768 aa)
	FERMT2	Fermitin family member 2. (693 aa)
	MYLK3	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (496 aa)
	NPR1	Guanylate cyclase. (1058 aa)
	C2CD4A	Uncharacterized protein. (367 aa)
	AKAP12	A-kinase anchoring protein 12. (1773 aa)
	APOE	Apolipoprotein E. (314 aa)
	ARHGAP35	Rho GTPase activating protein 35. (1510 aa)
	BDKRB2	Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (393 aa)
	DDAH1	Dimethylarginine dimethylaminohydrolase 1. (285 aa)
	SH3GL2	SH3 domain containing GRB2 like 2, endophilin A1. (352 aa)
	NPPB	Natriuretic peptide B. (132 aa)
	BMP6	Bone morphogenetic protein 6. (509 aa)
	AMOT	Angiomotin. (1083 aa)
	PDE2A	Phosphodiesterase. (940 aa)
	ENSPCOP00000024480	Uncharacterized protein. (103 aa)
	ADM	Adrenomedullin. (182 aa)
	VEGFA	Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADM	ADORA2A	ENSPCOP00000024146	ENSPCOP00000002230	Adrenomedullin.	Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.	0.414
ADM	RAMP2	ENSPCOP00000024146	ENSPCOP00000019093	Adrenomedullin.	Receptor activity modifying protein 2.	0.993
ADORA2A	ADM	ENSPCOP00000002230	ENSPCOP00000024146	Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.	Adrenomedullin.	0.414
ADORA2A	CHRM4	ENSPCOP00000002230	ENSPCOP00000005629	Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	0.404
ANGPT1	CDH5	ENSPCOP00000021737	ENSPCOP00000018940	Angiopoietin 1.	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	0.429
ANGPT1	TEK	ENSPCOP00000021737	ENSPCOP00000008595	Angiopoietin 1.	TEK receptor tyrosine kinase.	0.995
ARHGAP35	ENSPCOP00000000722	ENSPCOP00000008940	ENSPCOP00000000722	Rho GTPase activating protein 35.	Protein kinase domain-containing protein.	0.817
ARHGAP35	SRC	ENSPCOP00000008940	ENSPCOP00000018583	Rho GTPase activating protein 35.	Tyrosine-protein kinase.	0.883
AZU1	SH3GL2	ENSPCOP00000015621	ENSPCOP00000029897	Azurocidin 1.	SH3 domain containing GRB2 like 2, endophilin A1.	0.781
BCR	TJP1	ENSPCOP00000016599	ENSPCOP00000012159	BCR activator of RhoGEF and GTPase.	Tight junction protein 1; Belongs to the MAGUK family.	0.482
BCR	TJP3	ENSPCOP00000016599	ENSPCOP00000016885	BCR activator of RhoGEF and GTPase.	Tight junction protein 3; Belongs to the MAGUK family.	0.475
C2CD4A	SH3GL2	ENSPCOP00000011701	ENSPCOP00000029897	Uncharacterized protein.	SH3 domain containing GRB2 like 2, endophilin A1.	0.420
CDH5	ANGPT1	ENSPCOP00000018940	ENSPCOP00000021737	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	Angiopoietin 1.	0.429
CDH5	OCLN	ENSPCOP00000018940	ENSPCOP00000003158	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family.	0.592
CDH5	PLEC	ENSPCOP00000018940	ENSPCOP00000022391	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	Plectin.	0.409
CDH5	PTPRJ	ENSPCOP00000018940	ENSPCOP00000012702	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	Protein tyrosine phosphatase receptor type J.	0.620
CDH5	SRC	ENSPCOP00000018940	ENSPCOP00000018583	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	Tyrosine-protein kinase.	0.533
CDH5	TEK	ENSPCOP00000018940	ENSPCOP00000008595	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	TEK receptor tyrosine kinase.	0.639
CDH5	TJP1	ENSPCOP00000018940	ENSPCOP00000012159	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	Tight junction protein 1; Belongs to the MAGUK family.	0.752
CDH5	TJP3	ENSPCOP00000018940	ENSPCOP00000016885	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	Tight junction protein 3; Belongs to the MAGUK family.	0.527