STRINGSTRING
TRIM25 TRIM25 LAMTOR5 LAMTOR5 LURAP1L LURAP1L BIRC2 BIRC2 IKBKB IKBKB INAVA INAVA EDAR EDAR CX3CL1 CX3CL1 MIB2 MIB2 LURAP1 LURAP1 UBE2I UBE2I NDFIP2 NDFIP2 MAVS MAVS PELI2 PELI2 CASP10 CASP10 NEK6 NEK6 TSPAN6 TSPAN6 LOC105826747 LOC105826747 TBK1 TBK1 TRADD TRADD MAP3K3 MAP3K3 PRKN PRKN TICAM1 TICAM1 PRKCE PRKCE CD40 CD40 CLEC7A CLEC7A PPP5C PPP5C FASLG FASLG ENSPCOP00000025645 ENSPCOP00000025645 ALPK1 ALPK1 PINK1 PINK1 RIPK2 RIPK2 MAP3K14 MAP3K14 RIPK1 RIPK1 TNFRSF19 TNFRSF19 TNFSF10 TNFSF10 CCL19 CCL19 CASP8 CASP8 REL REL PPM1A PPM1A LGALS1 LGALS1 TIRAP TIRAP S100A13 S100A13 CLEC4D CLEC4D CCDC22 CCDC22 GPRC5B GPRC5B AKAP13 AKAP13 IRAK4 IRAK4 S100A4 S100A4 RBCK1 RBCK1 ECT2 ECT2 ECM1 ECM1 NOD2 NOD2 IRAK1 IRAK1 ENSPCOP00000029405 ENSPCOP00000029405 PRKCB PRKCB CHUK CHUK HTR2B HTR2B SHARPIN SHARPIN MYD88 MYD88 CARD11 CARD11 TNF TNF TNIP2 TNIP2 ANKRD17 ANKRD17 TRAF2 TRAF2 DDX21 DDX21 CASP1 CASP1 ENSPCOP00000013979 ENSPCOP00000013979 TRIM62 TRIM62 CTNNB1 CTNNB1 ENSPCOP00000000026 ENSPCOP00000000026 CCL21 CCL21 ENSPCOP00000000471 ENSPCOP00000000471 TRIM8 TRIM8 TRAF6 TRAF6 LITAF LITAF LTBR LTBR TRIM5 TRIM5 TRIM32 TRIM32 PRKD1 PRKD1 BIRC3 BIRC3 TMEM9B TMEM9B FLNA FLNA LOC105806826 LOC105806826 DHX36 DHX36 DDX50 DDX50 ENSPCOP00000004429 ENSPCOP00000004429 PLEKHG5 PLEKHG5 TRIML1 TRIML1 TFG TFG GOLT1B GOLT1B ROR1 ROR1 EDA EDA LTF LTF TRIM52 TRIM52 IRF3 IRF3 MID2 MID2 MAP3K7 MAP3K7 TRIM6 TRIM6 RHOA RHOA MTDH MTDH BRD4 BRD4 ENSPCOP00000006977 ENSPCOP00000006977 UBD UBD GAPDH GAPDH FYN FYN CD4 CD4 EDA2R EDA2R TLR3 TLR3 AJUBA AJUBA RNF31 RNF31 CD74 CD74 ATP2C1 ATP2C1 CLEC6A CLEC6A TRAF3IP2 TRAF3IP2 CCR7 CCR7 LPAR1 LPAR1 S100A12 S100A12 CD36 CD36 CC2D1A CC2D1A DHX15 DHX15 PELI1 PELI1 RHOC RHOC CANT1 CANT1 NDFIP1 NDFIP1 JMJD8 JMJD8 TMED4 TMED4 TRIM14 TRIM14 MUL1 MUL1 TAB3 TAB3 TRIM27 TRIM27 ADIPOQ ADIPOQ TMEM101 TMEM101 ZDHHC17 ZDHHC17 S100B S100B RELA RELA C18orf32 C18orf32 ABL1 ABL1 CARD9 CARD9 UNC5CL UNC5CL NOD1 NOD1 TNFSF11 TNFSF11 LOC105815151 LOC105815151 TMEM106A TMEM106A TRAF5 TRAF5 MALT1 MALT1 DDX1 DDX1 TAB2 TAB2 FADD FADD TRIML2 TRIML2 GJA1 GJA1 LOC105826437 LOC105826437 IKBKE IKBKE TNFRSF1A TNFRSF1A TERF2IP TERF2IP IKBKG IKBKG LOC105822932 LOC105822932 TFRC TFRC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TRIM25Tripartite motif containing 25. (633 aa)
LAMTOR5Uncharacterized protein. (149 aa)
LURAP1LLeucine rich adaptor protein 1 like. (226 aa)
BIRC2Baculoviral IAP repeat containing 2. (619 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (747 aa)
INAVAInnate immunity activator. (662 aa)
EDAREctodysplasin A receptor. (463 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (405 aa)
MIB2Mindbomb E3 ubiquitin protein ligase 2. (987 aa)
LURAP1Leucine rich adaptor protein 1. (239 aa)
UBE2IUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
NDFIP2Nedd4 family interacting protein 2. (336 aa)
MAVSMitochondrial antiviral signaling protein. (514 aa)
PELI2Pellino E3 ubiquitin protein ligase family member 2. (386 aa)
CASP10Caspase 10; Belongs to the peptidase C14A family. (528 aa)
NEK6NIMA related kinase 6; Belongs to the protein kinase superfamily. (313 aa)
TSPAN6Tetraspanin. (246 aa)
LOC105826747Gp_dh_N domain-containing protein. (313 aa)
TBK1TANK binding kinase 1. (690 aa)
TRADDTNFRSF1A associated via death domain. (309 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (653 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (460 aa)
TICAM1TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (692 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
CD40CD40 molecule. (281 aa)
CLEC7AUncharacterized protein. (62 aa)
PPP5CSerine/threonine-protein phosphatase. (499 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (278 aa)
ENSPCOP00000025645Uncharacterized protein. (162 aa)
ALPK1Alpha kinase 1. (1234 aa)
PINK1PTEN induced kinase 1. (581 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (539 aa)
MAP3K14Uncharacterized protein. (151 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (643 aa)
TNFRSF19TNF receptor superfamily member 19. (394 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (288 aa)
CCL19C-C motif chemokine. (108 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (395 aa)
RELREL proto-oncogene, NF-kB subunit. (592 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa)
LGALS1Galectin. (135 aa)
TIRAPTIR domain containing adaptor protein. (198 aa)
S100A13S100 calcium binding protein A13; Belongs to the S-100 family. (99 aa)
CLEC4DC-type lectin domain family 4 member D. (215 aa)
CCDC22Coiled-coil domain containing 22. (627 aa)
GPRC5BG protein-coupled receptor class C group 5 member B. (404 aa)
AKAP13A-kinase anchoring protein 13. (2786 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (406 aa)
S100A4Protein S100; Belongs to the S-100 family. (101 aa)
RBCK1RANBP2-type and C3HC4-type zinc finger containing 1. (510 aa)
ECT2Epithelial cell transforming 2. (598 aa)
ECM1Extracellular matrix protein 1. (570 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1040 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (713 aa)
ENSPCOP00000029405UBIQUITIN_CONJUGAT_2 domain-containing protein. (155 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (682 aa)
HTR2B5-hydroxytryptamine receptor 2B. (480 aa)
SHARPINSHANK associated RH domain interactor. (379 aa)
MYD88MYD88 innate immune signal transduction adaptor. (353 aa)
CARD11Caspase recruitment domain family member 11. (1125 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (235 aa)
TNIP2TNFAIP3 interacting protein 2. (432 aa)
ANKRD17Ankyrin repeat domain 17. (2391 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
DDX21DExD-box helicase 21. (758 aa)
CASP1Uncharacterized protein; Belongs to the peptidase C14A family. (254 aa)
ENSPCOP00000013979Uncharacterized protein. (488 aa)
TRIM62Tripartite motif containing 62. (475 aa)
CTNNB1Catenin beta 1. (781 aa)
ENSPCOP00000000026GOLD domain-containing protein. (157 aa)
CCL21C-C motif chemokine ligand 21. (131 aa)
ENSPCOP00000000471Uncharacterized protein. (96 aa)
TRIM8Tripartite motif containing 8. (551 aa)
TRAF6TNF receptor-associated factor. (498 aa)
LITAFLipopolysaccharide induced TNF factor. (206 aa)
LTBRLymphotoxin beta receptor. (435 aa)
TRIM5Uncharacterized protein. (482 aa)
TRIM32Uncharacterized protein. (653 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (860 aa)
BIRC3Baculoviral IAP repeat containing 3. (597 aa)
TMEM9BTMEM9 domain family member B. (198 aa)
FLNAFilamin A. (2647 aa)
LOC105806826UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (146 aa)
DHX36HA2 domain-containing protein. (718 aa)
DDX50DExD-box helicase 50. (595 aa)
ENSPCOP00000004429TPR_REGION domain-containing protein. (408 aa)
PLEKHG5Pleckstrin homology and RhoGEF domain containing G5. (1085 aa)
TRIML1Tripartite motif family like 1. (468 aa)
TFGTrafficking from ER to golgi regulator. (401 aa)
GOLT1BGolgi transport 1B. (144 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa)
EDAEctodysplasin A; Belongs to the tumor necrosis factor family. (391 aa)
LTFLactotransferrin; Belongs to the transferrin family. (708 aa)
TRIM52Tripartite motif containing 52. (301 aa)
IRF3IRF tryptophan pentad repeat domain-containing protein. (419 aa)
MID2Midline 2. (735 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (553 aa)
TRIM6Tripartite motif containing 6. (510 aa)
RHOARas homolog family member A. (193 aa)
MTDHMetadherin. (580 aa)
BRD4Bromodomain containing 4. (1309 aa)
ENSPCOP00000006977IRF-3 domain-containing protein. (275 aa)
UBDUbiquitin D. (165 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (335 aa)
FYNTyrosine-protein kinase. (537 aa)
CD4CD4 molecule. (452 aa)
EDA2REctodysplasin A2 receptor. (314 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (905 aa)
AJUBAAjuba LIM protein. (539 aa)
RNF31Uncharacterized protein. (1072 aa)
CD74CD74 molecule. (298 aa)
ATP2C1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (915 aa)
CLEC6AC-type lectin domain containing 6A. (158 aa)
TRAF3IP2TRAF3 interacting protein 2. (562 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (365 aa)
S100A12Protein S100; Belongs to the S-100 family. (92 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
CC2D1ACoiled-coil and C2 domain containing 1A. (951 aa)
DHX15DEAH-box helicase 15. (754 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
RHOCRas homolog family member C. (193 aa)
CANT1Calcium activated nucleotidase 1. (401 aa)
NDFIP1Nedd4 family interacting protein 1. (191 aa)
JMJD8Jumonji domain containing 8. (280 aa)
TMED4GOLD domain-containing protein. (227 aa)
TRIM14Tripartite motif containing 14. (447 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (710 aa)
TRIM27Tripartite motif containing 27. (513 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
TMEM101Transmembrane protein 101. (257 aa)
ZDHHC17Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (632 aa)
S100BProtein S100; Belongs to the S-100 family. (92 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
C18orf32Chromosome 18 open reading frame 32. (76 aa)
ABL1Tyrosine-protein kinase. (1146 aa)
CARD9Caspase recruitment domain family member 9. (536 aa)
UNC5CLUnc-5 family C-terminal like. (518 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (949 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (320 aa)
LOC105815151Uncharacterized protein. (913 aa)
TMEM106ATransmembrane protein 106A. (260 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (536 aa)
MALT1MALT1 paracaspase. (787 aa)
DDX1DEAD-box helicase 1. (723 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (205 aa)
TRIML2Tripartite motif family like 2. (437 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
LOC105826437E3 ubiquitin-protein ligase TRIM32. (653 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa)
TNFRSF1ATNF receptor superfamily member 1A. (447 aa)
TERF2IPTERF2 interacting protein. (393 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (490 aa)
LOC105822932Uncharacterized protein. (91 aa)
TFRCTransferrin receptor. (760 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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