23 items (Propithecus coquereli) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Your Input:
	KEL	Kell metallo-endopeptidase (Kell blood group). (730 aa)
	HCRT	Orexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family. (131 aa)
	CAB39	Calcium binding protein 39. (341 aa)
	KCNAB1	Potassium voltage-gated channel subfamily A member regulatory beta subunit 1. (419 aa)
	NOS3	Nitric oxide synthase 3. (994 aa)
	BIN1	Bridging integrator 1. (594 aa)
	KCNRG	Potassium channel regulator. (272 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
	ANK3	Ankyrin 3. (4372 aa)
	KCNE4	Potassium voltage-gated channel subfamily E regulatory subunit 4. (209 aa)
	ENSPCOP00000023835	Uncharacterized protein. (59 aa)
	NOS1	Nitric oxide synthase; Produces nitric oxide (NO). (1434 aa)
	KCNQ1	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (545 aa)
	ATF4	Activating transcription factor 4. (351 aa)
	STK39	Serine/threonine kinase 39. (522 aa)
	PTK2B	Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (967 aa)
	ACTN2	Actinin alpha 2. (874 aa)
	GRP	Gastrin releasing peptide. (137 aa)
	SUMO1	Small ubiquitin-related modifier. (101 aa)
	OXSR1	Oxidative stress responsive kinase 1. (527 aa)
	CRBN	Cereblon. (377 aa)
	KCNH2	Potassium voltage-gated channel subfamily H member 2. (1148 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTN2	CAV1	ENSPCOP00000027671	ENSPCOP00000025045	Actinin alpha 2.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.447
ACTN2	CAV3	ENSPCOP00000027671	ENSPCOP00000004480	Actinin alpha 2.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.512
CAB39	OXSR1	ENSPCOP00000005864	ENSPCOP00000002379	Calcium binding protein 39.	Oxidative stress responsive kinase 1.	0.768
CAB39	STK39	ENSPCOP00000005864	ENSPCOP00000031604	Calcium binding protein 39.	Serine/threonine kinase 39.	0.787
CAV1	ACTN2	ENSPCOP00000025045	ENSPCOP00000027671	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Actinin alpha 2.	0.447
CAV1	CAV3	ENSPCOP00000025045	ENSPCOP00000004480	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.902
CAV1	NOS1	ENSPCOP00000025045	ENSPCOP00000019524	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Nitric oxide synthase; Produces nitric oxide (NO).	0.866
CAV1	NOS3	ENSPCOP00000025045	ENSPCOP00000009840	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Nitric oxide synthase 3.	0.940
CAV3	ACTN2	ENSPCOP00000004480	ENSPCOP00000027671	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Actinin alpha 2.	0.512
CAV3	CAV1	ENSPCOP00000004480	ENSPCOP00000025045	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.902
CAV3	KCNH2	ENSPCOP00000004480	ENSPCOP00000027553	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Potassium voltage-gated channel subfamily H member 2.	0.547
CAV3	KCNQ1	ENSPCOP00000004480	ENSPCOP00000017195	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family.	0.402
CAV3	NOS1	ENSPCOP00000004480	ENSPCOP00000019524	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Nitric oxide synthase; Produces nitric oxide (NO).	0.873
CAV3	NOS3	ENSPCOP00000004480	ENSPCOP00000009840	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Nitric oxide synthase 3.	0.929
GRP	HCRT	ENSPCOP00000000797	ENSPCOP00000006184	Gastrin releasing peptide.	Orexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family.	0.536
HCRT	GRP	ENSPCOP00000006184	ENSPCOP00000000797	Orexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family.	Gastrin releasing peptide.	0.536
KCNAB1	KCNH2	ENSPCOP00000005091	ENSPCOP00000027553	Potassium voltage-gated channel subfamily A member regulatory beta subunit 1.	Potassium voltage-gated channel subfamily H member 2.	0.522
KCNAB1	KCNQ1	ENSPCOP00000005091	ENSPCOP00000017195	Potassium voltage-gated channel subfamily A member regulatory beta subunit 1.	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family.	0.776
KCNE4	KCNH2	ENSPCOP00000023976	ENSPCOP00000027553	Potassium voltage-gated channel subfamily E regulatory subunit 4.	Potassium voltage-gated channel subfamily H member 2.	0.704
KCNE4	KCNQ1	ENSPCOP00000023976	ENSPCOP00000017195	Potassium voltage-gated channel subfamily E regulatory subunit 4.	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family.	0.829