STRINGSTRING
CGN CGN CRB3 CRB3 MXRA8 MXRA8 SHROOM1 SHROOM1 CLDN1 CLDN1 JAM2 JAM2 CTNNA1 CTNNA1 CAMSAP3 CAMSAP3 CGNL1 CGNL1 STRN STRN MAGI2 MAGI2 CCND1 CCND1 ECT2 ECT2 USP53 USP53 DDX58 DDX58 APC APC FRMD4A FRMD4A FRMD4B FRMD4B CYTH2 CYTH2 LOC105826394 LOC105826394 AMOT AMOT NPHP1 NPHP1 CRB2 CRB2 CYTH3 CYTH3 AMOTL1 AMOTL1 WNK3 WNK3 MPDZ MPDZ CLMP CLMP POF1B POF1B MARVELD2 MARVELD2 NECTIN3 NECTIN3 SYMPK SYMPK CTNNB1 CTNNB1 BVES BVES LIN7C LIN7C ENSPCOP00000022199 ENSPCOP00000022199 ENSPCOP00000022056 ENSPCOP00000022056 CLDN15 CLDN15 CLDN7 CLDN7 EPB41L4B EPB41L4B ARHGAP17 ARHGAP17 CTNND1 CTNND1 SHROOM3 SHROOM3 SHROOM4 SHROOM4 ENSPCOP00000020151 ENSPCOP00000020151 RAPGEF2 RAPGEF2 TJP2 TJP2 NECTIN1 NECTIN1 ESAM ESAM JAM3 JAM3 UBN1 UBN1 CDH5 CDH5 TGFBR1 TGFBR1 CYTH1 CYTH1 PLEKHA7 PLEKHA7 NECTIN2 NECTIN2 C1QTNF5 C1QTNF5 JAML JAML CXADR CXADR TJP3 TJP3 ENSPCOP00000016658 ENSPCOP00000016658 OCEL1 OCEL1 ENSPCOP00000016170 ENSPCOP00000016170 CCDC85C CCDC85C PDCD6IP PDCD6IP ADCYAP1R1 ADCYAP1R1 DLG1 DLG1 LIN7B LIN7B DLG3 DLG3 CLDN19 CLDN19 MAGI3 MAGI3 VAPA VAPA PARD3B PARD3B PKN2 PKN2 CLDN10 CLDN10 FRMPD2 FRMPD2 ASH1L ASH1L JUP JUP TJP1 TJP1 PARD3 PARD3 TJAP1 TJAP1 MPP5 MPP5 EPCAM EPCAM MAGI1 MAGI1 PATJ PATJ PMP22 PMP22 NHS NHS ARHGEF2 ARHGEF2 ENSPCOP00000009439 ENSPCOP00000009439 FRMD6 FRMD6 RAP2C RAP2C PLXDC1 PLXDC1 RPGRIP1L RPGRIP1L AOC1 AOC1 ENSPCOP00000008391 ENSPCOP00000008391 CDH1 CDH1 PARD6A PARD6A NPHP4 NPHP4 MTDH MTDH TBCD TBCD VCL VCL SYNPO SYNPO AMOTL2 AMOTL2 PDZD3 PDZD3 VASP VASP ENSPCOP00000005117 ENSPCOP00000005117 LSR LSR ILDR2 ILDR2 RAB13 RAB13 LIN7A LIN7A MARVELD3 MARVELD3 YBX3 YBX3 KIFC3 KIFC3 CLDN9 CLDN9 RAP2B RAP2B OCLN OCLN MPP7 MPP7 SAPCD2 SAPCD2 SORBS1 SORBS1 WNK4 WNK4 F11R F11R CLDN18 CLDN18 LOC105826393 LOC105826393 CDK4 CDK4 PRKCZ PRKCZ TRAF4 TRAF4 CLDN11 CLDN11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CGNCingulin. (1199 aa)
CRB3Crumbs cell polarity complex component 3. (121 aa)
MXRA8Matrix remodeling associated 8. (442 aa)
SHROOM1Shroom family member 1. (829 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
JAM2Junctional adhesion molecule 2. (261 aa)
CTNNA1Catenin alpha 1. (906 aa)
CAMSAP3Calmodulin regulated spectrin associated protein family member 3. (1212 aa)
CGNL1Cingulin like 1. (1256 aa)
STRNStriatin. (657 aa)
MAGI2Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1453 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
ECT2Epithelial cell transforming 2. (598 aa)
USP53Ubiquitin specific peptidase 53. (1092 aa)
DDX58DExD/H-box helicase 58. (688 aa)
APCAPC regulator of WNT signaling pathway. (2844 aa)
FRMD4AFERM domain containing 4A. (1044 aa)
FRMD4BFERM domain containing 4B. (1035 aa)
CYTH2Uncharacterized protein. (407 aa)
LOC105826394Claudin-12. (244 aa)
AMOTAngiomotin. (1083 aa)
NPHP1Nephrocystin 1. (664 aa)
CRB2Crumbs cell polarity complex component 2. (1230 aa)
CYTH3Cytohesin 3. (389 aa)
AMOTL1Angiomotin like 1. (955 aa)
WNK3WNK lysine deficient protein kinase 3. (1791 aa)
MPDZMultiple PDZ domain crumbs cell polarity complex component. (2083 aa)
CLMPCXADR like membrane protein. (377 aa)
POF1BPOF1B actin binding protein. (535 aa)
MARVELD2MARVEL domain containing 2. (492 aa)
NECTIN3Nectin cell adhesion molecule 3. (497 aa)
SYMPKSymplekin. (1307 aa)
CTNNB1Catenin beta 1. (781 aa)
BVESBlood vessel epicardial substance. (360 aa)
LIN7CProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (197 aa)
ENSPCOP00000022199Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (282 aa)
ENSPCOP00000022056PB1 domain-containing protein. (96 aa)
CLDN15Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (228 aa)
CLDN7Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
EPB41L4BErythrocyte membrane protein band 4.1 like 4B. (903 aa)
ARHGAP17Rho GTPase activating protein 17. (883 aa)
CTNND1Catenin delta 1. (984 aa)
SHROOM3Shroom family member 3. (1898 aa)
SHROOM4Shroom family member 4. (1494 aa)
ENSPCOP00000020151EpCAM_N domain-containing protein. (283 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1658 aa)
TJP2Uncharacterized protein; Belongs to the MAGUK family. (1242 aa)
NECTIN1Nectin cell adhesion molecule 1. (516 aa)
ESAMEndothelial cell adhesion molecule. (391 aa)
JAM3Junctional adhesion molecule 3. (310 aa)
UBN1Ubinuclein 1. (1136 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (786 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (421 aa)
CYTH1Cytohesin 1. (363 aa)
PLEKHA7Pleckstrin homology domain containing A7. (1272 aa)
NECTIN2Nectin cell adhesion molecule 2. (537 aa)
C1QTNF5C1q and TNF related 5. (243 aa)
JAMLJunction adhesion molecule like. (335 aa)
CXADRUncharacterized protein. (352 aa)
TJP3Tight junction protein 3; Belongs to the MAGUK family. (922 aa)
ENSPCOP00000016658Uncharacterized protein. (674 aa)
OCEL1Occludin/ELL domain containing 1. (208 aa)
ENSPCOP00000016170Uncharacterized protein. (93 aa)
CCDC85CCoiled-coil domain containing 85C. (418 aa)
PDCD6IPProgrammed cell death 6 interacting protein. (873 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (524 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (910 aa)
LIN7BProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (207 aa)
DLG3Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (849 aa)
CLDN19Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
MAGI3Membrane associated guanylate kinase, WW and PDZ domain containing 3. (1272 aa)
VAPAVAMP associated protein A. (256 aa)
PARD3BPar-3 family cell polarity regulator beta. (978 aa)
PKN2Protein kinase N2. (983 aa)
CLDN10Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (194 aa)
FRMPD2FERM and PDZ domain containing 2. (1309 aa)
ASH1LASH1 like histone lysine methyltransferase. (2964 aa)
JUPJunction plakoglobin. (745 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1768 aa)
PARD3Par-3 family cell polarity regulator. (1296 aa)
TJAP1Tight junction associated protein 1. (559 aa)
MPP5Membrane palmitoylated protein 5; Belongs to the MAGUK family. (627 aa)
EPCAMThyroglobulin type-1 domain-containing protein. (335 aa)
MAGI1Membrane associated guanylate kinase, WW and PDZ domain containing 1. (1453 aa)
PATJPATJ crumbs cell polarity complex component. (1661 aa)
PMP22Peripheral myelin protein 22; Might be involved in growth regulation, and in myelinization in the peripheral nervous system; Belongs to the PMP-22/EMP/MP20 family. (160 aa)
NHSNHS actin remodeling regulator. (1622 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (1013 aa)
ENSPCOP00000009439ASD2 domain-containing protein. (439 aa)
FRMD6FERM domain containing 6. (622 aa)
RAP2CRAP2C, member of RAS oncogene family. (183 aa)
PLXDC1Plexin domain containing 1. (501 aa)
RPGRIP1LRPGRIP1 like. (1172 aa)
AOC1Amine oxidase. (755 aa)
ENSPCOP00000008391PB1 domain-containing protein. (159 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (904 aa)
PARD6APar-6 family cell polarity regulator alpha. (345 aa)
NPHP4Nephrocystin 4. (1427 aa)
MTDHMetadherin. (580 aa)
TBCDTubulin folding cofactor D. (1226 aa)
VCLVinculin. (1134 aa)
SYNPOSynaptopodin. (933 aa)
AMOTL2Angiomotin like 2. (778 aa)
PDZD3PDZ domain containing 3. (544 aa)
VASPVasodilator stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (379 aa)
ENSPCOP00000005117Uncharacterized protein. (338 aa)
LSRLipolysis stimulated lipoprotein receptor. (619 aa)
ILDR2Immunoglobulin like domain containing receptor 2. (639 aa)
RAB13Uncharacterized protein. (202 aa)
LIN7AProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (233 aa)
MARVELD3MARVEL domain containing 3. (342 aa)
YBX3Y-box binding protein 3. (242 aa)
KIFC3Kinesin family member C3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (852 aa)
CLDN9Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)
RAP2BRAP2B, member of RAS oncogene family. (183 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (516 aa)
MPP7Membrane palmitoylated protein 7; Belongs to the MAGUK family. (492 aa)
SAPCD2Suppressor APC domain containing 2. (397 aa)
SORBS1Sorbin and SH3 domain containing 1. (1294 aa)
WNK4WNK lysine deficient protein kinase 4. (1242 aa)
F11RF11 receptor. (296 aa)
CLDN18Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa)
LOC105826393Uncharacterized protein. (244 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
TRAF4TNF receptor-associated factor. (470 aa)
CLDN11Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
Server load: low (26%) [HD]