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| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | ENSPCOP00000010769 | Ig-like domain-containing protein. (119 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa) |
| | TENM1 | Teneurin transmembrane protein 1. (2732 aa) |
| | ERN2 | Endoplasmic reticulum to nucleus signaling 2. (905 aa) |
| | ROR2 | Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (943 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa) |
| | EGF | Epidermal growth factor. (1132 aa) |
| | SYK | Spleen associated tyrosine kinase. (637 aa) |
| | AJUBA | Ajuba LIM protein. (539 aa) |
| | NEK10 | NIMA related kinase 10. (1173 aa) |
| | S100A12 | Protein S100; Belongs to the S-100 family. (92 aa) |
| | RPS3 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | LOC105819920 | Uncharacterized protein. (116 aa) |
| | MAP4K2 | Mitogen-activated protein kinase kinase kinase kinase 2; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (820 aa) |
| | TNFSF11 | TNF superfamily member 11; Belongs to the tumor necrosis factor family. (320 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (394 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1105 aa) |
| | MAP3K10 | Mitogen-activated protein kinase kinase kinase. (959 aa) |
| | TDGF1 | Teratocarcinoma-derived growth factor 1. (186 aa) |
| | CSK | Tyrosine-protein kinase. (450 aa) |
| | HTR2B | 5-hydroxytryptamine receptor 2B. (480 aa) |
| | ERP29 | Endoplasmic reticulum resident protein 29; Does not seem to be a disulfide isomerase. (260 aa) |
| | AXIN1 | Axin 1. (865 aa) |
| | P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa) |
| | FGD2 | FYVE, RhoGEF and PH domain containing 2. (645 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (713 aa) |
| | MAP3K11 | Mitogen-activated protein kinase kinase kinase. (847 aa) |
| | MAP3K12 | Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (891 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1040 aa) |
| | ENSPCOP00000028930 | Uncharacterized protein. (241 aa) |
| | MAP3K13 | Mitogen-activated protein kinase kinase kinase 13. (958 aa) |
| | PDCD10 | Programmed cell death 10. (186 aa) |
| | PDE5A | Phosphodiesterase. (839 aa) |
| | AKAP13 | A-kinase anchoring protein 13. (2786 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1252 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (967 aa) |
| | NTRK3 | Tyrosine-protein kinase receptor. (865 aa) |
| | ENSPCOP00000027398 | KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (281 aa) |
| | DRD4 | Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (333 aa) |
| | CD40 | CD40 molecule. (281 aa) |
| | ELANE | Elastase, neutrophil expressed; Belongs to the peptidase S1 family. (268 aa) |
| | EDN3 | Endothelin 3. (224 aa) |
| | INSR | Insulin receptor. (1192 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (345 aa) |
| | ENSPCOP00000024882 | Ribosomal_S3_C domain-containing protein. (231 aa) |
| | PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa) |
| | THBS1 | Thrombospondin 1. (1185 aa) |
| | LRRK2 | Leucine rich repeat kinase 2. (2427 aa) |
| | FLT3 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (949 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa) |
| | CCL19 | C-C motif chemokine. (108 aa) |
| | KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa) |
| | MIF | Uncharacterized protein. (115 aa) |
| | MST1R | Macrophage stimulating 1 receptor. (1403 aa) |
| | PIK3R5 | Phosphoinositide-3-kinase regulatory subunit 5. (879 aa) |
| | SASH1 | SAM and SH3 domain containing 1. (1248 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | ERN1 | Endoplasmic reticulum to nucleus signaling 1. (935 aa) |
| | TPD52L1 | TPD52 like 1. (209 aa) |
| | ARHGEF5 | Uncharacterized protein. (575 aa) |
| | KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa) |
| | TAOK3 | TAO kinase 3. (898 aa) |
| | NTF3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (270 aa) |
| | ENSPCOP00000021694 | Uncharacterized protein. (146 aa) |
| | DKK1 | Dickkopf WNT signaling pathway inhibitor 1. (268 aa) |
| | ENSPCOP00000020030 | KH type-2 domain-containing protein. (93 aa) |
| | EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa) |
| | ENSPCOP00000019705 | Uncharacterized protein. (583 aa) |
| | DAB2IP | DAB2 interacting protein. (1209 aa) |
| | SRC | Tyrosine-protein kinase. (543 aa) |
| | ADAM8 | ADAM metallopeptidase domain 8. (812 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1210 aa) |
| | MAP2K5 | Mitogen-activated protein kinase kinase 5. (389 aa) |
| | FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa) |
| | DVL3 | Dishevelled segment polarity protein 3. (716 aa) |
| | MAGED1 | MAGE family member D1. (839 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (235 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1317 aa) |
| | PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa) |
| | AGER | Advanced glycosylation end-product specific receptor. (403 aa) |
| | TRAF6 | TNF receptor-associated factor. (498 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (846 aa) |
| | DUSP19 | Dual specificity phosphatase 19. (127 aa) |
| | MAP2K7 | Mitogen-activated protein kinase kinase 7. (435 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) |
| | FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa) |
| | EPGN | Epithelial mitogen. (153 aa) |
| | ROBO1 | Uncharacterized protein. (1334 aa) |
| | ENSPCOP00000006033 | Phospholipase A(2). (94 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (553 aa) |
| | DVL2 | Dishevelled segment polarity protein 2. (736 aa) |
| | ENSPCOP00000006834 | Uncharacterized protein. (78 aa) |
| | EDN1 | Endothelin 1. (193 aa) |
| | TGFA | Transforming growth factor alpha. (190 aa) |
| | PAK1 | Non-specific serine/threonine protein kinase. (544 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | MAP3K4 | Mitogen-activated protein kinase kinase kinase 4. (1598 aa) |
| | TNFRSF11A | TNF receptor superfamily member 11a. (584 aa) |
| | PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (284 aa) |
| | RASGRP1 | RAS guanyl releasing protein 1. (827 aa) |
| | PTPN1 | Tyrosine-protein phosphatase non-receptor type. (435 aa) |
| | FZD8 | Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (406 aa) |
| | MEF2C | Myocyte enhancer factor 2C. (483 aa) |
