54 items (Propithecus coquereli) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SPRY3	Sprouty RTK signaling antagonist 3. (288 aa)
	MAPK8IP1	Mitogen-activated protein kinase 8 interacting protein 1. (711 aa)
	PAQR3	Progestin and adipoQ receptor family member 3. (311 aa)
	SORL1	Sortilin related receptor 1. (2214 aa)
	STK38	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (465 aa)
	DUSP19	Dual specificity phosphatase 19. (127 aa)
	BMP7	Bone morphogenetic protein 7. (431 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	RGS14	Regulator of G protein signaling 14. (567 aa)
	PTPN22	Protein tyrosine phosphatase non-receptor type 22. (653 aa)
	PTPN1	Tyrosine-protein phosphatase non-receptor type. (435 aa)
	APOE	Apolipoprotein E. (314 aa)
	CDK5RAP3	CDK5 regulatory subunit associated protein 3. (505 aa)
	ENSPCOP00000011177	Uncharacterized protein. (295 aa)
	RGS2	Regulator of G protein signaling 2. (211 aa)
	HIPK3	Homeodomain interacting protein kinase 3. (1129 aa)
	PTPRJ	Protein tyrosine phosphatase receptor type J. (1223 aa)
	ADIPOQ	Adiponectin, C1Q and collagen domain containing. (244 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (607 aa)
	AIDA	Uncharacterized protein. (268 aa)
	PIK3CB	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
	ENSPCOP00000016781	Uncharacterized protein. (247 aa)
	CD300A	CD300a molecule. (299 aa)
	SFRP2	Secreted frizzled related protein 2. (295 aa)
	IRAK3	Interleukin 1 receptor associated kinase 3. (505 aa)
	DAB2IP	DAB2 interacting protein. (1209 aa)
	CBLC	Cbl proto-oncogene C. (458 aa)
	DEFB114	Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (70 aa)
	LAX1	Lymphocyte transmembrane adaptor 1. (426 aa)
	DUSP16	Uncharacterized protein. (335 aa)
	SPRY4	Sprouty RTK signaling antagonist 4. (337 aa)
	SMPD1	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (627 aa)
	HYAL2	Hyaluronidase. (473 aa)
	LYN	Tyrosine-protein kinase. (512 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
	DNAJA1	DnaJ heat shock protein family (Hsp40) member A1. (397 aa)
	GSTP1	Glutathione S-transferase pi 1; Belongs to the GST superfamily. (210 aa)
	DUSP10	Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa)
	TMEM130	Transmembrane protein 130. (423 aa)
	NF1	Neurofibromin 1. (2841 aa)
	SPRY1	Sprouty RTK signaling antagonist 1. (319 aa)
	PRKCD	Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
	DUSP1	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
	SPRY2	Sprouty RTK signaling antagonist 2. (314 aa)
	DUSP7	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (420 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	SH2B3	SH2B adaptor protein 3. (539 aa)
	AGT	Angiotensinogen; Belongs to the serpin family. (484 aa)
	LOC105823578	Uncharacterized protein. (375 aa)
	SFRP1	Secreted frizzled related protein 1. (314 aa)
	BMP2	Bone morphogenetic protein 2. (395 aa)
	NPPA	Natriuretic peptide A. (153 aa)
	ENSPCOP00000031075	CR-type domain-containing protein. (300 aa)
	INPP5K	Inositol polyphosphate-5-phosphatase K. (447 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADIPOQ	APOE	ENSPCOP00000013168	ENSPCOP00000010240	Adiponectin, C1Q and collagen domain containing.	Apolipoprotein E.	0.418
ADIPOQ	PAQR3	ENSPCOP00000013168	ENSPCOP00000001572	Adiponectin, C1Q and collagen domain containing.	Progestin and adipoQ receptor family member 3.	0.906
AGT	APOE	ENSPCOP00000029301	ENSPCOP00000010240	Angiotensinogen; Belongs to the serpin family.	Apolipoprotein E.	0.465
AGT	NPPA	ENSPCOP00000029301	ENSPCOP00000030999	Angiotensinogen; Belongs to the serpin family.	Natriuretic peptide A.	0.570
APOE	ADIPOQ	ENSPCOP00000010240	ENSPCOP00000013168	Apolipoprotein E.	Adiponectin, C1Q and collagen domain containing.	0.418
APOE	AGT	ENSPCOP00000010240	ENSPCOP00000029301	Apolipoprotein E.	Angiotensinogen; Belongs to the serpin family.	0.465
APOE	CAV1	ENSPCOP00000010240	ENSPCOP00000025045	Apolipoprotein E.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.414
APOE	SORL1	ENSPCOP00000010240	ENSPCOP00000002469	Apolipoprotein E.	Sortilin related receptor 1.	0.888
BMP2	BMP4	ENSPCOP00000030823	ENSPCOP00000028335	Bone morphogenetic protein 2.	Bone morphogenetic protein 4.	0.896
BMP2	BMP7	ENSPCOP00000030823	ENSPCOP00000003744	Bone morphogenetic protein 2.	Bone morphogenetic protein 7.	0.909
BMP4	BMP2	ENSPCOP00000028335	ENSPCOP00000030823	Bone morphogenetic protein 4.	Bone morphogenetic protein 2.	0.896
BMP4	BMP7	ENSPCOP00000028335	ENSPCOP00000003744	Bone morphogenetic protein 4.	Bone morphogenetic protein 7.	0.906
BMP4	SPRY2	ENSPCOP00000028335	ENSPCOP00000027194	Bone morphogenetic protein 4.	Sprouty RTK signaling antagonist 2.	0.414
BMP7	BMP2	ENSPCOP00000003744	ENSPCOP00000030823	Bone morphogenetic protein 7.	Bone morphogenetic protein 2.	0.909
BMP7	BMP4	ENSPCOP00000003744	ENSPCOP00000028335	Bone morphogenetic protein 7.	Bone morphogenetic protein 4.	0.906
BMP7	SPRY2	ENSPCOP00000003744	ENSPCOP00000027194	Bone morphogenetic protein 7.	Sprouty RTK signaling antagonist 2.	0.612
CAV1	APOE	ENSPCOP00000025045	ENSPCOP00000010240	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Apolipoprotein E.	0.414
CAV1	CAV3	ENSPCOP00000025045	ENSPCOP00000004480	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.902
CAV1	LYN	ENSPCOP00000025045	ENSPCOP00000024889	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Tyrosine-protein kinase.	0.811
CAV1	PIK3CB	ENSPCOP00000025045	ENSPCOP00000016466	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.401