STRINGSTRING
RPS6KB1 RPS6KB1 HAND2 HAND2 GATA5 GATA5 P2RX4 P2RX4 MTPN MTPN PDE9A PDE9A MYOG MYOG CTDP1 CTDP1 NR4A3 NR4A3 CAV3 CAV3 NOTCH1 NOTCH1 TOMM70 TOMM70 AKAP6 AKAP6 PPP3CA PPP3CA CASQ1 CASQ1 SCN5A SCN5A TRIM63 TRIM63 BMP10 BMP10 EDN1 EDN1 JARID2 JARID2 CAMK2B CAMK2B ROCK1 ROCK1 ENSPCOP00000009588 ENSPCOP00000009588 NOS3 NOS3 MYMK MYMK PARP1 PARP1 FOXP1 FOXP1 ACTN3 ACTN3 ROCK2 ROCK2 MLIP MLIP PPARA PPARA RGS2 RGS2 GTF2IRD1 GTF2IRD1 FOXO1 FOXO1 PI16 PI16 GSK3A GSK3A TNFRSF1B TNFRSF1B SGCA SGCA TNNC1 TNNC1 IGFBP5 IGFBP5 ADRA1A ADRA1A SLC9A1 SLC9A1 G6PD G6PD NOL3 NOL3 LMNA LMNA TNNI1 TNNI1 PRKCA PRKCA PDE5A PDE5A TNFRSF1A TNFRSF1A ENSPCOP00000027120 ENSPCOP00000027120 RUSC1 RUSC1 ENSPCOP00000026251 ENSPCOP00000026251 CMYA5 CMYA5 SMAD4 SMAD4 PARP2 PARP2 ENSPCOP00000024369 ENSPCOP00000024369 LMCD1 LMCD1 CDK9 CDK9 DAG1 DAG1 HDAC4 HDAC4 SMAD3 SMAD3 CAMK2D CAMK2D MEF2A MEF2A TRPC3 TRPC3 IGF1 IGF1 ENSPCOP00000018550 ENSPCOP00000018550 PRKAG3 PRKAG3 FBXO32 FBXO32 ERRFI1 ERRFI1 ATP2A2 ATP2A2 SELENON SELENON ENSPCOP00000014148 ENSPCOP00000014148 ATP2B4 ATP2B4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (502 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
GATA5GATA binding protein 5. (394 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (402 aa)
MTPNMyotrophin. (118 aa)
PDE9APhosphodiesterase. (598 aa)
MYOGMyogenin. (224 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (971 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (645 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
NOTCH1Notch receptor 1. (2420 aa)
TOMM70Translocase of outer mitochondrial membrane 70. (553 aa)
AKAP6A-kinase anchoring protein 6. (2315 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (400 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2017 aa)
TRIM63Tripartite motif containing 63. (354 aa)
BMP10Bone morphogenetic protein 10. (423 aa)
EDN1Endothelin 1. (193 aa)
JARID2Jumonji and AT-rich interaction domain containing 2. (1240 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (665 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1316 aa)
ENSPCOP00000009588Uncharacterized protein. (316 aa)
NOS3Nitric oxide synthase 3. (994 aa)
MYMKMyomaker, myoblast fusion factor. (221 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
FOXP1Forkhead box P1. (693 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (936 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1361 aa)
MLIPMuscular LMNA interacting protein. (800 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
RGS2Regulator of G protein signaling 2. (211 aa)
GTF2IRD1GTF2I repeat domain containing 1. (944 aa)
FOXO1Forkhead box O1. (656 aa)
PI16Peptidase inhibitor 16; Belongs to the CRISP family. (452 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (483 aa)
TNFRSF1BTNF receptor superfamily member 1B. (449 aa)
SGCASarcoglycan alpha. (387 aa)
TNNC1Troponin C1, slow skeletal and cardiac type. (161 aa)
IGFBP5Insulin like growth factor binding protein 5. (272 aa)
ADRA1AAdrenoceptor alpha 1A. (466 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
G6PDGlucose-6-phosphate dehydrogenase. (558 aa)
NOL3Nucleolar protein 3. (204 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (665 aa)
TNNI1Troponin I1, slow skeletal type. (187 aa)
PRKCAUncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (575 aa)
PDE5APhosphodiesterase. (839 aa)
TNFRSF1ATNF receptor superfamily member 1A. (447 aa)
ENSPCOP00000027120Uncharacterized protein. (1243 aa)
RUSC1RUN and SH3 domain containing 1. (903 aa)
ENSPCOP00000026251Glutaredoxin domain-containing protein. (175 aa)
CMYA5Cardiomyopathy associated 5. (3989 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
PARP2Poly [ADP-ribose] polymerase. (581 aa)
ENSPCOP00000024369Uncharacterized protein; Belongs to the intermediate filament family. (156 aa)
LMCD1LIM and cysteine rich domains 1. (365 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
DAG1Dystroglycan 1. (895 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (972 aa)
SMAD3Mothers against decapentaplegic homolog. (443 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (503 aa)
MEF2AMyocyte enhancer factor 2A. (495 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (920 aa)
IGF1Insulin like growth factor 1. (208 aa)
ENSPCOP00000018550Uncharacterized protein. (317 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa)
FBXO32F-box protein 32. (355 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (460 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
SELENONSelenoprotein N. (510 aa)
ENSPCOP00000014148Uncharacterized protein. (733 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1204 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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