STRINGSTRING
PDE4D PDE4D ATP2A3 ATP2A3 HAP1 HAP1 ENSPCOP00000000722 ENSPCOP00000000722 PKP2 PKP2 PHPT1 PHPT1 HTT HTT LRRC52 LRRC52 KCNJ11 KCNJ11 DPP10 DPP10 HERPUD1 HERPUD1 PKD1 PKD1 FLNA FLNA ITPR2 ITPR2 TRPC1 TRPC1 CAV3 CAV3 FGF13 FGF13 KCNAB1 KCNAB1 PACS2 PACS2 AKAP6 AKAP6 USP10 USP10 STAC STAC SCN5A SCN5A ENSPCOP00000006829 ENSPCOP00000006829 TCAF1 TCAF1 CIB1 CIB1 S100A10 S100A10 KCNIP1 KCNIP1 ACTN1 ACTN1 ENSPCOP00000008247 ENSPCOP00000008247 KCNC2 KCNC2 FYN FYN ENSPCOP00000009529 ENSPCOP00000009529 CASR CASR ANK1 ANK1 RYR2 RYR2 FKBP1A FKBP1A ANKRD60 ANKRD60 ACTN3 ACTN3 CBARP CBARP LOC105821139 LOC105821139 SLC8A1 SLC8A1 LRRC55 LRRC55 KCNAB3 KCNAB3 MPP6 MPP6 FHL1 FHL1 PYCARD PYCARD SCN10A SCN10A PRKCSH PRKCSH RIMS3 RIMS3 GOPC GOPC HERPUD2 HERPUD2 SCN1B SCN1B SNTA1 SNTA1 AP2M1 AP2M1 BAG2 BAG2 STX1A STX1A HOMER1 HOMER1 PACS1 PACS1 ENSPCOP00000028035 ENSPCOP00000028035 IQANK1 IQANK1 ACTN2 ACTN2 HRC HRC RIMS1 RIMS1 FXYD1 FXYD1 ENSPCOP00000027102 ENSPCOP00000027102 LRRC26 LRRC26 KCNG4 KCNG4 YWHAH YWHAH KCNB1 KCNB1 CAV1 CAV1 LYN LYN PDE4B PDE4B KCNIP2 KCNIP2 LRRK2 LRRK2 KCNE4 KCNE4 YWHAE YWHAE RANGRF RANGRF TCAF2 TCAF2 KCNAB2 KCNAB2 CTNNB1 CTNNB1 LRRC38 LRRC38 ASPH ASPH CAMK2D CAMK2D CHERP CHERP PPP1R9B PPP1R9B SCN4B SCN4B AKAP9 AKAP9 VDAC1 VDAC1 NOS1 NOS1 CDH5 CDH5 SRC SRC TCAP TCAP RIMS2 RIMS2 ENSPCOP00000017622 ENSPCOP00000017622 KCNQ1 KCNQ1 BAK1 BAK1 MPP2 MPP2 ANKDD1B ANKDD1B RNF207 RNF207 ANK2 ANK2 NPTN NPTN FKBP1B FKBP1B ANK3 ANK3 PKD2 PKD2 DLG1 DLG1 GRINA GRINA ATP2A2 ATP2A2 FGF12 FGF12 ENSPCOP00000014532 ENSPCOP00000014532 TSPO TSPO CABP4 CABP4 RIMS4 RIMS4 ABCC8 ABCC8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDE4DPhosphodiesterase. (667 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1033 aa)
HAP1Huntingtin associated protein 1. (670 aa)
ENSPCOP00000000722Protein kinase domain-containing protein. (67 aa)
PKP2Plakophilin 2. (838 aa)
PHPT1Phosphohistidine phosphatase 1. (125 aa)
HTTHuntingtin. (3122 aa)
LRRC52Leucine rich repeat containing 52. (315 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (390 aa)
DPP10Dipeptidyl peptidase like 10; Belongs to the peptidase S9B family. (605 aa)
HERPUD1Homocysteine inducible ER protein with ubiquitin like domain 1. (389 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4265 aa)
FLNAFilamin A. (2647 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2702 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (842 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
KCNAB1Potassium voltage-gated channel subfamily A member regulatory beta subunit 1. (419 aa)
PACS2Phosphofurin acidic cluster sorting protein 2. (889 aa)
AKAP6A-kinase anchoring protein 6. (2315 aa)
USP10Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (798 aa)
STACSH3 and cysteine rich domain. (402 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2017 aa)
ENSPCOP00000006829Uncharacterized protein. (252 aa)
TCAF1TRPM8 channel associated factor 1. (919 aa)
CIB1Calcium and integrin binding 1. (191 aa)
S100A10S_100 domain-containing protein; Belongs to the S-100 family. (97 aa)
KCNIP1Potassium voltage-gated channel interacting protein 1. (232 aa)
ACTN1Actinin alpha 1. (924 aa)
ENSPCOP00000008247Uncharacterized protein. (164 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (638 aa)
FYNTyrosine-protein kinase. (537 aa)
ENSPCOP00000009529Asp-B-Hydro_N domain-containing protein. (270 aa)
CASRCalcium sensing receptor. (1076 aa)
ANK1Ankyrin 1. (1859 aa)
RYR2Ryanodine receptor 2. (4825 aa)
FKBP1APeptidylprolyl isomerase. (108 aa)
ANKRD60Ankyrin repeat domain 60. (339 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (936 aa)
CBARPUncharacterized protein. (716 aa)
LOC105821139Aldo_ket_red domain-containing protein. (364 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (974 aa)
LRRC55Leucine rich repeat containing 55. (311 aa)
KCNAB3Potassium voltage-gated channel subfamily A regulatory beta subunit 3. (398 aa)
MPP6Membrane palmitoylated protein 6; Belongs to the MAGUK family. (573 aa)
FHL1Four and a half LIM domains 1. (323 aa)
PYCARDPYD and CARD domain containing. (195 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1958 aa)
PRKCSHProtein kinase C substrate 80K-H. (491 aa)
RIMS3Regulating synaptic membrane exocytosis 3. (308 aa)
GOPCPDZ domain-containing protein. (463 aa)
HERPUD2HERPUD family member 2. (405 aa)
SCN1BSodium voltage-gated channel beta subunit 1. (218 aa)
SNTA1Syntrophin alpha 1. (505 aa)
AP2M1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (452 aa)
BAG2BCL2 associated athanogene 2. (211 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (288 aa)
HOMER1Homer scaffold protein 1. (329 aa)
PACS1Phosphofurin acidic cluster sorting protein 1. (865 aa)
ENSPCOP00000028035Peptidylprolyl isomerase. (96 aa)
IQANK1IQ motif and ankyrin repeat containing 1. (564 aa)
ACTN2Actinin alpha 2. (874 aa)
HRCHistidine rich calcium binding protein. (688 aa)
RIMS1Regulating synaptic membrane exocytosis 1. (1692 aa)
FXYD1FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (92 aa)
ENSPCOP00000027102Peptidylprolyl isomerase. (88 aa)
LRRC26Leucine rich repeat containing 26. (335 aa)
KCNG4Potassium voltage-gated channel modifier subfamily G member 4; Belongs to the potassium channel family. (517 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (246 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
LYNTyrosine-protein kinase. (512 aa)
PDE4BPhosphodiesterase. (567 aa)
KCNIP2Potassium voltage-gated channel interacting protein 2. (285 aa)
LRRK2Leucine rich repeat kinase 2. (2427 aa)
KCNE4Potassium voltage-gated channel subfamily E regulatory subunit 4. (209 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa)
RANGRFRAN guanine nucleotide release factor. (186 aa)
TCAF2Peptidase M60 domain-containing protein. (726 aa)
KCNAB2Aldo_ket_red domain-containing protein. (243 aa)
CTNNB1Catenin beta 1. (781 aa)
LRRC38Leucine rich repeat containing 38. (295 aa)
ASPHAspartate beta-hydroxylase. (687 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (503 aa)
CHERPCalcium homeostasis endoplasmic reticulum protein. (606 aa)
PPP1R9BProtein phosphatase 1 regulatory subunit 9B. (819 aa)
SCN4BSodium voltage-gated channel beta subunit 4. (225 aa)
AKAP9A-kinase anchoring protein 9. (3687 aa)
VDAC1Uncharacterized protein. (283 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1434 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (786 aa)
SRCTyrosine-protein kinase. (543 aa)
TCAPTitin-cap. (167 aa)
RIMS2Regulating synaptic membrane exocytosis 2. (1081 aa)
ENSPCOP00000017622Uncharacterized protein. (122 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (545 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
MPP2Membrane palmitoylated protein 2; Belongs to the MAGUK family. (584 aa)
ANKDD1BAnkyrin repeat and death domain containing 1B. (528 aa)
RNF207Ring finger protein 207. (634 aa)
ANK2Ankyrin 2. (3925 aa)
NPTNUncharacterized protein. (399 aa)
FKBP1BPeptidylprolyl isomerase. (119 aa)
ANK3Ankyrin 3. (4372 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (963 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (910 aa)
GRINAGlutamate ionotropic receptor NMDA type subunit associated protein 1. (371 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
FGF12Fibroblast growth factor 12; Belongs to the heparin-binding growth factors family. (208 aa)
ENSPCOP00000014532S_100 domain-containing protein; Belongs to the S-100 family. (88 aa)
TSPOTranslocator protein. (169 aa)
CABP4Calcium binding protein 4. (278 aa)
RIMS4Regulating synaptic membrane exocytosis 4. (277 aa)
ABCC8ATP binding cassette subfamily C member 8. (1582 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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