STRINGSTRING
FLOT2 FLOT2 CORO1C CORO1C DAG1 DAG1 LRRK2 LRRK2 TEX101 TEX101 CAV1 CAV1 KCNMA1 KCNMA1 PACSIN2 PACSIN2 STIM1 STIM1 ADRA1A ADRA1A PRKAR2A PRKAR2A LRP4 LRP4 CTNNA1 CTNNA1 GASK1A GASK1A EFNA5 EFNA5 PLPP2 PLPP2 HDAC6 HDAC6 ADD2 ADD2 SPRED1 SPRED1 FXYD1 FXYD1 CAV2 CAV2 CDH15 CDH15 INSR INSR LRP8 LRP8 MAPK1 MAPK1 FLOT1 FLOT1 AKAP6 AKAP6 HTR2A HTR2A SLC6A3 SLC6A3 CAVIN2 CAVIN2 SCARB1 SCARB1 SCN5A SCN5A NEU3 NEU3 CDH2 CDH2 ITGB2 ITGB2 CD8A CD8A SELE SELE MYO1A MYO1A PLPP1 PLPP1 MAPK3 MAPK3 CDH1 CDH1 AQP1 AQP1 PTGS2 PTGS2 DLC1 DLC1 NOS1AP NOS1AP NOS3 NOS3 CLN3 CLN3 CD36 CD36 ADRA1B ADRA1B TRPC4 TRPC4 CBL CBL HCK HCK ADCY8 ADCY8 TREM2 TREM2 ENSPCOP00000014061 ENSPCOP00000014061 ATP2B4 ATP2B4 MLC1 MLC1 ENSPCOP00000014320 ENSPCOP00000014320 HAS2 HAS2 ADCYAP1R1 ADCYAP1R1 CHRNB2 CHRNB2 CAVIN1 CAVIN1 SRC SRC MAL MAL KIF18A KIF18A SKAP1 SKAP1 LYPD4 LYPD4 LCP2 LCP2 IGF1R IGF1R PTGIS PTGIS ORAI1 ORAI1 PTCH1 PTCH1 BVES BVES CTNNB1 CTNNB1 LIPE LIPE RANGRF RANGRF SLC2A1 SLC2A1 SORBS1 SORBS1 ADTRP ADTRP EHD2 EHD2 CAVIN3 CAVIN3 SELPLG SELPLG CAVIN4 CAVIN4 CAV3 CAV3 CHRNA3 CHRNA3 SMPD2 SMPD2 EZR EZR TGFBR2 TGFBR2 CD177 CD177 MYOF MYOF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (525 aa)
DAG1Dystroglycan 1. (895 aa)
LRRK2Leucine rich repeat kinase 2. (2427 aa)
TEX101Testis expressed 101. (262 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1286 aa)
PACSIN2Protein kinase C and casein kinase substrate in neurons 2. (486 aa)
STIM1Stromal interaction molecule 1. (784 aa)
ADRA1AAdrenoceptor alpha 1A. (466 aa)
PRKAR2AProtein kinase cAMP-dependent type II regulatory subunit alpha. (399 aa)
LRP4LDL receptor related protein 4. (1922 aa)
CTNNA1Catenin alpha 1. (906 aa)
GASK1AGolgi associated kinase 1A. (577 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (228 aa)
PLPP2Phospholipid phosphatase 2. (304 aa)
HDAC6Histone deacetylase 6. (1203 aa)
ADD2Adducin 2. (725 aa)
SPRED1Sprouty related EVH1 domain containing 1. (444 aa)
FXYD1FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (92 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
CDH15Cadherin 15; Cadherins are calcium-dependent cell adhesion proteins. (785 aa)
INSRInsulin receptor. (1192 aa)
LRP8LDL receptor related protein 8. (956 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
AKAP6A-kinase anchoring protein 6. (2315 aa)
HTR2A5-hydroxytryptamine receptor 2A. (471 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (619 aa)
CAVIN2Uncharacterized protein. (424 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (461 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2017 aa)
NEU3Neuraminidase 3. (462 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
ITGB2Integrin beta. (764 aa)
CD8ACD8a molecule. (239 aa)
SELESelectin E. (610 aa)
MYO1AMyosin IA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1043 aa)
PLPP1Phospholipid phosphatase 1. (286 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (904 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
DLC1DLC1 Rho GTPase activating protein. (1125 aa)
NOS1APNitric oxide synthase 1 adaptor protein. (507 aa)
NOS3Nitric oxide synthase 3. (994 aa)
CLN3Battenin. (438 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
ADRA1BAdrenoceptor alpha 1B. (518 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (982 aa)
CBLCbl proto-oncogene. (891 aa)
HCKTyrosine-protein kinase. (524 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1229 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (224 aa)
ENSPCOP00000014061Peptidase S1 domain-containing protein. (113 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1204 aa)
MLC1Modulator of VRAC current 1. (378 aa)
ENSPCOP00000014320Uncharacterized protein. (415 aa)
HAS2Hyaluronan synthase 2. (552 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (524 aa)
CHRNB2Cholinergic receptor nicotinic beta 2 subunit. (502 aa)
CAVIN1Caveolae associated protein 1. (389 aa)
SRCTyrosine-protein kinase. (543 aa)
MALMal, T cell differentiation protein. (153 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (843 aa)
SKAP1Src kinase associated phosphoprotein 1. (358 aa)
LYPD4LY6/PLAUR domain containing 4. (246 aa)
LCP2Lymphocyte cytosolic protein 2. (493 aa)
IGF1RTyrosine-protein kinase receptor. (1350 aa)
PTGISProstacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (307 aa)
PTCH1Patched 1. (1449 aa)
BVESBlood vessel epicardial substance. (360 aa)
CTNNB1Catenin beta 1. (781 aa)
LIPELipase E, hormone sensitive type. (1052 aa)
RANGRFRAN guanine nucleotide release factor. (186 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (495 aa)
SORBS1Sorbin and SH3 domain containing 1. (1294 aa)
ADTRPAndrogen dependent TFPI regulating protein. (237 aa)
EHD2EH domain containing 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (543 aa)
CAVIN3Caveolae associated protein 3. (286 aa)
SELPLGUncharacterized protein. (386 aa)
CAVIN4Caveolae associated protein 4. (364 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
CHRNA3Cholinergic receptor nicotinic alpha 3 subunit. (500 aa)
SMPD2Sphingomyelin phosphodiesterase 2. (423 aa)
EZREzrin. (586 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
CD177CD177 molecule. (439 aa)
MYOFMyoferlin. (2061 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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