STRINGSTRING
CLDN19 CLDN19 MTSS1 MTSS1 CDH8 CDH8 CLDN1 CLDN1 TRPV4 TRPV4 CTNNA1 CTNNA1 CAMSAP3 CAMSAP3 CSK CSK PTPRO PTPRO LIMS1 LIMS1 STRN STRN PKP4 PKP4 PRKCA PRKCA ECT2 ECT2 APC APC NLGN2 NLGN2 GJA1 GJA1 HIPK1 HIPK1 PKHD1 PKHD1 TLNRD1 TLNRD1 TLN1 TLN1 CSF1R CSF1R AMOT AMOT WDR1 WDR1 ENSPCOP00000025645 ENSPCOP00000025645 POF1B POF1B ZNF703 ZNF703 MARVELD2 MARVELD2 FLCN FLCN TGFB1 TGFB1 FBF1 FBF1 CTNNB1 CTNNB1 NPHS1 NPHS1 DSG2 DSG2 PLEC PLEC ENSPCOP00000022056 ENSPCOP00000022056 CLDN15 CLDN15 CLDN7 CLDN7 SMAD3 SMAD3 HEG1 HEG1 PERP PERP INAVA INAVA PAK2 PAK2 CTNND1 CTNND1 ADAM10 ADAM10 SRF SRF NECTIN1 NECTIN1 CDH20 CDH20 JAM3 JAM3 PIP5K1C PIP5K1C EXT1 EXT1 NUMBL NUMBL RAMP2 RAMP2 ARVCF ARVCF GNPAT GNPAT CDH5 CDH5 WHRN WHRN SRC SRC ARL2 ARL2 TLN2 TLN2 CDHR3 CDHR3 CDH11 CDH11 PLEKHA7 PLEKHA7 UGT8 UGT8 CXADR CXADR TJP3 TJP3 ANK2 ANK2 OCEL1 OCEL1 ENSPCOP00000016170 ENSPCOP00000016170 PDCD6IP PDCD6IP NUMB NUMB DLG1 DLG1 FER FER ENSPCOP00000014061 ENSPCOP00000014061 PKN2 PKN2 NR1H4 NR1H4 CD9 CD9 FRMPD2 FRMPD2 JUP JUP ENSPCOP00000012261 ENSPCOP00000012261 LIM2 LIM2 TJP1 TJP1 FERMT2 FERMT2 PARD3 PARD3 DSG1 DSG1 NF2 NF2 CCM2 CCM2 RHOC RHOC CDH18 CDH18 CDH7 CDH7 PATJ PATJ PMP22 PMP22 ENSPCOP00000009889 ENSPCOP00000009889 MPZ MPZ ENSPCOP00000009588 ENSPCOP00000009588 CDH22 CDH22 CTNND2 CTNND2 PKP1 PKP1 SNAI2 SNAI2 CDH1 CDH1 DSP DSP PARD6A PARD6A PKP3 PKP3 FSCN1 FSCN1 CDH9 CDH9 TGFB3 TGFB3 TBCD TBCD CDH2 CDH2 RHOA RHOA VCL VCL WNT11 WNT11 GJB6 GJB6 CDH10 CDH10 PRKCI PRKCI LSR LSR GJB2 GJB2 AFDN AFDN RAB13 RAB13 XIRP2 XIRP2 MARVELD3 MARVELD3 SVEP1 SVEP1 KIFC3 KIFC3 KIRREL1 KIRREL1 FLNA FLNA CLDN9 CLDN9 CDH6 CDH6 OCLN OCLN MPP7 MPP7 GJB1 GJB1 PECAM1 PECAM1 CNTNAP1 CNTNAP1 EPB41L3 EPB41L3 HDAC7 HDAC7 GJC1 GJC1 CLDN18 CLDN18 LIMS2 LIMS2 CD177 CD177 TGFB2 TGFB2 PKP2 PKP2 GRHL2 GRHL2 SMAD7 SMAD7 CDH24 CDH24 CLDN11 CLDN11 EPHB2 EPHB2 CDH19 CDH19 EFNB2 EFNB2 DLG5 DLG5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CLDN19Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
MTSS1MTSS I-BAR domain containing 1. (759 aa)
CDH8Cadherin 8; Cadherins are calcium-dependent cell adhesion proteins. (752 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (870 aa)
CTNNA1Catenin alpha 1. (906 aa)
CAMSAP3Calmodulin regulated spectrin associated protein family member 3. (1212 aa)
CSKTyrosine-protein kinase. (450 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1031 aa)
LIMS1LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (398 aa)
STRNStriatin. (657 aa)
PKP4Plakophilin 4. (1192 aa)
PRKCAUncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (575 aa)
ECT2Epithelial cell transforming 2. (598 aa)
APCAPC regulator of WNT signaling pathway. (2844 aa)
NLGN2Neuroligin 2. (835 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
HIPK1Homeodomain interacting protein kinase 1. (1131 aa)
PKHD1PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (3878 aa)
TLNRD1Talin rod domain containing 1. (364 aa)
TLN1Talin 1. (2548 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (964 aa)
AMOTAngiomotin. (1083 aa)
WDR1WD repeat domain 1. (606 aa)
ENSPCOP00000025645Uncharacterized protein. (162 aa)
POF1BPOF1B actin binding protein. (535 aa)
ZNF703Zinc finger protein 703. (589 aa)
MARVELD2MARVEL domain containing 2. (492 aa)
FLCNFolliculin. (579 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
FBF1Fas binding factor 1. (1140 aa)
CTNNB1Catenin beta 1. (781 aa)
NPHS1NPHS1 adhesion molecule, nephrin. (1238 aa)
DSG2Desmoglein 2. (1029 aa)
PLECPlectin. (4689 aa)
ENSPCOP00000022056PB1 domain-containing protein. (96 aa)
CLDN15Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (228 aa)
CLDN7Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
SMAD3Mothers against decapentaplegic homolog. (443 aa)
HEG1Heart development protein with EGF like domains 1. (1372 aa)
PERPP53 apoptosis effector related to PMP22. (193 aa)
INAVAInnate immunity activator. (662 aa)
PAK2Non-specific serine/threonine protein kinase. (492 aa)
CTNND1Catenin delta 1. (984 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
SRFSerum response factor. (508 aa)
NECTIN1Nectin cell adhesion molecule 1. (516 aa)
CDH20Cadherin 20; Cadherins are calcium-dependent cell adhesion proteins. (786 aa)
JAM3Junctional adhesion molecule 3. (310 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (682 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
NUMBLNUMB like endocytic adaptor protein. (592 aa)
RAMP2Receptor activity modifying protein 2. (179 aa)
ARVCFARVCF delta catenin family member. (965 aa)
GNPATDihydroxyacetone phosphate acyltransferase. (680 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (786 aa)
WHRNWhirlin. (905 aa)
SRCTyrosine-protein kinase. (543 aa)
ARL2ADP ribosylation factor like GTPase 2; Belongs to the small GTPase superfamily. Arf family. (184 aa)
TLN2Talin 2. (2542 aa)
CDHR3Cadherin related family member 3. (884 aa)
CDH11Cadherin 11; Cadherins are calcium-dependent cell adhesion proteins. (796 aa)
PLEKHA7Pleckstrin homology domain containing A7. (1272 aa)
UGT8UDP glycosyltransferase 8. (474 aa)
CXADRUncharacterized protein. (352 aa)
TJP3Tight junction protein 3; Belongs to the MAGUK family. (922 aa)
ANK2Ankyrin 2. (3925 aa)
OCEL1Occludin/ELL domain containing 1. (208 aa)
ENSPCOP00000016170Uncharacterized protein. (93 aa)
PDCD6IPProgrammed cell death 6 interacting protein. (873 aa)
NUMBNUMB endocytic adaptor protein. (628 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (910 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
ENSPCOP00000014061Peptidase S1 domain-containing protein. (113 aa)
PKN2Protein kinase N2. (983 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (486 aa)
CD9Tetraspanin. (228 aa)
FRMPD2FERM and PDZ domain containing 2. (1309 aa)
JUPJunction plakoglobin. (745 aa)
ENSPCOP00000012261Uncharacterized protein. (74 aa)
LIM2Lens fiber membrane intrinsic protein; Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis; Belongs to the PMP-22/EMP/MP20 family. (173 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1768 aa)
FERMT2Fermitin family member 2. (693 aa)
PARD3Par-3 family cell polarity regulator. (1296 aa)
DSG1Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1043 aa)
NF2Neurofibromin 2. (596 aa)
CCM2CCM2 scaffold protein. (467 aa)
RHOCRas homolog family member C. (193 aa)
CDH18Cadherin 18; Cadherins are calcium-dependent cell adhesion proteins. (719 aa)
CDH7Cadherin 7; Cadherins are calcium-dependent cell adhesion proteins. (660 aa)
PATJPATJ crumbs cell polarity complex component. (1661 aa)
PMP22Peripheral myelin protein 22; Might be involved in growth regulation, and in myelinization in the peripheral nervous system; Belongs to the PMP-22/EMP/MP20 family. (160 aa)
ENSPCOP00000009889Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (543 aa)
MPZMyelin protein zero. (248 aa)
ENSPCOP00000009588Uncharacterized protein. (316 aa)
CDH22Cadherin 22; Cadherins are calcium-dependent cell adhesion proteins. (834 aa)
CTNND2Catenin delta 2. (1181 aa)
PKP1Plakophilin 1. (746 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (904 aa)
DSPDesmoplakin. (2868 aa)
PARD6APar-6 family cell polarity regulator alpha. (345 aa)
PKP3Plakophilin 3. (796 aa)
FSCN1Fascin. (493 aa)
CDH9Cadherin 9; Cadherins are calcium-dependent cell adhesion proteins. (456 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
TBCDTubulin folding cofactor D. (1226 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
RHOARas homolog family member A. (193 aa)
VCLVinculin. (1134 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
GJB6Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (261 aa)
CDH10Cadherin 10; Cadherins are calcium-dependent cell adhesion proteins. (446 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (522 aa)
LSRLipolysis stimulated lipoprotein receptor. (619 aa)
GJB2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (226 aa)
AFDNAfadin, adherens junction formation factor. (1771 aa)
RAB13Uncharacterized protein. (202 aa)
XIRP2Xin actin binding repeat containing 2. (3545 aa)
MARVELD3MARVEL domain containing 3. (342 aa)
SVEP1Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1. (3230 aa)
KIFC3Kinesin family member C3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (852 aa)
KIRREL1Kirre like nephrin family adhesion molecule 1. (757 aa)
FLNAFilamin A. (2647 aa)
CLDN9Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)
CDH6Cadherin 6; Cadherins are calcium-dependent cell adhesion proteins. (699 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (516 aa)
MPP7Membrane palmitoylated protein 7; Belongs to the MAGUK family. (492 aa)
GJB1Gap junction protein beta 1. (183 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (698 aa)
CNTNAP1Contactin associated protein 1. (1382 aa)
EPB41L3Erythrocyte membrane protein band 4.1 like 3. (1096 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (991 aa)
GJC1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (396 aa)
CLDN18Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa)
LIMS2LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (366 aa)
CD177CD177 molecule. (439 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
PKP2Plakophilin 2. (838 aa)
GRHL2Grainyhead like transcription factor 2. (625 aa)
SMAD7Mothers against decapentaplegic homolog. (490 aa)
CDH24Cadherin 24; Cadherins are calcium-dependent cell adhesion proteins. (822 aa)
CLDN11Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa)
EPHB2EPH receptor B2. (1039 aa)
CDH19CA domain-containing protein; Cadherins are calcium-dependent cell adhesion proteins. (390 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (335 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1919 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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