STRINGSTRING
CTSS CTSS LOC105824222 LOC105824222 APPL1 APPL1 SYK SYK HGS HGS LOC105807649 LOC105807649 APPL2 APPL2 CD36 CD36 ITGAV ITGAV SYT11 SYT11 OCRL OCRL CLEC4E CLEC4E RAB14 RAB14 TRIM14 TRIM14 RAB32 RAB32 TAPBP TAPBP TLR1 TLR1 ATP6V0B ATP6V0B ENSPCOP00000013454 ENSPCOP00000013454 SCIMP SCIMP NCF4 NCF4 RAB39A RAB39A LOC105817910 LOC105817910 RAB8B RAB8B RAB22A RAB22A RAB7B RAB7B MPO MPO PLD4 PLD4 VIM VIM MYO1C MYO1C GSN GSN PIP4P1 PIP4P1 SLC11A1 SLC11A1 SNX3 SNX3 UVRAG UVRAG RAB38 RAB38 ENSPCOP00000008058 ENSPCOP00000008058 STX6 STX6 CORO1A CORO1A ZDHHC5 ZDHHC5 CYBA CYBA RAB20 RAB20 LOC105817846 LOC105817846 DNM2 DNM2 ELANE ELANE ATP6V0A2 ATP6V0A2 VAMP8 VAMP8 HVCN1 HVCN1 PIK3C3 PIK3C3 INPP5B INPP5B RAB10 RAB10 LOC105812575 LOC105812575 NOD2 NOD2 LOC105817290 LOC105817290 SYT7 SYT7 TCIRG1 TCIRG1 SRGAP2 SRGAP2 RILP RILP RAB11B RAB11B AMBRA1 AMBRA1 RAB23 RAB23 NOD1 NOD1 ATG14 ATG14 VPS26B VPS26B PLA2G5 PLA2G5 WAS WAS FLNB FLNB PIP4P2 PIP4P2 ATP6V0C ATP6V0C RAB9B RAB9B LOC105817288 LOC105817288 STXBP3 STXBP3 MTOR MTOR CYBB CYBB ENSPCOP00000002211 ENSPCOP00000002211 ENSPCOP00000002833 ENSPCOP00000002833 ANXA11 ANXA11 LAMP2 LAMP2 ENSPCOP00000003740 ENSPCOP00000003740 FMNL1 FMNL1 VAMP7 VAMP7 STX4 STX4 ITGB5 ITGB5 RAB5A RAB5A RAB7A RAB7A ZYX ZYX LTF LTF KIF5B KIF5B TLR9 TLR9 STX12 STX12 ABCA1 ABCA1 NCF1 NCF1 ENSPCOP00000007709 ENSPCOP00000007709 RAB43 RAB43 ENSPCOP00000008371 ENSPCOP00000008371 RAB11FIP1 RAB11FIP1 ADAM8 ADAM8 RAB34 RAB34 RAB11FIP5 RAB11FIP5 MCOLN1 MCOLN1 SNAP23 SNAP23 PIKFYVE PIKFYVE ENSPCOP00000020006 ENSPCOP00000020006 SLAMF1 SLAMF1 ATP6V0A4 ATP6V0A4 LAMP1 LAMP1 ENSPCOP00000021197 ENSPCOP00000021197 RAB31 RAB31 UNC93B1 UNC93B1 ATP7A ATP7A RAB8A RAB8A STXBP4 STXBP4 STX8 STX8 CDC42EP4 CDC42EP4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CTSSCathepsin S; Belongs to the peptidase C1 family. (331 aa)
LOC105824222Uncharacterized protein. (216 aa)
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (661 aa)
SYKSpleen associated tyrosine kinase. (637 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa)
LOC105807649Uncharacterized protein. (209 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (591 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1047 aa)
SYT11Synaptotagmin 11. (431 aa)
OCRLOCRL inositol polyphosphate-5-phosphatase. (894 aa)
CLEC4EC-type lectin domain family 4 member E. (218 aa)
RAB14RAB14, member RAS oncogene family. (215 aa)
TRIM14Tripartite motif containing 14. (447 aa)
RAB32RAB32, member RAS oncogene family. (225 aa)
TAPBPTAP binding protein. (482 aa)
TLR1Toll-like receptor. (774 aa)
ATP6V0BATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family. (291 aa)
ENSPCOP00000013454Ig-like domain-containing protein; Belongs to the MHC class I family. (365 aa)
SCIMPSLP adaptor and CSK interacting membrane protein. (141 aa)
NCF4Neutrophil cytosolic factor 4. (306 aa)
RAB39ARAB39A, member RAS oncogene family. (217 aa)
LOC105817910Ig-like domain-containing protein; Belongs to the MHC class I family. (363 aa)
RAB8BRAB8B, member RAS oncogene family. (207 aa)
RAB22ARAB22A, member RAS oncogene family. (194 aa)
RAB7BRAB7B, member RAS oncogene family. (199 aa)
MPOMyeloperoxidase. (742 aa)
PLD4Phospholipase D family member 4. (502 aa)
VIMVimentin; Belongs to the intermediate filament family. (466 aa)
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1063 aa)
GSNGelsolin. (778 aa)
PIP4P1Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (290 aa)
SLC11A1Solute carrier family 11 member 1. (546 aa)
SNX3Sorting nexin 3. (162 aa)
UVRAGUV radiation resistance associated. (701 aa)
RAB38RAB38, member RAS oncogene family. (211 aa)
ENSPCOP00000008058Uncharacterized protein. (1607 aa)
STX6Syntaxin 6; Belongs to the syntaxin family. (255 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
ZDHHC5Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (715 aa)
CYBACytochrome b-245 alpha chain. (129 aa)
RAB20RAB20, member RAS oncogene family. (234 aa)
LOC105817846Ig-like domain-containing protein; Belongs to the MHC class I family. (373 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
ELANEElastase, neutrophil expressed; Belongs to the peptidase S1 family. (268 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (829 aa)
VAMP8Vesicle associated membrane protein 8. (100 aa)
HVCN1Hydrogen voltage gated channel 1. (271 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (734 aa)
INPP5BInositol polyphosphate-5-phosphatase B. (953 aa)
RAB10RAB10, member RAS oncogene family. (200 aa)
LOC105812575Phospholipase D4-like. (76 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1040 aa)
LOC105817290Ig-like domain-containing protein; Belongs to the MHC class I family. (464 aa)
SYT7Synaptotagmin 7. (686 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
SRGAP2Uncharacterized protein. (1071 aa)
RILPRab interacting lysosomal protein. (403 aa)
RAB11BRAB11B, member RAS oncogene family. (218 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1270 aa)
RAB23RAB23, member RAS oncogene family. (237 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (949 aa)
ATG14Autophagy related 14. (464 aa)
VPS26BVPS26, retromer complex component B. (336 aa)
PLA2G5Phospholipase A(2). (138 aa)
WASWASP actin nucleation promoting factor. (503 aa)
FLNBFilamin B. (2633 aa)
PIP4P2Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (154 aa)
RAB9BRAB9B, member RAS oncogene family. (201 aa)
LOC105817288Ig-like domain-containing protein; Belongs to the MHC class I family. (371 aa)
STXBP3Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (448 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2536 aa)
CYBBCytochrome b-245 beta chain. (533 aa)
ENSPCOP00000002211Ig-like domain-containing protein; Belongs to the MHC class I family. (389 aa)
ENSPCOP00000002833Uncharacterized protein. (145 aa)
ANXA11Annexin. (504 aa)
LAMP2Lysosomal associated membrane protein 2. (414 aa)
ENSPCOP00000003740Uncharacterized protein. (214 aa)
FMNL1Formin like 1. (1107 aa)
VAMP7Vesicle associated membrane protein 7; Belongs to the synaptobrevin family. (220 aa)
STX4Syntaxin 4; Belongs to the syntaxin family. (298 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (802 aa)
RAB5ARAB5A, member RAS oncogene family. (215 aa)
RAB7ARAB7A, member RAS oncogene family. (161 aa)
ZYXZyxin. (570 aa)
LTFLactotransferrin; Belongs to the transferrin family. (708 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (829 aa)
TLR9TIR domain-containing protein. (1029 aa)
STX12Syntaxin 12; Belongs to the syntaxin family. (276 aa)
ABCA1ATP binding cassette subfamily A member 1. (2240 aa)
NCF1Neutrophil cytosolic factor 1. (390 aa)
ENSPCOP00000007709Uncharacterized protein. (186 aa)
RAB43RAB43, member RAS oncogene family. (213 aa)
ENSPCOP00000008371Uncharacterized protein. (101 aa)
RAB11FIP1Uncharacterized protein. (639 aa)
ADAM8ADAM metallopeptidase domain 8. (812 aa)
RAB34RAB34, member RAS oncogene family. (268 aa)
RAB11FIP5Uncharacterized protein. (1323 aa)
MCOLN1Mucolipin 1. (569 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2053 aa)
ENSPCOP00000020006t-SNARE coiled-coil homology domain-containing protein. (172 aa)
SLAMF1Signaling lymphocytic activation molecule family member 1. (368 aa)
ATP6V0A4V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (840 aa)
LAMP1Lysosomal associated membrane protein 1. (384 aa)
ENSPCOP00000021197Synaptosomal-associated protein; Belongs to the SNAP-25 family. (192 aa)
RAB31RAB31, member RAS oncogene family. (195 aa)
UNC93B1Unc-93 homolog B1, TLR signaling regulator. (600 aa)
ATP7AATPase copper transporting alpha. (1502 aa)
RAB8ARAB8A, member RAS oncogene family. (207 aa)
STXBP4Syntaxin binding protein 4. (517 aa)
STX8Syntaxin 8. (236 aa)
CDC42EP4CDC42 effector protein 4. (283 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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