STRINGSTRING
ADIPOQ ADIPOQ G6PD G6PD CSF3 CSF3 CLDN1 CLDN1 RPS6KB1 RPS6KB1 ENSPCOP00000030811 ENSPCOP00000030811 BAD BAD FGFR2 FGFR2 UNC79 UNC79 HMGCS2 HMGCS2 ST6GAL1 ST6GAL1 OGG1 OGG1 EIF4G1 EIF4G1 PTK2B PTK2B CRHBP CRHBP SLC10A1 SLC10A1 DRD4 DRD4 POLB POLB GRIN2B GRIN2B PRKCE PRKCE MAOB MAOB CYP7A1 CYP7A1 RGS19 RGS19 DNMT3A DNMT3A GLRA1 GLRA1 GOT2 GOT2 TH TH ADCY7 ADCY7 GNRH1 GNRH1 SREBF1 SREBF1 NR0B2 NR0B2 RARA RARA CASP8 CASP8 RGS7 RGS7 TYMS TYMS TP53INP1 TP53INP1 DBH DBH CLDN7 CLDN7 IGF1R IGF1R CD14 CD14 ABCB11 ABCB11 GRIN1 GRIN1 PENK PENK EPS8 EPS8 AVP AVP KCNMB1 KCNMB1 CA3 CA3 NPPC NPPC GABBR1 GABBR1 CHRNB2 CHRNB2 VCAM1 VCAM1 BAK1 BAK1 FGF19 FGF19 PSMD14 PSMD14 SPINK1 SPINK1 SOD1 SOD1 ADCYAP1R1 ADCYAP1R1 CRHR1 CRHR1 OPRM1 OPRM1 SLC2A4 SLC2A4 NLRP3 NLRP3 TACR1 TACR1 ABAT ABAT TJP1 TJP1 RGS2 RGS2 MGMT MGMT PPARA PPARA CBL CBL SLC23A2 SLC23A2 ARSA ARSA GATA3 GATA3 TBXA2R TBXA2R FYN FYN KCNC2 KCNC2 GLRA2 GLRA2 ADH7 ADH7 DMAP1 DMAP1 EHMT2 EHMT2 TUFM TUFM ENSPCOP00000004143 ENSPCOP00000004143 ITPR2 ITPR2 GRIN3A GRIN3A DRD2 DRD2 ENSPCOP00000002148 ENSPCOP00000002148 CYBB CYBB GRIN2A GRIN2A CLDN18 CLDN18 S100A8 S100A8 CPT1A CPT1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
G6PDGlucose-6-phosphate dehydrogenase. (558 aa)
CSF3Colony stimulating factor 3. (199 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (502 aa)
ENSPCOP00000030811Sod_Cu domain-containing protein. (132 aa)
BADBCL2 associated agonist of cell death. (168 aa)
FGFR2Fibroblast growth factor receptor. (797 aa)
UNC79Unc-79 homolog, NALCN channel complex subunit. (2440 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
ST6GAL1ST6 beta-galactoside alpha-2,6-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (406 aa)
OGG18-oxoguanine DNA glycosylase. (380 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1605 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (967 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
SLC10A1Solute carrier family 10 member 1. (348 aa)
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (333 aa)
POLBDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (333 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1485 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
MAOBAmine oxidase. (528 aa)
CYP7A1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa)
RGS19Regulator of G protein signaling 19. (217 aa)
DNMT3ADNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (912 aa)
GLRA1Glycine receptor alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (456 aa)
GOT2Aspartate aminotransferase. (370 aa)
THTyrosine hydroxylase. (497 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
GNRH1Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (92 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1180 aa)
NR0B2Nuclear receptor subfamily 0 group B member 2. (256 aa)
RARARetinoic acid receptor alpha. (472 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (395 aa)
RGS7Regulator of G protein signaling 7. (487 aa)
TYMSThymidylate synthetase. (313 aa)
TP53INP1Tumor protein p53 inducible nuclear protein 1. (241 aa)
DBHDopamine beta-hydroxylase. (620 aa)
CLDN7Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
IGF1RTyrosine-protein kinase receptor. (1350 aa)
CD14Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (375 aa)
ABCB11ATP binding cassette subfamily B member 11. (1288 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (960 aa)
PENKProenkephalin. (267 aa)
EPS8Epidermal growth factor receptor pathway substrate 8. (711 aa)
AVPArginine vasopressin. (116 aa)
KCNMB1Potassium calcium-activated channel subfamily M regulatory beta subunit 1. (191 aa)
CA3Carbonic anhydrase 3; Belongs to the alpha-carbonic anhydrase family. (260 aa)
NPPCNatriuretic peptide C. (126 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (962 aa)
CHRNB2Cholinergic receptor nicotinic beta 2 subunit. (502 aa)
VCAM1Vascular cell adhesion molecule 1. (739 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (219 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (274 aa)
SPINK1Serine peptidase inhibitor, Kazal type 1. (78 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (153 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (524 aa)
CRHR1Corticotropin releasing hormone receptor 1; Belongs to the G-protein coupled receptor 2 family. (415 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (479 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
NLRP3NLR family pyrin domain containing 3. (1036 aa)
TACR1Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
ABAT4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1768 aa)
RGS2Regulator of G protein signaling 2. (211 aa)
MGMTO-6-methylguanine-DNA methyltransferase. (241 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
CBLCbl proto-oncogene. (891 aa)
SLC23A2Solute carrier family 23 member 2. (632 aa)
ARSAArylsulfatase A. (423 aa)
GATA3Uncharacterized protein. (444 aa)
TBXA2RThromboxane A2 receptor; Belongs to the G-protein coupled receptor 1 family. (343 aa)
FYNTyrosine-protein kinase. (537 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (638 aa)
GLRA2Glycine receptor alpha 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (451 aa)
ADH7Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide. (386 aa)
DMAP1DNA methyltransferase 1 associated protein 1. (468 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1267 aa)
TUFMElongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (455 aa)
ENSPCOP00000004143Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (136 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2702 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1115 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
ENSPCOP00000002148Uncharacterized protein. (118 aa)
CYBBCytochrome b-245 beta chain. (533 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1462 aa)
CLDN18Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa)
S100A8S100 calcium binding protein A8; Belongs to the S-100 family. (89 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (697 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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