STRINGSTRING
CCBE1 CCBE1 STIM1 STIM1 ETS1 ETS1 ECSCR ECSCR SIRT6 SIRT6 ENSPCOP00000031789 ENSPCOP00000031789 FGF18 FGF18 VEGFD VEGFD VASH1 VASH1 HPSE HPSE YJEFN3 YJEFN3 FGF2 FGF2 LRG1 LRG1 DDAH1 DDAH1 HSPB1 HSPB1 SFRP1 SFRP1 PIK3CD PIK3CD STAT3 STAT3 SEMA6A SEMA6A PRKCB PRKCB NPPB NPPB PRKCA PRKCA PLXND1 PLXND1 HRG HRG C5 C5 ECM1 ECM1 SERPINF1 SERPINF1 PDCD10 PDCD10 GDF2 GDF2 FOXC1 FOXC1 AKT3 AKT3 SYNJ2BP SYNJ2BP GHRL GHRL AGGF1 AGGF1 ERBB2 ERBB2 SPRED1 SPRED1 HIPK1 HIPK1 SIRT1 SIRT1 PTK2B PTK2B GATA4 GATA4 WARS2 WARS2 LOC105822688 LOC105822688 GATA6 GATA6 RTN4 RTN4 THBS4 THBS4 SPRY2 SPRY2 EGLN1 EGLN1 SP1 SP1 GHSR GHSR FOXC2 FOXC2 AMOT AMOT NF1 NF1 ATF2 ATF2 CD40 CD40 CCN6 CCN6 EPHA1 EPHA1 TNMD TNMD CREB3L1 CREB3L1 MYDGF MYDGF FASLG FASLG ENSPCOP00000025432 ENSPCOP00000025432 MECP2 MECP2 KLF2 KLF2 THBS1 THBS1 CXCL8 CXCL8 PLCG1 PLCG1 F3 F3 CXCL10 CXCL10 ADM ADM VEGFA VEGFA BMPER BMPER PKM PKM CHRNA7 CHRNA7 EMILIN1 EMILIN1 ENSPCOP00000023392 ENSPCOP00000023392 SASH1 SASH1 SMOC2 SMOC2 ACVRL1 ACVRL1 CTNNB1 CTNNB1 KRIT1 KRIT1 EMILIN2 EMILIN2 FOXO4 FOXO4 GADD45A GADD45A EPN2 EPN2 CYP1B1 CYP1B1 PTGIS PTGIS AGO2 AGO2 GTF2I GTF2I CXCR3 CXCR3 TMIGD2 TMIGD2 PDE3B PDE3B VEGFC VEGFC ENG ENG PML PML AGO1 AGO1 DAB2IP DAB2IP TSPAN12 TSPAN12 TNN TNN SEMA4A SEMA4A PROK1 PROK1 RAMP2 RAMP2 CDH5 CDH5 SFRP2 SFRP2 TNFSF12 TNFSF12 CD160 CD160 ADAMTS1 ADAMTS1 HGF HGF SPINK5 SPINK5 ADAMTS9 ADAMTS9 COL4A2 COL4A2 ANGPT2 ANGPT2 TIE1 TIE1 CX3CR1 CX3CR1 ADGRB2 ADGRB2 HOXA5 HOXA5 ITGB8 ITGB8 NRP1 NRP1 FLT1 FLT1 RECK RECK RGCC RGCC PIK3CB PIK3CB SLC12A2 SLC12A2 SPARC SPARC MAPK7 MAPK7 NR2E1 NR2E1 ISM1 ISM1 ALOX5 ALOX5 TNF TNF EFNA1 EFNA1 ADGRA2 ADGRA2 ENSPCOP00000014590 ENSPCOP00000014590 GPNMB GPNMB CEACAM1 CEACAM1 ATP2B4 ATP2B4 PRKD2 PRKD2 ABCC8 ABCC8 VASH2 VASH2 JAK1 JAK1 RNH1 RNH1 CNMD CNMD RRAS RRAS ISL1 ISL1 C3 C3 HK2 HK2 APELA APELA ERAP1 ERAP1 DCN DCN MINAR1 MINAR1 ADM2 ADM2 JUP JUP ENSPCOP00000012342 ENSPCOP00000012342 ANGPTL3 ANGPTL3 TJP1 TJP1 MDK MDK RHOJ RHOJ ROCK2 ROCK2 NPR1 NPR1 JMJD8 JMJD8 WARS1 WARS1 IL1B IL1B CHI3L1 CHI3L1 CCM2 CCM2 SERPINE1 SERPINE1 SPHK1 SPHK1 NTRK1 NTRK1 FGF1 FGF1 ANGPTL4 ANGPTL4 PPP1R16B PPP1R16B EPHA2 EPHA2 SEMA3E SEMA3E ANGPT4 ANGPT4 NODAL NODAL PGF PGF NOS3 NOS3 HGS HGS ENSPCOP00000009588 ENSPCOP00000009588 TLR3 TLR3 COL4A3 COL4A3 AQP1 AQP1 ZC3H12A ZC3H12A KLF4 KLF4 TBXA2R TBXA2R PTPRM PTPRM TEK TEK VEGFB VEGFB NINJ1 NINJ1 IL10 IL10 STAT1 STAT1 ROCK1 ROCK1 WNT5A WNT5A ENPP2 ENPP2 PLK2 PLK2 ITGB2 ITGB2 HSPG2 HSPG2 EMP2 EMP2 MTDH MTDH RAPGEF3 RAPGEF3 PAK4 PAK4 ITGA5 ITGA5 LEP LEP HTATIP2 HTATIP2 SARS1 SARS1 TBC1D31 TBC1D31 SMAD1 SMAD1 CXCL13 CXCL13 KDR KDR STAB1 STAB1 PDPK1 PDPK1 EPN1 EPN1 HIF1A HIF1A DLL1 DLL1 GLUL GLUL HMOX1 HMOX1 ENSPCOP00000004135 ENSPCOP00000004135 ENSPCOP00000004028 ENSPCOP00000004028 XBP1 XBP1 HIPK2 HIPK2 CCL24 CCL24 THBS2 THBS2 ENSPCOP00000003159 ENSPCOP00000003159 BTG1 BTG1 HHEX HHEX ENSPCOP00000002776 ENSPCOP00000002776 APLNR APLNR NFE2L2 NFE2L2 PRKD1 PRKD1 CYBB CYBB LOC105822640 LOC105822640 GATA2 GATA2 ZNF304 ZNF304 JCAD JCAD ENSPCOP00000001819 ENSPCOP00000001819 NAXE NAXE CELA1 CELA1 FOXJ2 FOXJ2 EMC10 EMC10 RHOB RHOB GRN GRN TGFBR2 TGFBR2 TGFB2 TGFB2 CTSH CTSH SULF1 SULF1 E2F2 E2F2 HYAL1 HYAL1 HMGA2 HMGA2 NIBAN2 NIBAN2 HSPB6 HSPB6 GPR4 GPR4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CCBE1Collagen and calcium binding EGF domains 1. (408 aa)
STIM1Stromal interaction molecule 1. (784 aa)
ETS1ETS proto-oncogene 1, transcription factor. (485 aa)
ECSCRUncharacterized protein. (205 aa)
SIRT6Sirtuin 6. (305 aa)
ENSPCOP00000031789Uncharacterized protein. (227 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (319 aa)
VASH1Vasohibin 1. (363 aa)
HPSEHeparanase. (395 aa)
YJEFN3YjeF N-terminal domain-containing protein. (293 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (394 aa)
LRG1Leucine rich alpha-2-glycoprotein 1. (347 aa)
DDAH1Dimethylarginine dimethylaminohydrolase 1. (285 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (206 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
STAT3Signal transducer and activator of transcription. (796 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1047 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
NPPBNatriuretic peptide B. (132 aa)
PRKCAUncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (575 aa)
PLXND1Plexin D1. (1928 aa)
HRGHistidine rich glycoprotein. (468 aa)
C5Complement C5. (1527 aa)
ECM1Extracellular matrix protein 1. (570 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (418 aa)
PDCD10Programmed cell death 10. (186 aa)
GDF2Growth differentiation factor 2. (427 aa)
FOXC1Forkhead box C1. (535 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
SYNJ2BPSynaptojanin 2 binding protein. (134 aa)
GHRLGhrelin and obestatin prepropeptide. (116 aa)
AGGF1Uncharacterized protein. (717 aa)
ERBB2Receptor protein-tyrosine kinase. (1252 aa)
SPRED1Sprouty related EVH1 domain containing 1. (444 aa)
HIPK1Homeodomain interacting protein kinase 1. (1131 aa)
SIRT1Sirtuin 1. (743 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (967 aa)
GATA4GATA binding protein 4. (445 aa)
WARS2Tryptophanyl tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (360 aa)
LOC105822688Uncharacterized protein. (54 aa)
GATA6GATA binding protein 6. (593 aa)
RTN4Reticulon. (1195 aa)
THBS4Thrombospondin 4. (959 aa)
SPRY2Sprouty RTK signaling antagonist 2. (314 aa)
EGLN1Uncharacterized protein. (427 aa)
SP1Sp1 transcription factor. (788 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (364 aa)
FOXC2Forkhead box C2. (503 aa)
AMOTAngiomotin. (1083 aa)
NF1Neurofibromin 1. (2841 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
CD40CD40 molecule. (281 aa)
CCN6CTCK domain-containing protein. (130 aa)
EPHA1EPH receptor A1. (942 aa)
TNMDTenomodulin. (320 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (520 aa)
MYDGFMyeloid derived growth factor. (173 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (278 aa)
ENSPCOP00000025432Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (747 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (500 aa)
KLF2Kruppel like factor 2. (356 aa)
THBS1Thrombospondin 1. (1185 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1304 aa)
F3Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (294 aa)
CXCL10C-X-C motif chemokine. (98 aa)
ADMAdrenomedullin. (182 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa)
BMPERBMP binding endothelial regulator. (704 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
CHRNA7Uncharacterized protein. (531 aa)
EMILIN1Elastin microfibril interfacer 1. (1022 aa)
ENSPCOP00000023392Uncharacterized protein. (157 aa)
SASH1SAM and SH3 domain containing 1. (1248 aa)
SMOC2SPARC related modular calcium binding 2. (457 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
CTNNB1Catenin beta 1. (781 aa)
KRIT1ANK_REP_REGION domain-containing protein. (723 aa)
EMILIN2Elastin microfibril interfacer 2. (1061 aa)
FOXO4Forkhead box O4. (506 aa)
GADD45AGrowth arrest and DNA damage inducible alpha. (165 aa)
EPN2ENTH domain-containing protein. (641 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
PTGISProstacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa)
AGO2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (869 aa)
GTF2IGeneral transcription factor IIi. (998 aa)
CXCR3C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (401 aa)
TMIGD2Transmembrane and immunoglobulin domain containing 2. (225 aa)
PDE3BPhosphodiesterase. (1047 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (367 aa)
ENGEndoglin. (657 aa)
PMLPromyelocytic leukemia. (887 aa)
AGO1Argonaute RISC component 1; Belongs to the argonaute family. (857 aa)
DAB2IPDAB2 interacting protein. (1209 aa)
TSPAN12Tetraspanin. (269 aa)
TNNTenascin N. (1299 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (761 aa)
PROK1Prokineticin 1. (105 aa)
RAMP2Receptor activity modifying protein 2. (179 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (786 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
TNFSF12TNF superfamily member 12; Belongs to the tumor necrosis factor family. (249 aa)
CD160CD160 molecule. (220 aa)
ADAMTS1ADAM metallopeptidase with thrombospondin type 1 motif 1. (965 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (703 aa)
SPINK5Uncharacterized protein. (775 aa)
ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif 9. (1838 aa)
COL4A2Collagen type IV alpha 2 chain. (1711 aa)
ANGPT2Angiopoietin 2. (496 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1143 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (379 aa)
ADGRB2Adhesion G protein-coupled receptor B2; Belongs to the G-protein coupled receptor 2 family. (1564 aa)
HOXA5Homeobox A5. (270 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (768 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa)
RECKReversion inducing cysteine rich protein with kazal motifs. (969 aa)
RGCCRegulator of cell cycle. (137 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
SLC12A2Solute carrier family 12 member 2. (1153 aa)
SPARCSecreted protein acidic and cysteine rich. (303 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (802 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (421 aa)
ISM1Isthmin 1. (463 aa)
ALOX5Arachidonate 5-lipoxygenase. (675 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (235 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
ADGRA2Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1314 aa)
ENSPCOP00000014590Uncharacterized protein. (118 aa)
GPNMBGlycoprotein nmb. (567 aa)
CEACAM1Uncharacterized protein. (523 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1204 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
ABCC8ATP binding cassette subfamily C member 8. (1582 aa)
VASH2Vasohibin 2. (355 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
RNH1Ribonuclease/angiogenin inhibitor 1. (456 aa)
CNMDChondromodulin. (287 aa)
RRASRAS related. (220 aa)
ISL1ISL LIM homeobox 1. (349 aa)
C3Complement C3. (1551 aa)
HK2Hexokinase 2. (841 aa)
APELAApelin receptor early endogenous ligand. (54 aa)
ERAP1Aminopeptidase. (915 aa)
DCNDecorin; May affect the rate of fibrils formation. (290 aa)
MINAR1Membrane integral NOTCH2 associated receptor 1. (714 aa)
ADM2Adrenomedullin 2. (148 aa)
JUPJunction plakoglobin. (745 aa)
ENSPCOP00000012342RING-type domain-containing protein. (80 aa)
ANGPTL3Angiopoietin like 3. (460 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1768 aa)
MDKMidkine. (143 aa)
RHOJRas homolog family member J. (215 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1361 aa)
NPR1Guanylate cyclase. (1058 aa)
JMJD8Jumonji domain containing 8. (280 aa)
WARS1Tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (419 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
CHI3L1Chitinase 3 like 1; Belongs to the glycosyl hydrolase 18 family. (385 aa)
CCM2CCM2 scaffold protein. (467 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (402 aa)
SPHK1Sphingosine kinase 1. (469 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
ANGPTL4Angiopoietin like 4. (411 aa)
PPP1R16BProtein phosphatase 1 regulatory subunit 16B. (568 aa)
EPHA2EPH receptor A2. (976 aa)
SEMA3ESema domain-containing protein; Belongs to the semaphorin family. (390 aa)
ANGPT4Angiopoietin 4. (499 aa)
NODALNodal growth differentiation factor. (348 aa)
PGFPlacental growth factor; Belongs to the PDGF/VEGF growth factor family. (220 aa)
NOS3Nitric oxide synthase 3. (994 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa)
ENSPCOP00000009588Uncharacterized protein. (316 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (905 aa)
COL4A3Collagen type IV alpha 3 chain. (1545 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (598 aa)
KLF4Uncharacterized protein. (486 aa)
TBXA2RThromboxane A2 receptor; Belongs to the G-protein coupled receptor 1 family. (343 aa)
PTPRMProtein tyrosine phosphatase receptor type M. (1440 aa)
TEKTEK receptor tyrosine kinase. (1125 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (188 aa)
NINJ1Ninjurin 1. (152 aa)
IL10Interleukin 10. (178 aa)
STAT1Signal transducer and activator of transcription. (794 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1316 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
ENPP2Ectonucleotide pyrophosphatase/phosphodiesterase 2. (911 aa)
PLK2Serine/threonine-protein kinase PLK. (685 aa)
ITGB2Integrin beta. (764 aa)
HSPG2Heparan sulfate proteoglycan 2. (4370 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
MTDHMetadherin. (580 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (923 aa)
PAK4Non-specific serine/threonine protein kinase. (588 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1041 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
HTATIP2HIV-1 Tat interactive protein 2. (275 aa)
SARS1Seryl-tRNA synthetase. (538 aa)
TBC1D31TBC1 domain family member 31. (1062 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
CXCL13C-X-C motif chemokine. (110 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
STAB1Stabilin 1. (2566 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (558 aa)
EPN1Epsin 1. (575 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (826 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
GLULGlutamine synthetase. (373 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
ENSPCOP00000004135Uncharacterized protein. (520 aa)
ENSPCOP00000004028ENTH domain-containing protein. (534 aa)
XBP1BZIP domain-containing protein. (377 aa)
HIPK2Homeodomain interacting protein kinase 2. (1187 aa)
CCL24C-C motif chemokine ligand 24. (119 aa)
THBS2Thrombospondin 2. (1172 aa)
ENSPCOP00000003159IGFBP N-terminal domain-containing protein. (230 aa)
BTG1BTG anti-proliferation factor 1. (171 aa)
HHEXHematopoietically expressed homeobox. (271 aa)
ENSPCOP00000002776Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (330 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (606 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (860 aa)
CYBBCytochrome b-245 beta chain. (533 aa)
LOC105822640Integrin beta; Belongs to the integrin beta chain family. (454 aa)
GATA2GATA binding protein 2. (445 aa)
ZNF304Zinc finger protein 304. (690 aa)
JCADJunctional cadherin 5 associated. (1332 aa)
ENSPCOP00000001819Uncharacterized protein. (406 aa)
NAXENAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (288 aa)
CELA1Chymotrypsin like elastase 1; Belongs to the peptidase S1 family. (257 aa)
FOXJ2Forkhead box J2. (527 aa)
EMC10ER membrane protein complex subunit 10. (261 aa)
RHOBRas homolog family member B. (196 aa)
GRNGranulin precursor. (591 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (336 aa)
SULF1Sulfatase 1. (863 aa)
E2F2E2F transcription factor 2. (435 aa)
HYAL1Hyaluronidase. (435 aa)
HMGA2Uncharacterized protein. (117 aa)
NIBAN2Niban apoptosis regulator 2. (748 aa)
HSPB6Heat shock protein family B (small) member 6; Belongs to the small heat shock protein (HSP20) family. (162 aa)
GPR4G protein-coupled receptor 4; Belongs to the G-protein coupled receptor 1 family. (362 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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