STRINGSTRING
IL1B IL1B PPARD PPARD PLA2G3 PLA2G3 MLXIPL MLXIPL NR1H2 NR1H2 APOC2 APOC2 GHSR GHSR NR1H3 NR1H3 APOA5 APOA5 PPARGC1A PPARGC1A AVP AVP ABCD2 ABCD2 AKT2 AKT2 ADIPOQ ADIPOQ SLC45A3 SLC45A3 PPARG PPARG PPARA PPARA ABCD1 ABCD1 CD74 CD74 PTGS2 PTGS2 LPGAT1 LPGAT1 PLIN5 PLIN5 MLYCD MLYCD AVPR1A AVPR1A FABP1 FABP1 NR4A3 NR4A3 MID1IP1 MID1IP1 CPT1A CPT1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
PPARDPeroxisome proliferator activated receptor delta. (440 aa)
PLA2G3Phospholipase A2 group III. (506 aa)
MLXIPLMLX interacting protein like. (856 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (459 aa)
APOC2Apolipoprotein C2. (101 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (364 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (454 aa)
APOA5Apolipoprotein A5. (371 aa)
PPARGC1APPARG coactivator 1 alpha. (809 aa)
AVPArginine vasopressin. (116 aa)
ABCD2ATP binding cassette subfamily D member 2. (740 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
SLC45A3Solute carrier family 45 member 3. (553 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (502 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
ABCD1ATP binding cassette subfamily D member 1. (746 aa)
CD74CD74 molecule. (298 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
LPGAT1Lysophosphatidylglycerol acyltransferase 1. (327 aa)
PLIN5Perilipin; Belongs to the perilipin family. (450 aa)
MLYCDMalonyl-CoA decarboxylase. (498 aa)
AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (410 aa)
FABP1FABP domain-containing protein. (69 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (645 aa)
MID1IP1MID1 interacting protein 1. (184 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (697 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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