26 items (Propithecus coquereli) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MSTN	Myostatin. (376 aa)
	LARGE2	LARGE xylosyl- and glucuronyltransferase 2. (697 aa)
	TRIM32	Uncharacterized protein. (653 aa)
	LARGE1	LARGE xylosyl- and glucuronyltransferase 1. (756 aa)
	LAMP2	Lysosomal associated membrane protein 2. (414 aa)
	ENSPCOP00000004143	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (136 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	CFL2	Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
	HIF1A	Hypoxia inducible factor 1 subunit alpha. (826 aa)
	FXN	Frataxin. (211 aa)
	FKBP14	Peptidylprolyl isomerase. (211 aa)
	SGCZ	Sarcoglycan zeta. (312 aa)
	MTM1	Myotubularin 1. (603 aa)
	ENSPCOP00000014148	Uncharacterized protein. (733 aa)
	SOD1	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (153 aa)
	CHRNA1	Cholinergic receptor nicotinic alpha 1 subunit. (479 aa)
	LOX	Lysyl oxidase. (416 aa)
	SRF	Serum response factor. (508 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	ENSPCOP00000024978	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (148 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
	ENSPCOP00000027120	Uncharacterized protein. (1243 aa)
	LOC105826437	E3 ubiquitin-protein ligase TRIM32. (653 aa)
	BAG3	BCL2 associated athanogene 3. (577 aa)
	CSRP3	Cysteine and glycine rich protein 3. (194 aa)
	ENSPCOP00000030811	Sod_Cu domain-containing protein. (132 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAV1	CAV3	ENSPCOP00000025045	ENSPCOP00000004480	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.902
CAV1	MTM1	ENSPCOP00000025045	ENSPCOP00000011591	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Myotubularin 1.	0.433
CAV3	CAV1	ENSPCOP00000004480	ENSPCOP00000025045	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.902
CAV3	ENSPCOP00000014148	ENSPCOP00000004480	ENSPCOP00000014148	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein.	0.540
CAV3	ENSPCOP00000027120	ENSPCOP00000004480	ENSPCOP00000027120	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein.	0.540
CAV3	MTM1	ENSPCOP00000004480	ENSPCOP00000011591	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Myotubularin 1.	0.455
CAV3	SGCZ	ENSPCOP00000004480	ENSPCOP00000009549	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Sarcoglycan zeta.	0.517
ENSPCOP00000014148	CAV3	ENSPCOP00000014148	ENSPCOP00000004480	Uncharacterized protein.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.540
ENSPCOP00000014148	ENSPCOP00000027120	ENSPCOP00000014148	ENSPCOP00000027120	Uncharacterized protein.	Uncharacterized protein.	0.876
ENSPCOP00000027120	CAV3	ENSPCOP00000027120	ENSPCOP00000004480	Uncharacterized protein.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.540
ENSPCOP00000027120	ENSPCOP00000014148	ENSPCOP00000027120	ENSPCOP00000014148	Uncharacterized protein.	Uncharacterized protein.	0.876
HIF1A	LAMP2	ENSPCOP00000004706	ENSPCOP00000003635	Hypoxia inducible factor 1 subunit alpha.	Lysosomal associated membrane protein 2.	0.524
HIF1A	TGFB1	ENSPCOP00000004706	ENSPCOP00000023065	Hypoxia inducible factor 1 subunit alpha.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.488
LAMP2	HIF1A	ENSPCOP00000003635	ENSPCOP00000004706	Lysosomal associated membrane protein 2.	Hypoxia inducible factor 1 subunit alpha.	0.524
LARGE1	LARGE2	ENSPCOP00000002284	ENSPCOP00000000395	LARGE xylosyl- and glucuronyltransferase 1.	LARGE xylosyl- and glucuronyltransferase 2.	0.846
LARGE2	LARGE1	ENSPCOP00000000395	ENSPCOP00000002284	LARGE xylosyl- and glucuronyltransferase 2.	LARGE xylosyl- and glucuronyltransferase 1.	0.846
MTM1	CAV1	ENSPCOP00000011591	ENSPCOP00000025045	Myotubularin 1.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.433
MTM1	CAV3	ENSPCOP00000011591	ENSPCOP00000004480	Myotubularin 1.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.455
SGCZ	CAV3	ENSPCOP00000009549	ENSPCOP00000004480	Sarcoglycan zeta.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.517
TGFB1	HIF1A	ENSPCOP00000023065	ENSPCOP00000004706	Transforming growth factor beta; Belongs to the TGF-beta family.	Hypoxia inducible factor 1 subunit alpha.	0.488