STRINGSTRING
ACVR1B ACVR1B MELK MELK NLK NLK MEX3B MEX3B ATR ATR MAP3K3 MAP3K3 FLT1 FLT1 DDR1 DDR1 TAOK2 TAOK2 ATM ATM FAM20C FAM20C LOC105815896 LOC105815896 EPHA8 EPHA8 PIM3 PIM3 SMG1 SMG1 EGFR EGFR FGR FGR SRC SRC DDR2 DDR2 INSRR INSRR EPHB3 EPHB3 TNIK TNIK NEK6 NEK6 MAP3K9 MAP3K9 IRAK3 IRAK3 PDGFRA PDGFRA CDK5 CDK5 UHMK1 UHMK1 STK39 STK39 CAMK4 CAMK4 FES FES TRIM28 TRIM28 RIPK3 RIPK3 STK16 STK16 PDGFRB PDGFRB TRPM7 TRPM7 MAP3K10 MAP3K10 CSK CSK FGFR2 FGFR2 BTK BTK CLK2 CLK2 GRK1 GRK1 ENSPCOP00000029403 ENSPCOP00000029403 IRAK1 IRAK1 MAP3K11 MAP3K11 MAP3K12 MAP3K12 TXK TXK AKT1 AKT1 MAP3K13 MAP3K13 MAP3K21 MAP3K21 MKNK1 MKNK1 MINK1 MINK1 FGFR4 FGFR4 ERBB2 ERBB2 FGFR3 FGFR3 PTK2B PTK2B BMX BMX ZAP70 ZAP70 CHEK2 CHEK2 CSF1R CSF1R PEAK1 PEAK1 EPHA1 EPHA1 MAPKAPK3 MAPKAPK3 TAOK1 TAOK1 LMTK2 LMTK2 PTK2 PTK2 INSR INSR STK33 STK33 EIF2AK3 EIF2AK3 WNK2 WNK2 CAMK2A CAMK2A ULK3 ULK3 LYN LYN WNK3 WNK3 LRRK2 LRRK2 PINK1 PINK1 FLT3 FLT3 SRMS SRMS RIPK1 RIPK1 RIOK2 RIOK2 LTK LTK KIT KIT MAPKAPK5 MAPKAPK5 MARK3 MARK3 HIPK4 HIPK4 EEF2K EEF2K ERN1 ERN1 GSK3B GSK3B CLK3 CLK3 ATP13A2 ATP13A2 VRK2 VRK2 CAD CAD DAPK3 DAPK3 CAMK2G CAMK2G STK25 STK25 AATK AATK MUSK MUSK ENSPCOP00000022199 ENSPCOP00000022199 STK24 STK24 TAOK3 TAOK3 IGF1R IGF1R CAMK2D CAMK2D GRK5 GRK5 CDKL5 CDKL5 VRK1 VRK1 EIF2AK4 EIF2AK4 PAK2 PAK2 MKNK2 MKNK2 EPHB4 EPHB4 DYRK1B DYRK1B MYO3A MYO3A PIKFYVE PIKFYVE ENSPCOP00000019705 ENSPCOP00000019705 MAP4K1 MAP4K1 STK11 STK11 PDPK1 PDPK1 KDR KDR RB1CC1 RB1CC1 HTATIP2 HTATIP2 ALK ALK EIF2AK2 EIF2AK2 MAPKAPK2 MAPKAPK2 MYLK2 MYLK2 ULK2 ULK2 CAMK2B CAMK2B PAK1 PAK1 DAPK2 DAPK2 MARK2 MARK2 AURKA AURKA STK17B STK17B GRK7 GRK7 MAPK3 MAPK3 PIM1 PIM1 STK26 STK26 CLK4 CLK4 FYN FYN TEK TEK DAPK1 DAPK1 SYK SYK ATG101 ATG101 SLK SLK FLT4 FLT4 LCK LCK AAK1 AAK1 ENSPCOP00000010360 ENSPCOP00000010360 TNK1 TNK1 NTRK1 NTRK1 PIM2 PIM2 NEK2 NEK2 HCK HCK ENSPCOP00000013124 ENSPCOP00000013124 CLK1 CLK1 EIF2S1 EIF2S1 TSSK4 TSSK4 ROS1 ROS1 PRKD2 PRKD2 STK4 STK4 FER FER AURKB AURKB EPHB1 EPHB1 STK10 STK10 DYRK1A DYRK1A TRIM24 TRIM24 ENSPCOP00000015643 ENSPCOP00000015643 CDK12 CDK12 ENSPCOP00000000463 ENSPCOP00000000463 ULK1 ULK1 NTRK2 NTRK2 MAK MAK MTOR MTOR PRKD1 PRKD1 CAMKK2 CAMKK2 OXSR1 OXSR1 FGFR1 FGFR1 SIK2 SIK2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (545 aa)
MELKNon-specific serine/threonine protein kinase. (493 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)
MEX3BMex-3 RNA binding family member B. (575 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2643 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (653 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa)
DDR1Discoidin domain receptor tyrosine kinase 1. (913 aa)
TAOK2TAO kinase 2. (1237 aa)
ATMATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2635 aa)
FAM20CFAM20C golgi associated secretory pathway kinase. (584 aa)
LOC105815896S1 motif domain-containing protein. (295 aa)
EPHA8EPH receptor A8. (1006 aa)
PIM3Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (326 aa)
SMG1SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3290 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
FGRTyrosine-protein kinase. (495 aa)
SRCTyrosine-protein kinase. (543 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (855 aa)
INSRRTyrosine-protein kinase receptor. (1272 aa)
EPHB3EPH receptor B3. (1009 aa)
TNIKTRAF2 and NCK interacting kinase. (1363 aa)
NEK6NIMA related kinase 6; Belongs to the protein kinase superfamily. (313 aa)
MAP3K9Mitogen-activated protein kinase kinase kinase. (1103 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (505 aa)
PDGFRAPlatelet derived growth factor receptor alpha; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1027 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
UHMK1U2AF homology motif kinase 1. (419 aa)
STK39Serine/threonine kinase 39. (522 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (473 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (821 aa)
TRIM28Tripartite motif containing 28. (833 aa)
RIPK3Receptor interacting serine/threonine kinase 3. (516 aa)
STK16Serine/threonine kinase 16. (349 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1105 aa)
TRPM7Transient receptor potential cation channel subfamily M member 7. (1683 aa)
MAP3K10Mitogen-activated protein kinase kinase kinase. (959 aa)
CSKTyrosine-protein kinase. (450 aa)
FGFR2Fibroblast growth factor receptor. (797 aa)
BTKTyrosine-protein kinase. (647 aa)
CLK2CDC like kinase 2; Belongs to the protein kinase superfamily. (500 aa)
GRK1G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (564 aa)
ENSPCOP00000029403Protein kinase domain-containing protein. (429 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (713 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase. (847 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (891 aa)
TXKTyrosine-protein kinase. (581 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13. (958 aa)
MAP3K21Mitogen-activated protein kinase kinase kinase. (1038 aa)
MKNK1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (427 aa)
MINK1Misshapen like kinase 1. (1328 aa)
FGFR4Fibroblast growth factor receptor. (797 aa)
ERBB2Receptor protein-tyrosine kinase. (1252 aa)
FGFR3Fibroblast growth factor receptor. (807 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (967 aa)
BMXTyrosine-protein kinase. (627 aa)
ZAP70Tyrosine-protein kinase. (617 aa)
CHEK2Checkpoint kinase 2. (571 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (964 aa)
PEAK1Pseudopodium enriched atypical kinase 1. (1752 aa)
EPHA1EPH receptor A1. (942 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (384 aa)
TAOK1TAO kinase 1. (1001 aa)
LMTK2Lemur tyrosine kinase 2. (1466 aa)
PTK2Protein tyrosine kinase 2. (1089 aa)
INSRInsulin receptor. (1192 aa)
STK33Serine/threonine kinase 33. (477 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1115 aa)
WNK2WNK lysine deficient protein kinase 2. (2211 aa)
CAMK2AProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (471 aa)
ULK3Unc-51 like kinase 3. (486 aa)
LYNTyrosine-protein kinase. (512 aa)
WNK3WNK lysine deficient protein kinase 3. (1791 aa)
LRRK2Leucine rich repeat kinase 2. (2427 aa)
PINK1PTEN induced kinase 1. (581 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (949 aa)
SRMSTyrosine-protein kinase. (496 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (643 aa)
RIOK2RIO kinase 2. (552 aa)
LTKTyrosine-protein kinase receptor. (888 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
MAPKAPK5MAPK activated protein kinase 5. (478 aa)
MARK3Non-specific serine/threonine protein kinase. (774 aa)
HIPK4Homeodomain interacting protein kinase 4; Belongs to the protein kinase superfamily. (397 aa)
EEF2KEukaryotic elongation factor 2 kinase. (725 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (935 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (390 aa)
CLK3CDC like kinase 3. (638 aa)
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1174 aa)
VRK2VRK serine/threonine kinase 2. (391 aa)
CADCarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2227 aa)
DAPK3Death associated protein kinase 3; Belongs to the protein kinase superfamily. (454 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (600 aa)
STK25Serine/threonine kinase 25. (426 aa)
AATKApoptosis associated tyrosine kinase. (1335 aa)
MUSKMuscle associated receptor tyrosine kinase. (826 aa)
ENSPCOP00000022199Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (282 aa)
STK24Serine/threonine kinase 24. (443 aa)
TAOK3TAO kinase 3. (898 aa)
IGF1RTyrosine-protein kinase receptor. (1350 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (503 aa)
GRK5G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (590 aa)
CDKL5Cyclin dependent kinase like 5. (933 aa)
VRK1VRK serine/threonine kinase 1; Belongs to the protein kinase superfamily. (396 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1650 aa)
PAK2Non-specific serine/threonine protein kinase. (492 aa)
MKNK2MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily. (468 aa)
EPHB4EPH receptor B4. (987 aa)
DYRK1BDual specificity tyrosine phosphorylation regulated kinase 1B. (629 aa)
MYO3AMyosin IIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1426 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2053 aa)
ENSPCOP00000019705Uncharacterized protein. (583 aa)
MAP4K1Mitogen-activated protein kinase kinase kinase kinase 1; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (819 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (442 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (558 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
RB1CC1RB1 inducible coiled-coil 1. (1590 aa)
HTATIP2HIV-1 Tat interactive protein 2. (275 aa)
ALKTyrosine-protein kinase receptor. (1578 aa)
EIF2AK2Eukaryotic translation initiation factor 2 alpha kinase 2. (549 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (400 aa)
MYLK2Myosin light chain kinase 2. (596 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1036 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (665 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
DAPK2Death associated protein kinase 2; Belongs to the protein kinase superfamily. (488 aa)
MARK2Non-specific serine/threonine protein kinase. (788 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (402 aa)
STK17BSerine/threonine kinase 17b; Belongs to the protein kinase superfamily. (372 aa)
GRK7G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (553 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
PIM1Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (401 aa)
STK26Serine/threonine kinase 26. (372 aa)
CLK4CDC like kinase 4; Belongs to the protein kinase superfamily. (436 aa)
FYNTyrosine-protein kinase. (537 aa)
TEKTEK receptor tyrosine kinase. (1125 aa)
DAPK1Death associated protein kinase 1. (1430 aa)
SYKSpleen associated tyrosine kinase. (637 aa)
ATG101Autophagy related 101. (218 aa)
SLKSTE20 like kinase. (1241 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1341 aa)
LCKTyrosine-protein kinase. (417 aa)
AAK1AP2 associated kinase 1. (963 aa)
ENSPCOP00000010360AGC-kinase C-terminal domain-containing protein. (86 aa)
TNK1Tyrosine kinase non receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (662 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
PIM2Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (311 aa)
NEK2NIMA related kinase 2. (413 aa)
HCKTyrosine-protein kinase. (524 aa)
ENSPCOP00000013124Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (435 aa)
CLK1CDC like kinase 1. (523 aa)
EIF2S1S1 motif domain-containing protein. (257 aa)
TSSK4Testis specific serine kinase 4. (338 aa)
ROS1Tyrosine-protein kinase receptor. (2630 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
STK4Serine/threonine kinase 4. (487 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
AURKBProtein kinase domain-containing protein. (162 aa)
EPHB1EPH receptor B1. (984 aa)
STK10Serine/threonine kinase 10. (968 aa)
DYRK1ADual specificity tyrosine phosphorylation regulated kinase 1A. (714 aa)
TRIM24Tripartite motif containing 24. (984 aa)
ENSPCOP00000015643S1 motif domain-containing protein. (294 aa)
CDK12Cyclin dependent kinase 12. (1490 aa)
ENSPCOP00000000463Uncharacterized protein. (72 aa)
ULK1Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1045 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
MAKMale germ cell associated kinase. (589 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2536 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (860 aa)
CAMKK2Calcium/calmodulin dependent protein kinase kinase 2. (587 aa)
OXSR1Oxidative stress responsive kinase 1. (527 aa)
FGFR1Fibroblast growth factor receptor. (846 aa)
SIK2Salt inducible kinase 2. (890 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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