(31 nodes) Embryonic eye morphogenesis network (Propithecus coquereli)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SIX3	SIX homeobox 3. (333 aa)
	TH	Tyrosine hydroxylase. (497 aa)
	STRA6	Stimulated by retinoic acid 6. (687 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
	PHACTR4	Phosphatase and actin regulator. (702 aa)
	WNT16	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
	ALDH1A3	Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
	SP3	Sp3 transcription factor. (781 aa)
	FBN2	Fibrillin 2. (2912 aa)
	SOX11	Transcription factor SOX. (442 aa)
	VAX2	Ventral anterior homeobox 2. (290 aa)
	PAX6	Paired box 6. (453 aa)
	HIPK1	Homeodomain interacting protein kinase 1. (1131 aa)
	FBN1	Fibrillin 1. (2871 aa)
	PROX1	Prospero homeobox 1. (737 aa)
	RARG	Retinoic acid receptor gamma. (458 aa)
	PAX2	Paired box 2. (417 aa)
	TFAP2A	Transcription factor AP-2 alpha. (439 aa)
	FRS2	Fibroblast growth factor receptor substrate 2. (508 aa)
	ZEB1	Zinc finger E-box binding homeobox 1. (1002 aa)
	MFAP2	Microfibril associated protein 2. (181 aa)
	FOXF2	Forkhead box F2. (405 aa)
	IFT172	Intraflagellar transport 172. (1723 aa)
	CITED2	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa)
	RARB	Retinoic acid receptor beta. (448 aa)
	MFAP5	Microfibril associated protein 5. (158 aa)
	IHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
	BMP7	Bone morphogenetic protein 7. (431 aa)
	TBX2	T-box transcription factor 2. (713 aa)
	HIPK2	Homeodomain interacting protein kinase 2. (1187 aa)
	KDM2B	Lysine demethylase 2B. (1337 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALDH1A3	STRA6	ENSPCOP00000011166	ENSPCOP00000007744	Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family.	Stimulated by retinoic acid 6.	0.460
BMP7	FBN1	ENSPCOP00000003744	ENSPCOP00000027346	Bone morphogenetic protein 7.	Fibrillin 1.	0.532
CITED2	TFAP2A	ENSPCOP00000021854	ENSPCOP00000018477	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2.	Transcription factor AP-2 alpha.	0.869
FBN1	BMP7	ENSPCOP00000027346	ENSPCOP00000003744	Fibrillin 1.	Bone morphogenetic protein 7.	0.532
FBN1	FBN2	ENSPCOP00000027346	ENSPCOP00000011887	Fibrillin 1.	Fibrillin 2.	0.826
FBN1	MFAP2	ENSPCOP00000027346	ENSPCOP00000020269	Fibrillin 1.	Microfibril associated protein 2.	0.897
FBN1	MFAP5	ENSPCOP00000027346	ENSPCOP00000022832	Fibrillin 1.	Microfibril associated protein 5.	0.868
FBN2	FBN1	ENSPCOP00000011887	ENSPCOP00000027346	Fibrillin 2.	Fibrillin 1.	0.826
FBN2	MFAP2	ENSPCOP00000011887	ENSPCOP00000020269	Fibrillin 2.	Microfibril associated protein 2.	0.860
FBN2	MFAP5	ENSPCOP00000011887	ENSPCOP00000022832	Fibrillin 2.	Microfibril associated protein 5.	0.830
FOXF2	IHH	ENSPCOP00000020341	ENSPCOP00000002411	Forkhead box F2.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.480
HIPK1	HIPK2	ENSPCOP00000028119	ENSPCOP00000003838	Homeodomain interacting protein kinase 1.	Homeodomain interacting protein kinase 2.	0.845
HIPK2	HIPK1	ENSPCOP00000003838	ENSPCOP00000028119	Homeodomain interacting protein kinase 2.	Homeodomain interacting protein kinase 1.	0.845
IFT172	STRA6	ENSPCOP00000021627	ENSPCOP00000007744	Intraflagellar transport 172.	Stimulated by retinoic acid 6.	0.551
IHH	FOXF2	ENSPCOP00000002411	ENSPCOP00000020341	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Forkhead box F2.	0.480
MFAP2	FBN1	ENSPCOP00000020269	ENSPCOP00000027346	Microfibril associated protein 2.	Fibrillin 1.	0.897
MFAP2	FBN2	ENSPCOP00000020269	ENSPCOP00000011887	Microfibril associated protein 2.	Fibrillin 2.	0.860
MFAP2	MFAP5	ENSPCOP00000020269	ENSPCOP00000022832	Microfibril associated protein 2.	Microfibril associated protein 5.	0.825
MFAP5	FBN1	ENSPCOP00000022832	ENSPCOP00000027346	Microfibril associated protein 5.	Fibrillin 1.	0.868
MFAP5	FBN2	ENSPCOP00000022832	ENSPCOP00000011887	Microfibril associated protein 5.	Fibrillin 2.	0.830