(11 nodes) Behavioral response to cocaine network (Propithecus coquereli)

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	EHMT2	Euchromatic histone lysine methyltransferase 2. (1267 aa)
	HOMER1	Homer scaffold protein 1. (329 aa)
	PPP1R1B	Protein phosphatase 1 regulatory inhibitor subunit 1B. (204 aa)
	DRD4	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (333 aa)
	CDK5	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	HOMER2	Homer scaffold protein 2. (366 aa)
	FADD	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (205 aa)
	ABAT	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa)
	DRD3	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (400 aa)
	SDK1	Sidekick cell adhesion molecule 1. (2011 aa)
	DRD2	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDK5	FADD	ENSPCOP00000026355	ENSPCOP00000021807	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.427
CDK5	PPP1R1B	ENSPCOP00000026355	ENSPCOP00000028111	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	Protein phosphatase 1 regulatory inhibitor subunit 1B.	0.913
DRD2	DRD3	ENSPCOP00000002488	ENSPCOP00000009227	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.875
DRD2	DRD4	ENSPCOP00000002488	ENSPCOP00000027225	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	0.884
DRD2	PPP1R1B	ENSPCOP00000002488	ENSPCOP00000028111	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	Protein phosphatase 1 regulatory inhibitor subunit 1B.	0.457
DRD3	DRD2	ENSPCOP00000009227	ENSPCOP00000002488	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	0.875
DRD3	DRD4	ENSPCOP00000009227	ENSPCOP00000027225	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	0.895
DRD4	DRD2	ENSPCOP00000027225	ENSPCOP00000002488	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	0.884
DRD4	DRD3	ENSPCOP00000027225	ENSPCOP00000009227	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.895
FADD	CDK5	ENSPCOP00000021807	ENSPCOP00000026355	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	0.427
HOMER1	HOMER2	ENSPCOP00000028647	ENSPCOP00000026281	Homer scaffold protein 1.	Homer scaffold protein 2.	0.982
HOMER2	HOMER1	ENSPCOP00000026281	ENSPCOP00000028647	Homer scaffold protein 2.	Homer scaffold protein 1.	0.982
PPP1R1B	CDK5	ENSPCOP00000028111	ENSPCOP00000026355	Protein phosphatase 1 regulatory inhibitor subunit 1B.	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	0.913
PPP1R1B	DRD2	ENSPCOP00000028111	ENSPCOP00000002488	Protein phosphatase 1 regulatory inhibitor subunit 1B.	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	0.457