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ENSPCOP00000004787 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (445 aa) | ||||
NOTCH1 | Notch receptor 1. (2420 aa) | ||||
BOK | BCL2 family apoptosis regulator BOK. (213 aa) | ||||
OLIG1 | Oligodendrocyte transcription factor 1. (267 aa) | ||||
FA2H | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa) | ||||
B4GALT5 | Beta-1,4-galactosyltransferase 5. (355 aa) | ||||
EIF2B5 | Eukaryotic translation initiation factor 2B subunit epsilon. (722 aa) | ||||
SOX11 | Transcription factor SOX. (442 aa) | ||||
NKX2-1 | NK2 homeobox 1. (401 aa) | ||||
SOX9 | SRY-box transcription factor 9. (505 aa) | ||||
PAX6 | Paired box 6. (453 aa) | ||||
NSUN5 | NOP2/Sun RNA methyltransferase 5; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (466 aa) | ||||
ERBB2 | Receptor protein-tyrosine kinase. (1252 aa) | ||||
NKX6-1 | NK6 homeobox 1. (367 aa) | ||||
OLIG2 | Oligodendrocyte transcription factor 2. (320 aa) | ||||
PTPRZ1 | Protein tyrosine phosphatase receptor type Z1. (2086 aa) | ||||
ASPA | Aspartoacylase. (313 aa) | ||||
CDK5 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa) | ||||
NF1 | Neurofibromin 1. (2841 aa) | ||||
CSK | Tyrosine-protein kinase. (450 aa) | ||||
DUSP10 | Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa) | ||||
HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa) | ||||
LYN | Tyrosine-protein kinase. (512 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) | ||||
CTNNB1 | Catenin beta 1. (781 aa) | ||||
MED12 | Mediator complex subunit 12. (2187 aa) | ||||
CNTN2 | Contactin 2. (1040 aa) | ||||
ENSPCOP00000021800 | Uncharacterized protein. (175 aa) | ||||
SOX8 | SRY-box transcription factor 8. (462 aa) | ||||
SOX10 | SRY-box transcription factor 10. (468 aa) | ||||
CNP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family. (421 aa) | ||||
PRDM8 | PR/SET domain 8. (569 aa) | ||||
MAL | Mal, T cell differentiation protein. (153 aa) | ||||
TSPAN2 | Tetraspanin. (221 aa) | ||||
EIF2B1 | Eukaryotic translation initiation factor 2B subunit alpha; Belongs to the eIF-2B alpha/beta/delta subunits family. (305 aa) | ||||
ABCA2 | ATP binding cassette subfamily A member 2. (2452 aa) | ||||
PLP1 | Proteolipid protein 1. (277 aa) | ||||
ENSPCOP00000018033 | HH_signal domain-containing protein. (110 aa) | ||||
NKX6-2 | NK6 homeobox 2. (277 aa) | ||||
EIF2B4 | Eukaryotic translation initiation factor 2B subunit delta; Belongs to the eIF-2B alpha/beta/delta subunits family. (524 aa) | ||||
DLX1 | Distal-less homeobox 1. (255 aa) | ||||
GLI3 | GLI family zinc finger 3. (1580 aa) | ||||
EIF2B3 | Eukaryotic translation initiation factor 2B subunit gamma. (414 aa) | ||||
NTRK2 | Tyrosine-protein kinase receptor. (838 aa) | ||||
NCSTN | Nicastrin. (708 aa) | ||||
PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) | ||||
MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2536 aa) | ||||
CNTNAP1 | Contactin associated protein 1. (1382 aa) | ||||
SOX6 | SRY-box transcription factor 6. (828 aa) | ||||
B4GALT6 | Beta-1,4-galactosyltransferase 6. (336 aa) | ||||
CLU | Clusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (450 aa) | ||||
DLX2 | Distal-less homeobox 2. (328 aa) | ||||
SOX13 | SRY-box transcription factor 13. (615 aa) | ||||
MYRF | Myelin regulatory factor. (1143 aa) | ||||
WASF3 | WASP family member 3. (485 aa) | ||||
MAG | Myelin associated glycoprotein. (626 aa) | ||||
CNTN1 | Contactin 1. (1018 aa) | ||||
BNIP3 | Uncharacterized protein. (235 aa) | ||||
CDKN2C | Cyclin dependent kinase inhibitor 2C. (168 aa) | ||||
SLC8A3 | Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa) | ||||
ID4 | Inhibitor of DNA binding 4, HLH protein. (161 aa) | ||||
TRPC4 | Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (982 aa) | ||||
ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit. (681 aa) | ||||
LPAR1 | Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (365 aa) | ||||
TPPP | Tubulin polymerization promoting protein. (210 aa) | ||||
ACY3 | Aminoacylase 3. (319 aa) | ||||
EIF2B2 | Eukaryotic translation initiation factor 2B subunit beta; Belongs to the eIF-2B alpha/beta/delta subunits family. (351 aa) | ||||
NKX2-2 | NK2 homeobox 2. (273 aa) | ||||
RHEB | Ras homolog, mTORC1 binding. (184 aa) | ||||
NRG1 | Neuregulin 1. (710 aa) | ||||
HES5 | Orange domain-containing protein. (94 aa) | ||||
SUZ12 | SUZ12 polycomb repressive complex 2 subunit. (739 aa) | ||||
TENM4 | Teneurin transmembrane protein 4. (2769 aa) |