STRINGSTRING
ENSPCOP00000004787 ENSPCOP00000004787 NOTCH1 NOTCH1 BOK BOK OLIG1 OLIG1 FA2H FA2H B4GALT5 B4GALT5 EIF2B5 EIF2B5 SOX11 SOX11 NKX2-1 NKX2-1 SOX9 SOX9 PAX6 PAX6 NSUN5 NSUN5 ERBB2 ERBB2 NKX6-1 NKX6-1 OLIG2 OLIG2 PTPRZ1 PTPRZ1 ASPA ASPA CDK5 CDK5 NF1 NF1 CSK CSK DUSP10 DUSP10 HDAC1 HDAC1 LYN LYN TGFB1 TGFB1 CTNNB1 CTNNB1 MED12 MED12 CNTN2 CNTN2 ENSPCOP00000021800 ENSPCOP00000021800 SOX8 SOX8 SOX10 SOX10 CNP CNP PRDM8 PRDM8 MAL MAL TSPAN2 TSPAN2 EIF2B1 EIF2B1 ABCA2 ABCA2 PLP1 PLP1 ENSPCOP00000018033 ENSPCOP00000018033 NKX6-2 NKX6-2 EIF2B4 EIF2B4 DLX1 DLX1 GLI3 GLI3 EIF2B3 EIF2B3 NTRK2 NTRK2 NCSTN NCSTN PTEN PTEN MTOR MTOR CNTNAP1 CNTNAP1 SOX6 SOX6 B4GALT6 B4GALT6 CLU CLU DLX2 DLX2 SOX13 SOX13 MYRF MYRF WASF3 WASF3 MAG MAG CNTN1 CNTN1 BNIP3 BNIP3 CDKN2C CDKN2C SLC8A3 SLC8A3 ID4 ID4 TRPC4 TRPC4 ERCC2 ERCC2 LPAR1 LPAR1 TPPP TPPP ACY3 ACY3 EIF2B2 EIF2B2 NKX2-2 NKX2-2 RHEB RHEB NRG1 NRG1 HES5 HES5 SUZ12 SUZ12 TENM4 TENM4
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ENSPCOP00000004787Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (445 aa)
NOTCH1Notch receptor 1. (2420 aa)
BOKBCL2 family apoptosis regulator BOK. (213 aa)
OLIG1Oligodendrocyte transcription factor 1. (267 aa)
FA2HFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa)
B4GALT5Beta-1,4-galactosyltransferase 5. (355 aa)
EIF2B5Eukaryotic translation initiation factor 2B subunit epsilon. (722 aa)
SOX11Transcription factor SOX. (442 aa)
NKX2-1NK2 homeobox 1. (401 aa)
SOX9SRY-box transcription factor 9. (505 aa)
PAX6Paired box 6. (453 aa)
NSUN5NOP2/Sun RNA methyltransferase 5; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (466 aa)
ERBB2Receptor protein-tyrosine kinase. (1252 aa)
NKX6-1NK6 homeobox 1. (367 aa)
OLIG2Oligodendrocyte transcription factor 2. (320 aa)
PTPRZ1Protein tyrosine phosphatase receptor type Z1. (2086 aa)
ASPAAspartoacylase. (313 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
NF1Neurofibromin 1. (2841 aa)
CSKTyrosine-protein kinase. (450 aa)
DUSP10Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
LYNTyrosine-protein kinase. (512 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
CTNNB1Catenin beta 1. (781 aa)
MED12Mediator complex subunit 12. (2187 aa)
CNTN2Contactin 2. (1040 aa)
ENSPCOP00000021800Uncharacterized protein. (175 aa)
SOX8SRY-box transcription factor 8. (462 aa)
SOX10SRY-box transcription factor 10. (468 aa)
CNP2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family. (421 aa)
PRDM8PR/SET domain 8. (569 aa)
MALMal, T cell differentiation protein. (153 aa)
TSPAN2Tetraspanin. (221 aa)
EIF2B1Eukaryotic translation initiation factor 2B subunit alpha; Belongs to the eIF-2B alpha/beta/delta subunits family. (305 aa)
ABCA2ATP binding cassette subfamily A member 2. (2452 aa)
PLP1Proteolipid protein 1. (277 aa)
ENSPCOP00000018033HH_signal domain-containing protein. (110 aa)
NKX6-2NK6 homeobox 2. (277 aa)
EIF2B4Eukaryotic translation initiation factor 2B subunit delta; Belongs to the eIF-2B alpha/beta/delta subunits family. (524 aa)
DLX1Distal-less homeobox 1. (255 aa)
GLI3GLI family zinc finger 3. (1580 aa)
EIF2B3Eukaryotic translation initiation factor 2B subunit gamma. (414 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
NCSTNNicastrin. (708 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2536 aa)
CNTNAP1Contactin associated protein 1. (1382 aa)
SOX6SRY-box transcription factor 6. (828 aa)
B4GALT6Beta-1,4-galactosyltransferase 6. (336 aa)
CLUClusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (450 aa)
DLX2Distal-less homeobox 2. (328 aa)
SOX13SRY-box transcription factor 13. (615 aa)
MYRFMyelin regulatory factor. (1143 aa)
WASF3WASP family member 3. (485 aa)
MAGMyelin associated glycoprotein. (626 aa)
CNTN1Contactin 1. (1018 aa)
BNIP3Uncharacterized protein. (235 aa)
CDKN2CCyclin dependent kinase inhibitor 2C. (168 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa)
ID4Inhibitor of DNA binding 4, HLH protein. (161 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (982 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (681 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (365 aa)
TPPPTubulin polymerization promoting protein. (210 aa)
ACY3Aminoacylase 3. (319 aa)
EIF2B2Eukaryotic translation initiation factor 2B subunit beta; Belongs to the eIF-2B alpha/beta/delta subunits family. (351 aa)
NKX2-2NK2 homeobox 2. (273 aa)
RHEBRas homolog, mTORC1 binding. (184 aa)
NRG1Neuregulin 1. (710 aa)
HES5Orange domain-containing protein. (94 aa)
SUZ12SUZ12 polycomb repressive complex 2 subunit. (739 aa)
TENM4Teneurin transmembrane protein 4. (2769 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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